Research output: Contribution to journal › Review article › peer-review
Precision nomenclature for the new genomics. / Lewin, Harris A.; Graves, Jennifer A.Marshall; Ryder, Oliver A. et al.
In: GigaScience, Vol. 8, No. 8, giz086, 01.08.2019.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - Precision nomenclature for the new genomics
AU - Lewin, Harris A.
AU - Graves, Jennifer A.Marshall
AU - Ryder, Oliver A.
AU - Graphodatsky, Alexander S.
AU - O'Brien, Stephen J.
N1 - © The Author(s) 2019. Published by Oxford University Press.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images of all chromosomes of an organism or species). As large-scale sequencing projects progress, adoption of this nomenclature will assist end users to properly classify genome assemblies, thus facilitating genomic analysis.
AB - The confluence of two scientific disciplines may lead to nomenclature conflicts that require new terms while respecting historical definitions. This is the situation with the current state of cytology and genomics, which offer examples of distinct nomenclature and vocabularies that require reconciliation. In this article, we propose the new terms C-scaffold (for chromosome-scale assemblies of sequenced DNA fragments, commonly named scaffolds) and scaffotype (the resulting collection of C-scaffolds that represent an organism's genome). This nomenclature avoids conflict with the historical definitions of the terms chromosome (a microscopic body made of DNA and protein) and karyotype (the collection of images of all chromosomes of an organism or species). As large-scale sequencing projects progress, adoption of this nomenclature will assist end users to properly classify genome assemblies, thus facilitating genomic analysis.
UR - http://www.scopus.com/inward/record.url?scp=85071515417&partnerID=8YFLogxK
U2 - 10.1093/gigascience/giz086
DO - 10.1093/gigascience/giz086
M3 - Review article
C2 - 31437278
AN - SCOPUS:85071515417
VL - 8
JO - GigaScience
JF - GigaScience
SN - 2047-217X
IS - 8
M1 - giz086
ER -
ID: 21451741