TY - JOUR

T1 - Problems of comprehensive chemical profiling of medicinal plants

AU - Morozov, S. V.

AU - Tkacheva, N. I.

AU - Tkachev, A. V.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Interest and attention to phytotherapy in Russia are increasing every year, which is consistent with global trends. Ensuring the growing demand inevitably leads to the appearance of phytopreparations of low quality and efficiency, and sometimes to a complete falsification of plant raw materials and preparations from it. Therefore, the pharmaceutical safety and quality of plant raw materials, herbal preparations and medicines from plant raw materials are among the most important problems in the field of medicine, biomedicine, pharmacognosy and phytochemistry. The review considers modern methodological approaches to solving problems of the problems mentioned, various concepts of identification, evaluation of the authenticity and quality control of herbal medicines using markers of various types and instrumental methods of chromatographic profiling (one of the methods of metabolic research) of plant compositions, spectral and hyphenated methods used to solve these problems, the issues of standardization of plant raw materials, drugs in and medicines based on it, the world experience in solving problems of assessing the quality of plant raw materials and phytopreparations and the state of research in Russia.

AB - Interest and attention to phytotherapy in Russia are increasing every year, which is consistent with global trends. Ensuring the growing demand inevitably leads to the appearance of phytopreparations of low quality and efficiency, and sometimes to a complete falsification of plant raw materials and preparations from it. Therefore, the pharmaceutical safety and quality of plant raw materials, herbal preparations and medicines from plant raw materials are among the most important problems in the field of medicine, biomedicine, pharmacognosy and phytochemistry. The review considers modern methodological approaches to solving problems of the problems mentioned, various concepts of identification, evaluation of the authenticity and quality control of herbal medicines using markers of various types and instrumental methods of chromatographic profiling (one of the methods of metabolic research) of plant compositions, spectral and hyphenated methods used to solve these problems, the issues of standardization of plant raw materials, drugs in and medicines based on it, the world experience in solving problems of assessing the quality of plant raw materials and phytopreparations and the state of research in Russia.

KW - Chemical markers

KW - Chromatographic profiles

KW - Identification

KW - Medicinal plants

KW - Metabolomics

KW - Pharmaceutical safety

KW - Pharmacognosy

KW - Spectral profiles

UR - http://www.scopus.com/inward/record.url?scp=85061579330&partnerID=8YFLogxK

U2 - 10.14258/jcprm.2018044003

DO - 10.14258/jcprm.2018044003

M3 - Article

AN - SCOPUS:85061579330

VL - 21

SP - 5

EP - 28

JO - Turczaninowia

JF - Turczaninowia

SN - 1560-7259

IS - 4

ER -