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Resting-state fMRI study of patients with fragile X syndrome. / Isanova, E.; Petrovskiy, E.; Savelov, A. et al.

In: Journal of Physics: Conference Series, Vol. 886, No. 1, 012007, 29.08.2017.

Research output: Contribution to journal › Article › peer-review

Harvard

Isanova, E, Petrovskiy, E, Savelov, A, Yudkin, D & Tulupov, A 2017, 'Resting-state fMRI study of patients with fragile X syndrome', Journal of Physics: Conference Series, vol. 886, no. 1, 012007. https://doi.org/10.1088/1742-6596/886/1/012007

APA

Isanova, E., Petrovskiy, E., Savelov, A., Yudkin, D., & Tulupov, A. (2017). Resting-state fMRI study of patients with fragile X syndrome. Journal of Physics: Conference Series, 886(1), [012007]. https://doi.org/10.1088/1742-6596/886/1/012007

Vancouver

Isanova E, Petrovskiy E, Savelov A, Yudkin D, Tulupov A. Resting-state fMRI study of patients with fragile X syndrome. Journal of Physics: Conference Series. 2017 Aug 29;886(1):012007. doi: 10.1088/1742-6596/886/1/012007

Author

Isanova, E. ; Petrovskiy, E. ; Savelov, A. et al. / Resting-state fMRI study of patients with fragile X syndrome. In: Journal of Physics: Conference Series. 2017 ; Vol. 886, No. 1.

BibTeX

@article{46c49b4e2a0e4528a5b1fd1ea7fb9d3a,
title = "Resting-state fMRI study of patients with fragile X syndrome",
abstract = "The study aimed to assess the neural activity of different brain regions in patients with fragile X syndrome (FXS) and the healthy volunteers by resting-state functional magnetic resonance imaging (fMRI) on a 1.5 T MRI Achieva scanner (Philips). Results: The fMRI study showed a DMN of brain function in patients with FXS, as well as in the healthy volunteers. Furthermore, it was found that a default mode network of the brain in patients with FXS and healthy volunteers does not have statistically significant differences (p>0.05), which may indicate that the basal activity of neurons in patients with FXS is not reduced. In addition, we have found a significant (p<0.001) increase in the FC within the right inferior parietal and right angular gyrus in the resting state in patients with FXS. Conclusion: New data of functional status of the brain in patients with FXS were received. The significant increase in the resting state functional connectivity within the right inferior parietal and right angular gyrus (p<0.001) in patients with FXS was found.",
keywords = "BRAIN",
author = "E. Isanova and E. Petrovskiy and A. Savelov and D. Yudkin and A. Tulupov",
note = "Publisher Copyright: {\textcopyright} Published under licence by IOP Publishing Ltd.",
year = "2017",
month = aug,
day = "29",
doi = "10.1088/1742-6596/886/1/012007",
language = "English",
volume = "886",
journal = "Journal of Physics: Conference Series",
issn = "1742-6588",
publisher = "IOP Publishing Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Resting-state fMRI study of patients with fragile X syndrome

AU - Isanova, E.

AU - Petrovskiy, E.

AU - Savelov, A.

AU - Yudkin, D.

AU - Tulupov, A.

N1 - Publisher Copyright: © Published under licence by IOP Publishing Ltd.

PY - 2017/8/29

Y1 - 2017/8/29

N2 - The study aimed to assess the neural activity of different brain regions in patients with fragile X syndrome (FXS) and the healthy volunteers by resting-state functional magnetic resonance imaging (fMRI) on a 1.5 T MRI Achieva scanner (Philips). Results: The fMRI study showed a DMN of brain function in patients with FXS, as well as in the healthy volunteers. Furthermore, it was found that a default mode network of the brain in patients with FXS and healthy volunteers does not have statistically significant differences (p>0.05), which may indicate that the basal activity of neurons in patients with FXS is not reduced. In addition, we have found a significant (p<0.001) increase in the FC within the right inferior parietal and right angular gyrus in the resting state in patients with FXS. Conclusion: New data of functional status of the brain in patients with FXS were received. The significant increase in the resting state functional connectivity within the right inferior parietal and right angular gyrus (p<0.001) in patients with FXS was found.

AB - The study aimed to assess the neural activity of different brain regions in patients with fragile X syndrome (FXS) and the healthy volunteers by resting-state functional magnetic resonance imaging (fMRI) on a 1.5 T MRI Achieva scanner (Philips). Results: The fMRI study showed a DMN of brain function in patients with FXS, as well as in the healthy volunteers. Furthermore, it was found that a default mode network of the brain in patients with FXS and healthy volunteers does not have statistically significant differences (p>0.05), which may indicate that the basal activity of neurons in patients with FXS is not reduced. In addition, we have found a significant (p<0.001) increase in the FC within the right inferior parietal and right angular gyrus in the resting state in patients with FXS. Conclusion: New data of functional status of the brain in patients with FXS were received. The significant increase in the resting state functional connectivity within the right inferior parietal and right angular gyrus (p<0.001) in patients with FXS was found.

KW - BRAIN

UR - http://www.scopus.com/inward/record.url?scp=85029582001&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/886/1/012007

DO - 10.1088/1742-6596/886/1/012007

M3 - Article

AN - SCOPUS:85029582001

VL - 886

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

SN - 1742-6588

IS - 1

M1 - 012007

ER -

ID: 8690611