Research output: Contribution to journal › Article › peer-review
One-pot synthesis of fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes. / Politanskaya, Larisa; Wang, Jiaying; Troshkova, Nadezhda et al.
In: Journal of Fluorine Chemistry, Vol. 263, 110045, 11.2022.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - One-pot synthesis of fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes
AU - Politanskaya, Larisa
AU - Wang, Jiaying
AU - Troshkova, Nadezhda
AU - Chuikov, Igor
AU - Bagryanskaya, Irina
N1 - Funding Information: The authors thank the Multi-Access Chemical Service Center SB RAS for spectral and analytical measurements, and Ministry of Science and Higher Education of the Russian Federation (Project FWUE-2022-0002) for financial support. Publisher Copyright: © 2022
PY - 2022/11
Y1 - 2022/11
N2 - A facile p-toluenesulfonic acid–catalyzed one-pot synthesis of biologically interesting fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes is described. This synthetic method is metal-free, operationally simple, cheap and productive. It provides a rapid access to the title compounds as well as their 3-benzylidene and 8-cinnamoyl derivatives, that are of interest as objects for the evaluation of their pharmacological properties.
AB - A facile p-toluenesulfonic acid–catalyzed one-pot synthesis of biologically interesting fluorinated 2-arylchroman-4-one derivatives from 2-(triisopropylsilyl)ethynylphenols and aromatic aldehydes is described. This synthetic method is metal-free, operationally simple, cheap and productive. It provides a rapid access to the title compounds as well as their 3-benzylidene and 8-cinnamoyl derivatives, that are of interest as objects for the evaluation of their pharmacological properties.
KW - cycloaddition
KW - fluorinated flavanones
KW - hydration reaction
KW - NMR analysis
KW - p-toluenesulfonic acid
KW - TIPS-ethynylphenols
UR - http://www.scopus.com/inward/record.url?scp=85144133682&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/dfa894c7-b26d-38b2-8998-9ac30d965303/
U2 - 10.1016/j.jfluchem.2022.110045
DO - 10.1016/j.jfluchem.2022.110045
M3 - Article
AN - SCOPUS:85144133682
VL - 263
JO - Journal of Fluorine Chemistry
JF - Journal of Fluorine Chemistry
SN - 0022-1139
M1 - 110045
ER -
ID: 41209389