Specific elimination of m.8993T>G mitochondrial haplotype in NARP cybrid cells by CRISPR-Cas9 system › Research Explorer

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Specific elimination of m.8993T>G mitochondrial haplotype in NARP cybrid cells by CRISPR-Cas9 system

Research output: Contribution to journal › Article › peer-review

DOI

https://doi.org/10.1038/s41598-026-49007-y
Final published version

Elvira Zakirova
Svetlana Sergeeva
Ksenia Morozova
Elena Kiseleva
Masashi Tanaka
Ilya Mazunin
Konstantin Orishchenko

Original language	English
Article number	19745
Number of pages	18
Journal	Scientific Reports
Volume	16
Issue number	1
DOIs	https://doi.org/10.1038/s41598-026-49007-y
Publication status	Published - 28 Apr 2026

OECD FOS+WOS

1.06.KM GENETICS & HEREDITY

Research areas

CRISPR-SpCas9, Heteroplasmy shift, Mitochondria, NARP syndrome, m.8993T>G point mutation

ID: 79923369