Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position

Novel derivatives of deoxycholic acid bearing aliphatic or cyclic diamine moieties at the C-3 position: Synthesis and evaluation of anti-proliferative activity

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	3755-3759
Number of pages	5
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	27
Issue number	16
DOIs	https://doi.org/10.1016/j.bmcl.2017.06.072
Publication status	Published - 15 Aug 2017

Anti-proliferative activity, Cytotoxicity, Deoxycholic acid derivatives, Diamines, Epoxides, Humans, Diamines/chemical synthesis, Structure-Activity Relationship, Antineoplastic Agents/chemical synthesis, Dose-Response Relationship, Drug, Cell Line, Tumor, Molecular Structure, Cell Proliferation/drug effects, Deoxycholic Acid/chemical synthesis, Drug Screening Assays, Antitumor, CHOLIC-ACID, DESIGN, CELL-LINES, CANCER, CHAIN, AGENTS, ANTIMICROBIAL ACTIVITY, BILE-ACIDS, CARBONIC-ANHYDRASE INHIBITORS

ID: 9561011