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Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast. / Autenshlyus, A. I.; Golovanova, A. V.; Studenikina, A. A. et al.

In: Doklady Biochemistry and Biophysics, Vol. 484, No. 1, 01.05.2019, p. 59-62.

Research output: Contribution to journal › Article › peer-review

Harvard

Autenshlyus, AI, Golovanova, AV, Studenikina, AA, Brusentsov, II, Proskura, AV, Zhurakovskiy, IP, Arkhipov, SA, Sidorov, SV, Vavilin, VA & Lyakhovich, VV 2019, 'Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast', Doklady Biochemistry and Biophysics, vol. 484, no. 1, pp. 59-62. https://doi.org/10.1134/S1607672919010162

APA

Autenshlyus, A. I., Golovanova, A. V., Studenikina, A. A., Brusentsov, I. I., Proskura, A. V., Zhurakovskiy, I. P., Arkhipov, S. A., Sidorov, S. V., Vavilin, V. A., & Lyakhovich, V. V. (2019). Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast. Doklady Biochemistry and Biophysics, 484(1), 59-62. https://doi.org/10.1134/S1607672919010162

Vancouver

Autenshlyus AI, Golovanova AV, Studenikina AA, Brusentsov II, Proskura AV, Zhurakovskiy IP et al. Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast. Doklady Biochemistry and Biophysics. 2019 May 1;484(1):59-62. doi: 10.1134/S1607672919010162

Author

Autenshlyus, A. I. ; Golovanova, A. V. ; Studenikina, A. A. et al. / Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast. In: Doklady Biochemistry and Biophysics. 2019 ; Vol. 484, No. 1. pp. 59-62.

BibTeX

@article{d145fbaca11d4a63b69ed7ff02c95289,
title = "Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast",
abstract = "Abstract: Biopsy material of patients with malignant and benign breast diseases was examined. HRG mRNA expression was detected in 70% of cases in biopsy material obtained from patients with nonspecific invasive carcinoma and in 66.7% of cases in biopsy material of patients with benign breast diseases. Immunohistochemical analysis revealed expression of collagen II, the beta-1 integrin, and E-cadherin—markers of epithelial–mesenchymal transition. The use of RT-qPCR combined with immunohistochemical study made it possible to identify atypical cells, which can be regarded as precancerous changes, in individual patients.",
keywords = "EPITHELIAL-MESENCHYMAL TRANSITION, CANCER, Cadherins/biosynthesis, Humans, Middle Aged, Gene Expression Regulation, Neoplastic, Proteins/genetics, Antigens, CD/biosynthesis, Neoplasm Proteins/biosynthesis, Adolescent, Epithelial-Mesenchymal Transition, Adult, Female, Aged, Breast Neoplasms/genetics, Biomarkers, Tumor/biosynthesis",
author = "Autenshlyus, {A. I.} and Golovanova, {A. V.} and Studenikina, {A. A.} and Brusentsov, {I. I.} and Proskura, {A. V.} and Zhurakovskiy, {I. P.} and Arkhipov, {S. A.} and Sidorov, {S. V.} and Vavilin, {V. A.} and Lyakhovich, {V. V.}",
year = "2019",
month = may,
day = "1",
doi = "10.1134/S1607672919010162",
language = "English",
volume = "484",
pages = "59--62",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "1",

}

RIS

TY - JOUR

T1 - Personalized Approach to Assessing mRNA Expression of Histidine-Rich Glycoprotein and Immunohistochemical Markers in Diseases of the Breast

AU - Autenshlyus, A. I.

AU - Golovanova, A. V.

AU - Studenikina, A. A.

AU - Brusentsov, I. I.

AU - Proskura, A. V.

AU - Zhurakovskiy, I. P.

AU - Arkhipov, S. A.

AU - Sidorov, S. V.

AU - Vavilin, V. A.

AU - Lyakhovich, V. V.

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Abstract: Biopsy material of patients with malignant and benign breast diseases was examined. HRG mRNA expression was detected in 70% of cases in biopsy material obtained from patients with nonspecific invasive carcinoma and in 66.7% of cases in biopsy material of patients with benign breast diseases. Immunohistochemical analysis revealed expression of collagen II, the beta-1 integrin, and E-cadherin—markers of epithelial–mesenchymal transition. The use of RT-qPCR combined with immunohistochemical study made it possible to identify atypical cells, which can be regarded as precancerous changes, in individual patients.

AB - Abstract: Biopsy material of patients with malignant and benign breast diseases was examined. HRG mRNA expression was detected in 70% of cases in biopsy material obtained from patients with nonspecific invasive carcinoma and in 66.7% of cases in biopsy material of patients with benign breast diseases. Immunohistochemical analysis revealed expression of collagen II, the beta-1 integrin, and E-cadherin—markers of epithelial–mesenchymal transition. The use of RT-qPCR combined with immunohistochemical study made it possible to identify atypical cells, which can be regarded as precancerous changes, in individual patients.

KW - EPITHELIAL-MESENCHYMAL TRANSITION

KW - CANCER

KW - Cadherins/biosynthesis

KW - Humans

KW - Middle Aged

KW - Gene Expression Regulation, Neoplastic

KW - Proteins/genetics

KW - Antigens, CD/biosynthesis

KW - Neoplasm Proteins/biosynthesis

KW - Adolescent

KW - Epithelial-Mesenchymal Transition

KW - Adult

KW - Female

KW - Aged

KW - Breast Neoplasms/genetics

KW - Biomarkers, Tumor/biosynthesis

UR - http://www.scopus.com/inward/record.url?scp=85064830947&partnerID=8YFLogxK

U2 - 10.1134/S1607672919010162

DO - 10.1134/S1607672919010162

M3 - Article

C2 - 31012015

AN - SCOPUS:85064830947

VL - 484

SP - 59

EP - 62

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 19629114