Saposin-like proteins in Opisthorchis felineus and related opisthorchids

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Saposin-like proteins in Opisthorchis felineus and related opisthorchids. / Pirozhkova, Daria; Katokhin, Alexey.

In: Infection, Genetics and Evolution, Vol. 78, 104132, 03.2020.

Research output: Contribution to journal › Article › peer-review

Harvard

Pirozhkova, D & Katokhin, A 2020, 'Saposin-like proteins in Opisthorchis felineus and related opisthorchids', Infection, Genetics and Evolution, vol. 78, 104132. https://doi.org/10.1016/j.meegid.2019.104132

APA

Pirozhkova, D., & Katokhin, A. (2020). Saposin-like proteins in Opisthorchis felineus and related opisthorchids. Infection, Genetics and Evolution, 78, [104132]. https://doi.org/10.1016/j.meegid.2019.104132

Vancouver

Pirozhkova D, Katokhin A. Saposin-like proteins in Opisthorchis felineus and related opisthorchids. Infection, Genetics and Evolution. 2020 Mar;78:104132. Epub 2019 Dec 2. doi: 10.1016/j.meegid.2019.104132

Author

Pirozhkova, Daria ; Katokhin, Alexey. / Saposin-like proteins in Opisthorchis felineus and related opisthorchids. In: Infection, Genetics and Evolution. 2020 ; Vol. 78.

BibTeX

@article{0694cb27bed8451baa42e5e12962c12e,

title = "Saposin-like proteins in Opisthorchis felineus and related opisthorchids",

abstract = "Saposin B domain-containing or saposin-like proteins (SAPs, SAPLIPs) have been described as lipid/membrane-binding and often show antibacterial and cytolytic activity. Members of this protein family are present in phylogenetically distant organisms, pointing to their functional importance. Several SAPs are found in trematodes and some of them apparently are related to host-parasite interaction as they show cytolytic activity or immunogenicity. In the present study, we search for SAP genes of Opisthorchis felineus, Clonorchis sinensis and O. viverrini, compare and analyze their structure and expression patterns. We define three orthologous groups of SAPs in opisthorchids and suggest a unique protein motif with unknown function in one group of orthologs.",

keywords = "Gene expression, opisthorchids, Opisthorchis felineus, Orthology, saposin B domain, TRANSCRIPTOME, NK-LYSIN, EXPRESSION, MEMBER, FAMILY",

author = "Daria Pirozhkova and Alexey Katokhin",

year = "2020",

month = mar,

doi = "10.1016/j.meegid.2019.104132",

language = "English",

volume = "78",

journal = "Infection, Genetics and Evolution",

issn = "1567-1348",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Saposin-like proteins in Opisthorchis felineus and related opisthorchids

AU - Pirozhkova, Daria

AU - Katokhin, Alexey

PY - 2020/3

Y1 - 2020/3

N2 - Saposin B domain-containing or saposin-like proteins (SAPs, SAPLIPs) have been described as lipid/membrane-binding and often show antibacterial and cytolytic activity. Members of this protein family are present in phylogenetically distant organisms, pointing to their functional importance. Several SAPs are found in trematodes and some of them apparently are related to host-parasite interaction as they show cytolytic activity or immunogenicity. In the present study, we search for SAP genes of Opisthorchis felineus, Clonorchis sinensis and O. viverrini, compare and analyze their structure and expression patterns. We define three orthologous groups of SAPs in opisthorchids and suggest a unique protein motif with unknown function in one group of orthologs.

AB - Saposin B domain-containing or saposin-like proteins (SAPs, SAPLIPs) have been described as lipid/membrane-binding and often show antibacterial and cytolytic activity. Members of this protein family are present in phylogenetically distant organisms, pointing to their functional importance. Several SAPs are found in trematodes and some of them apparently are related to host-parasite interaction as they show cytolytic activity or immunogenicity. In the present study, we search for SAP genes of Opisthorchis felineus, Clonorchis sinensis and O. viverrini, compare and analyze their structure and expression patterns. We define three orthologous groups of SAPs in opisthorchids and suggest a unique protein motif with unknown function in one group of orthologs.

KW - Gene expression

KW - opisthorchids

KW - Opisthorchis felineus

KW - Orthology

KW - saposin B domain

KW - TRANSCRIPTOME

KW - NK-LYSIN

KW - EXPRESSION

KW - MEMBER

KW - FAMILY

UR - http://www.scopus.com/inward/record.url?scp=85075871095&partnerID=8YFLogxK

U2 - 10.1016/j.meegid.2019.104132

DO - 10.1016/j.meegid.2019.104132

M3 - Article

C2 - 31805380

AN - SCOPUS:85075871095

VL - 78

JO - Infection, Genetics and Evolution

JF - Infection, Genetics and Evolution

SN - 1567-1348

M1 - 104132

ER -

ID: 22600350