Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging

Standard

Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging : Application for oximetry in tumors. / Gorodetskii, Artem A.; Eubank, Timothy D.; Driesschaert, Benoit et al.

In: Journal of Magnetic Resonance, Vol. 297, 01.12.2018, p. 42-50.

Research output: Contribution to journal › Article › peer-review

Harvard

Gorodetskii, AA, Eubank, TD, Driesschaert, B, Poncelet, M, Ellis, E, Khramtsov, VV & Bobko, AA 2018, 'Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging: Application for oximetry in tumors', Journal of Magnetic Resonance, vol. 297, pp. 42-50. https://doi.org/10.1016/j.jmr.2018.10.005

APA

Gorodetskii, A. A., Eubank, T. D., Driesschaert, B., Poncelet, M., Ellis, E., Khramtsov, V. V., & Bobko, A. A. (2018). Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging: Application for oximetry in tumors. Journal of Magnetic Resonance, 297, 42-50. https://doi.org/10.1016/j.jmr.2018.10.005

Vancouver

Gorodetskii AA, Eubank TD, Driesschaert B, Poncelet M, Ellis E, Khramtsov VV et al. Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging: Application for oximetry in tumors. Journal of Magnetic Resonance. 2018 Dec 1;297:42-50. doi: 10.1016/j.jmr.2018.10.005

Author

Gorodetskii, Artem A. ; Eubank, Timothy D. ; Driesschaert, Benoit et al. / Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging : Application for oximetry in tumors. In: Journal of Magnetic Resonance. 2018 ; Vol. 297. pp. 42-50.

BibTeX

@article{19e44812acfc4856a5729a50113b2ba1,

title = "Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging: Application for oximetry in tumors",

abstract = "Overhauser-enhanced Magnetic Resonance Imaging (OMRI) is a double resonance technique applied for oxygen imaging in aqueous samples and biological tissues. In this report, we present an improved OMRI approach of oxygen measurement using the single line “Finland” trityl spin probe. Compared to a traditional approach, we introduced an additional mechanism of leakage of spin polarization due to an interaction of a spin system with oxygen. The experimental comparison of the new approach with an oxygen-dependent leakage factor to a traditional approach performed in phantom samples in vitro, and mouse tumor model in vivo, shows improved accuracy of determination of oxygen and contrast agent concentrations.",

keywords = "Leakage of spin polarization, Overhauser-enhanced magnetic resonance imaging (OMRI), Oximetry, Proton-electron double-resonance imaging (PEDRI), Trityl radical, Tumor tissue oximetry, MRI, EPR, LATTICE-RELAXATION, PO(2), OXYMETRY, COREGISTRATION, BOLD",

author = "Gorodetskii, {Artem A.} and Eubank, {Timothy D.} and Benoit Driesschaert and Martin Poncelet and Emily Ellis and Khramtsov, {Valery V.} and Bobko, {Andrey A.}",

year = "2018",

month = dec,

day = "1",

doi = "10.1016/j.jmr.2018.10.005",

language = "English",

volume = "297",

pages = "42--50",

journal = "Journal of Magnetic Resonance",

issn = "1090-7807",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Oxygen-induced leakage of spin polarization in Overhauser-enhanced magnetic resonance imaging

T2 - Application for oximetry in tumors

AU - Gorodetskii, Artem A.

AU - Eubank, Timothy D.

AU - Driesschaert, Benoit

AU - Poncelet, Martin

AU - Ellis, Emily

AU - Khramtsov, Valery V.

AU - Bobko, Andrey A.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Overhauser-enhanced Magnetic Resonance Imaging (OMRI) is a double resonance technique applied for oxygen imaging in aqueous samples and biological tissues. In this report, we present an improved OMRI approach of oxygen measurement using the single line “Finland” trityl spin probe. Compared to a traditional approach, we introduced an additional mechanism of leakage of spin polarization due to an interaction of a spin system with oxygen. The experimental comparison of the new approach with an oxygen-dependent leakage factor to a traditional approach performed in phantom samples in vitro, and mouse tumor model in vivo, shows improved accuracy of determination of oxygen and contrast agent concentrations.

AB - Overhauser-enhanced Magnetic Resonance Imaging (OMRI) is a double resonance technique applied for oxygen imaging in aqueous samples and biological tissues. In this report, we present an improved OMRI approach of oxygen measurement using the single line “Finland” trityl spin probe. Compared to a traditional approach, we introduced an additional mechanism of leakage of spin polarization due to an interaction of a spin system with oxygen. The experimental comparison of the new approach with an oxygen-dependent leakage factor to a traditional approach performed in phantom samples in vitro, and mouse tumor model in vivo, shows improved accuracy of determination of oxygen and contrast agent concentrations.

KW - Leakage of spin polarization

KW - Overhauser-enhanced magnetic resonance imaging (OMRI)

KW - Oximetry

KW - Proton-electron double-resonance imaging (PEDRI)

KW - Trityl radical

KW - Tumor tissue oximetry

KW - MRI

KW - EPR

KW - LATTICE-RELAXATION

KW - PO(2)

KW - OXYMETRY

KW - COREGISTRATION

KW - BOLD

UR - http://www.scopus.com/inward/record.url?scp=85055210775&partnerID=8YFLogxK

U2 - 10.1016/j.jmr.2018.10.005

DO - 10.1016/j.jmr.2018.10.005

M3 - Article

C2 - 30359906

AN - SCOPUS:85055210775

VL - 297

SP - 42

EP - 50

JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

SN - 1090-7807

ER -

ID: 17248114