Research output: Contribution to journal › Article › peer-review
On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms. / Parshin, D. V.; Kuyanova, Yu O.; Kislitsin, D. S. et al.
In: Journal of Applied Mechanics and Technical Physics, Vol. 59, No. 6, 01.11.2018, p. 963-970.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - On the Impact of Flow-Diverters on the Hemodynamics of Human Cerebral Aneurysms
AU - Parshin, D. V.
AU - Kuyanova, Yu O.
AU - Kislitsin, D. S.
AU - Windberger, U.
AU - Chupakhin, A. P.
N1 - Publisher Copyright: © 2018, Pleiades Publishing, Inc.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.
AB - The impact of flow-diverters used for cerebral aneurysm treatment on human brain hemodynamics was evaluated qualitatively and quantitatively. Numerical simulation of flow-diverter placement in cerebral vessels with aneurysms was carried out for the case history of a real patient using the commercial ANSYS 17.2 package with different (Newtonian and non-Newtonian) hydrodynamic models for blood rheology in different parts of the vessel and aneurysm, which is due to experimental data. It is shown that after flow-diverter placement, the blood flow through the artery segment containing the aneurysm neck decreases, resulting in a redistribution of the cerebral blood flow, which becomes close to the blood flow in healthy subjects. Changes in wall shear stresses in the flow-diverter region are indicative of possible aneurysm recanalization.
KW - brain hemodynamics
KW - cerebral aneurysm
KW - flow-diverter
KW - non-Newtonian blood rheology
KW - reconstruction of DICOM images
UR - http://www.scopus.com/inward/record.url?scp=85059784726&partnerID=8YFLogxK
U2 - 10.1134/S0021894418060019
DO - 10.1134/S0021894418060019
M3 - Article
AN - SCOPUS:85059784726
VL - 59
SP - 963
EP - 970
JO - Journal of Applied Mechanics and Technical Physics
JF - Journal of Applied Mechanics and Technical Physics
SN - 0021-8944
IS - 6
ER -
ID: 18119339