Soloxolone N-3-(Dimethylamino)propylamide Suppresses Tumor Growth and Mitigates Doxorubicin-Induced Hepatotoxicity in RLS40 Lymphosarcoma-Bearing Mice

Original language	English
Article number	11912
Number of pages	24
Journal	International Journal of Molecular Sciences
Volume	26
Issue number	24
DOIs	https://doi.org/10.3390/ijms262411912
Publication status	Published - 10 Dec 2025

Animals, Doxorubicin/adverse effects, Mice, Humans, Chemical and Drug Induced Liver Injury/drug therapy, NF-E2-Related Factor 2/metabolism, Apoptosis/drug effects, Hep G2 Cells, Heme Oxygenase-1/metabolism, Cell Line, Tumor, ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism, Antineoplastic Agents/pharmacology, Drug Resistance, Neoplasm/drug effects, Male, Liver/drug effects, Xenograft Model Antitumor Assays, Cell Proliferation/drug effects

ID: 73962925