Standard

Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor. / Nuzhdin, Alexey L.; Simonov, Pavel A.; Bukhtiyarova, Galina A. et al.

In: Molecular Catalysis, Vol. 499, 111297, 01.2021.

Research output: Contribution to journal › Article › peer-review

Harvard

Nuzhdin, AL, Simonov, PA, Bukhtiyarova, GA, Eltsov, IV & Bukhtiyarov, VI 2021, 'Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor', Molecular Catalysis, vol. 499, 111297. https://doi.org/10.1016/j.mcat.2020.111297

APA

Nuzhdin, A. L., Simonov, P. A., Bukhtiyarova, G. A., Eltsov, I. V., & Bukhtiyarov, V. I. (2021). Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor. Molecular Catalysis, 499, [111297]. https://doi.org/10.1016/j.mcat.2020.111297

Vancouver

Nuzhdin AL, Simonov PA, Bukhtiyarova GA, Eltsov IV, Bukhtiyarov VI. Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor. Molecular Catalysis. 2021 Jan;499:111297. Epub 2020 Nov 19. doi: 10.1016/j.mcat.2020.111297

Author

Nuzhdin, Alexey L. ; Simonov, Pavel A. ; Bukhtiyarova, Galina A. et al. / Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor. In: Molecular Catalysis. 2021 ; Vol. 499.

BibTeX

@article{af4ad08a99af4e1aadeb2381157f0f43,
title = "Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor",
abstract = "Aminomethylhydroxymethylfuran derivatives are well known for their pharmaceutical activities. In this work, the two-step one-pot procedure for the synthesis of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was proposed, which includes two successive reactions: the condensation of 5-acetoxymethylfurfural (AMF) with primary amines and the reduction of obtained imines with hydrogen over supported metal catalysts in a flow reactor. The comparison of the properties of Au, Pd and Pt catalysts in the hydrogenation of imine obtained by reaction of AMF with aniline showed that Pt-based catalysts (both Pt/Al2O3 and Pt/C) are highly active and provide high selectivity and stability, while Pd and Au nanoparticles supported on γ-alumina and carbon show low selectivity. A wide range of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was synthesized in good to excellent yields using Pt/Al2O3 catalyst and methanol as a solvent.",
keywords = "5-Acetoxymethylfurfural, Flow hydrogenation, Primary amines, Pt/AlOcatalyst, Reductive amination, Pt/Al(2)O(3)catalyst, HYDROGENATION, AMINES, BIOMASS, ALDEHYDES, UTILITY",
author = "Nuzhdin, {Alexey L.} and Simonov, {Pavel A.} and Bukhtiyarova, {Galina A.} and Eltsov, {Ilia V.} and Bukhtiyarov, {Valerii I.}",
note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2021",
month = jan,
doi = "10.1016/j.mcat.2020.111297",
language = "English",
volume = "499",
journal = "Molecular Catalysis",
issn = "2468-8231",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Reductive amination of 5-acetoxymethylfurfural over Pt/Al2O3 catalyst in a flow reactor

AU - Nuzhdin, Alexey L.

AU - Simonov, Pavel A.

AU - Bukhtiyarova, Galina A.

AU - Eltsov, Ilia V.

AU - Bukhtiyarov, Valerii I.

N1 - Publisher Copyright: © 2020 Elsevier B.V. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2021/1

Y1 - 2021/1

N2 - Aminomethylhydroxymethylfuran derivatives are well known for their pharmaceutical activities. In this work, the two-step one-pot procedure for the synthesis of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was proposed, which includes two successive reactions: the condensation of 5-acetoxymethylfurfural (AMF) with primary amines and the reduction of obtained imines with hydrogen over supported metal catalysts in a flow reactor. The comparison of the properties of Au, Pd and Pt catalysts in the hydrogenation of imine obtained by reaction of AMF with aniline showed that Pt-based catalysts (both Pt/Al2O3 and Pt/C) are highly active and provide high selectivity and stability, while Pd and Au nanoparticles supported on γ-alumina and carbon show low selectivity. A wide range of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was synthesized in good to excellent yields using Pt/Al2O3 catalyst and methanol as a solvent.

AB - Aminomethylhydroxymethylfuran derivatives are well known for their pharmaceutical activities. In this work, the two-step one-pot procedure for the synthesis of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was proposed, which includes two successive reactions: the condensation of 5-acetoxymethylfurfural (AMF) with primary amines and the reduction of obtained imines with hydrogen over supported metal catalysts in a flow reactor. The comparison of the properties of Au, Pd and Pt catalysts in the hydrogenation of imine obtained by reaction of AMF with aniline showed that Pt-based catalysts (both Pt/Al2O3 and Pt/C) are highly active and provide high selectivity and stability, while Pd and Au nanoparticles supported on γ-alumina and carbon show low selectivity. A wide range of N-substituted 5-(acetoxymethyl)-2-furfuryl amines was synthesized in good to excellent yields using Pt/Al2O3 catalyst and methanol as a solvent.

KW - 5-Acetoxymethylfurfural

KW - Flow hydrogenation

KW - Primary amines

KW - Pt/AlOcatalyst

KW - Reductive amination

KW - Pt/Al(2)O(3)catalyst

KW - HYDROGENATION

KW - AMINES

KW - BIOMASS

KW - ALDEHYDES

KW - UTILITY

UR - http://www.scopus.com/inward/record.url?scp=85097078757&partnerID=8YFLogxK

U2 - 10.1016/j.mcat.2020.111297

DO - 10.1016/j.mcat.2020.111297

M3 - Article

AN - SCOPUS:85097078757

VL - 499

JO - Molecular Catalysis

JF - Molecular Catalysis

SN - 2468-8231

M1 - 111297

ER -

ID: 26203104