Standard

Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity. / Bairqdar, Ahmad; Shakhtshneider, Elena; Ivanoshchuk, Dinara et al.

In: Journal of Personalized Medicine, Vol. 13, No. 10, 1500, 16.10.2023.

Research output: Contribution to journal › Article › peer-review

Harvard

Bairqdar, A, Shakhtshneider, E, Ivanoshchuk, D, Mikhailova, S, Kashtanova, E, Shramko, V, Polonskaya, Y & Ragino, Y 2023, 'Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity', Journal of Personalized Medicine, vol. 13, no. 10, 1500. https://doi.org/10.3390/jpm13101500

APA

Bairqdar, A., Shakhtshneider, E., Ivanoshchuk, D., Mikhailova, S., Kashtanova, E., Shramko, V., Polonskaya, Y., & Ragino, Y. (2023). Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity. Journal of Personalized Medicine, 13(10), [1500]. https://doi.org/10.3390/jpm13101500

Vancouver

Bairqdar A, Shakhtshneider E, Ivanoshchuk D, Mikhailova S, Kashtanova E, Shramko V et al. Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity. Journal of Personalized Medicine. 2023 Oct 16;13(10):1500. doi: 10.3390/jpm13101500

Author

Bairqdar, Ahmad ; Shakhtshneider, Elena ; Ivanoshchuk, Dinara et al. / Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity. In: Journal of Personalized Medicine. 2023 ; Vol. 13, No. 10.

BibTeX

@article{9c9b43c728774795ad63f86df695414e,
title = "Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity",
abstract = "The increase in the prevalence of overweight, obesity and associated diseases is a serious problem. The aim of the study was to identify rare variants in obesity-associated genes in young adults with abdominal obesity in our population and to analyze information about these variants in other populations. Targeted high-throughput sequencing of obesity-associated genes was performed (203 young adults with an abdominal obesity phenotype). In our study, all of the 203 young adults with abdominal obesity had some rare variant in the genes associated with obesity. The widest range of rare and common variants was presented in ADIPOQ, FTO, GLP1R, GHRL, and INS genes. The use of targeted sequencing and clinical criteria makes it possible to identify carriers of rare clinically significant variants in a wide range of obesity-associated genes and to investigate their influence on phenotypic manifestations of abdominal obesity.",
author = "Ahmad Bairqdar and Elena Shakhtshneider and Dinara Ivanoshchuk and Svetlana Mikhailova and Elena Kashtanova and Viktoriya Shramko and Yana Polonskaya and Yuliya Ragino",
note = "The work was carried out within the framework of Russian Science Foundation, Grant. No. 21-15-00022.",
year = "2023",
month = oct,
day = "16",
doi = "10.3390/jpm13101500",
language = "English",
volume = "13",
journal = "Journal of Personalized Medicine",
issn = "2075-4426",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "10",

}

RIS

TY - JOUR

T1 - Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity

AU - Bairqdar, Ahmad

AU - Shakhtshneider, Elena

AU - Ivanoshchuk, Dinara

AU - Mikhailova, Svetlana

AU - Kashtanova, Elena

AU - Shramko, Viktoriya

AU - Polonskaya, Yana

AU - Ragino, Yuliya

N1 - The work was carried out within the framework of Russian Science Foundation, Grant. No. 21-15-00022.

PY - 2023/10/16

Y1 - 2023/10/16

N2 - The increase in the prevalence of overweight, obesity and associated diseases is a serious problem. The aim of the study was to identify rare variants in obesity-associated genes in young adults with abdominal obesity in our population and to analyze information about these variants in other populations. Targeted high-throughput sequencing of obesity-associated genes was performed (203 young adults with an abdominal obesity phenotype). In our study, all of the 203 young adults with abdominal obesity had some rare variant in the genes associated with obesity. The widest range of rare and common variants was presented in ADIPOQ, FTO, GLP1R, GHRL, and INS genes. The use of targeted sequencing and clinical criteria makes it possible to identify carriers of rare clinically significant variants in a wide range of obesity-associated genes and to investigate their influence on phenotypic manifestations of abdominal obesity.

AB - The increase in the prevalence of overweight, obesity and associated diseases is a serious problem. The aim of the study was to identify rare variants in obesity-associated genes in young adults with abdominal obesity in our population and to analyze information about these variants in other populations. Targeted high-throughput sequencing of obesity-associated genes was performed (203 young adults with an abdominal obesity phenotype). In our study, all of the 203 young adults with abdominal obesity had some rare variant in the genes associated with obesity. The widest range of rare and common variants was presented in ADIPOQ, FTO, GLP1R, GHRL, and INS genes. The use of targeted sequencing and clinical criteria makes it possible to identify carriers of rare clinically significant variants in a wide range of obesity-associated genes and to investigate their influence on phenotypic manifestations of abdominal obesity.

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85175456691&origin=inward&txGid=06c60f4896e7132ed5f467904f8caf2e

U2 - 10.3390/jpm13101500

DO - 10.3390/jpm13101500

M3 - Article

C2 - 37888112

VL - 13

JO - Journal of Personalized Medicine

JF - Journal of Personalized Medicine

SN - 2075-4426

IS - 10

M1 - 1500

ER -

ID: 57515660