Research output: Contribution to journal › Article › peer-review
Pharmacoeconomic evaluation of insulin therapy in children with type 1 diabetes mellitus, based on real-world clinical data. / Grazhdankina, Alexandra A.; Karakulova, Elena V.; Koshmeleva, Marina V. et al.
In: Vestnik Sovremennoi Klinicheskoi Mediciny, Vol. 18, No. 5, 4, 2025, p. 37-46.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Pharmacoeconomic evaluation of insulin therapy in children with type 1 diabetes mellitus, based on real-world clinical data
AU - Grazhdankina, Alexandra A.
AU - Karakulova, Elena V.
AU - Koshmeleva, Marina V.
AU - Samoylova, Yulia G.
N1 - Grazhdankina, A.A.; Karakulova, E.V.; Koshmeleva, M.V.; Samoylova Yu.G. Pharmacoeconomic evaluation of insulin therapy in children with type 1 diabetes mellitus, based on real-world clinical data. The Bulletin of Contemporary Clinical Medicine. 2025, 18 (5), 37-46. DOI: 10.20969/VSKM.2025.18(5).37-46.
PY - 2025
Y1 - 2025
N2 - Introduction. Use of insulin pumps and continuous glucose monitoring systems has been shown to improve the control of type 1 diabetes mellitus in children, but these technologies require significant costs for the healthcare system. Aim. To assess the cost-effectiveness of various insulin therapy regimens in children with type 1 diabetes mellitus, based on real-world clinical data. Materials and Methods. Cost-effectiveness was analyzed using data from the Federal Register of Diabetes Mellitus in the Tomsk Region for the years 2022-2024 (328 children). Results and Discussion. Number of children receiving insulin pump therapy increased 2.5-fold during the study period, which led to an increase in the total treatment costs from 6 million to 15.3 million Russian rubles, primarily due to the increased costs in the Preferential Drug Provision System. At the same time, the target HbA1c level of
AB - Introduction. Use of insulin pumps and continuous glucose monitoring systems has been shown to improve the control of type 1 diabetes mellitus in children, but these technologies require significant costs for the healthcare system. Aim. To assess the cost-effectiveness of various insulin therapy regimens in children with type 1 diabetes mellitus, based on real-world clinical data. Materials and Methods. Cost-effectiveness was analyzed using data from the Federal Register of Diabetes Mellitus in the Tomsk Region for the years 2022-2024 (328 children). Results and Discussion. Number of children receiving insulin pump therapy increased 2.5-fold during the study period, which led to an increase in the total treatment costs from 6 million to 15.3 million Russian rubles, primarily due to the increased costs in the Preferential Drug Provision System. At the same time, the target HbA1c level of
KW - continuous glucose monitoring
KW - cost-effectiveness analysis
KW - insulin pump
KW - modeling
KW - multiple daily injections
KW - sensitivity analysis
KW - МНОГОКРАТНЫЕ ИНЪЕКЦИИ ИНСУЛИНА
KW - ИНСУЛИНОВАЯ ПОМПА
KW - НЕПРЕРЫВНЫЙ МОНИТОРИНГ ГЛЮКОЗЫ
KW - КЛИНИКО-ЭКОНОМИЧЕСКИЙ АНАЛИЗ
KW - МОДЕЛИРОВАНИЕ
KW - АНАЛИЗ ЧУВСТВИТЕЛЬНОСТИ
UR - https://www.scopus.com/pages/publications/105020831958
UR - https://elibrary.ru/item.asp?id=83144924
UR - https://www.mendeley.com/catalogue/12f28952-8e8f-3524-9fea-7e2d4eb0a1c3/
U2 - 10.20969/VSKM.2025.18(5).37-46
DO - 10.20969/VSKM.2025.18(5).37-46
M3 - Article
VL - 18
SP - 37
EP - 46
JO - Вестник современной клинической медицины
JF - Вестник современной клинической медицины
SN - 2071-0240
IS - 5
M1 - 4
ER -
ID: 72671431