Role of the low-selective organic anion transport in regulation of osmotic balance of renal collecting duct principal cells under hypo-osmotic conditions

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Role of the low-selective organic anion transport in regulation of osmotic balance of renal collecting duct principal cells under hypo-osmotic conditions. / Baturina, G. S.; Katkova, L. E.; Solenov, E. I. et al.

In: Doklady Biological Sciences, Vol. 473, No. 1, 01.03.2017, p. 43-45.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{7f504b0398484eee920a916a2c890bb8,

title = "Role of the low-selective organic anion transport in regulation of osmotic balance of renal collecting duct principal cells under hypo-osmotic conditions",

abstract = "In the course of adaptation of the rat kidney collecting duct cells to hypo-osmotic medium, the organic anion transporter inhibitor probenecid reduced significantly the regulatory cell volume decrease in response to a hypotonic shock. Both probenecid and hypotonic shock delayed significantly the entry into a cell of the fluorescent dye calcein, which exists as anion at neutral pH. Thus, the organic osmolyte transport plays an important role in the regulatory decrease of the principal cell volume under the hypo-osmotic conditions.",

author = "Baturina, {G. S.} and Katkova, {L. E.} and Solenov, {E. I.} and Ivanova, {L. N.}",

note = "Publisher Copyright: {\textcopyright} 2017, Pleiades Publishing, Ltd.",

year = "2017",

month = mar,

day = "1",

doi = "10.1134/S0012496617020090",

language = "English",

volume = "473",

pages = "43--45",

journal = "Doklady Biological Sciences",

issn = "0012-4966",

publisher = "Maik Nauka-Interperiodica Publishing",

number = "1",

}

RIS

TY - JOUR

T1 - Role of the low-selective organic anion transport in regulation of osmotic balance of renal collecting duct principal cells under hypo-osmotic conditions

AU - Baturina, G. S.

AU - Katkova, L. E.

AU - Solenov, E. I.

AU - Ivanova, L. N.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - In the course of adaptation of the rat kidney collecting duct cells to hypo-osmotic medium, the organic anion transporter inhibitor probenecid reduced significantly the regulatory cell volume decrease in response to a hypotonic shock. Both probenecid and hypotonic shock delayed significantly the entry into a cell of the fluorescent dye calcein, which exists as anion at neutral pH. Thus, the organic osmolyte transport plays an important role in the regulatory decrease of the principal cell volume under the hypo-osmotic conditions.

AB - In the course of adaptation of the rat kidney collecting duct cells to hypo-osmotic medium, the organic anion transporter inhibitor probenecid reduced significantly the regulatory cell volume decrease in response to a hypotonic shock. Both probenecid and hypotonic shock delayed significantly the entry into a cell of the fluorescent dye calcein, which exists as anion at neutral pH. Thus, the organic osmolyte transport plays an important role in the regulatory decrease of the principal cell volume under the hypo-osmotic conditions.

UR - http://www.scopus.com/inward/record.url?scp=85028678540&partnerID=8YFLogxK

U2 - 10.1134/S0012496617020090

DO - 10.1134/S0012496617020090

M3 - Article

C2 - 28508198

AN - SCOPUS:85028678540

VL - 473

SP - 43

EP - 45

JO - Doklady Biological Sciences

JF - Doklady Biological Sciences

SN - 0012-4966

IS - 1

ER -

ID: 9917045