Research output: Contribution to journal › Review article › peer-review
NMR Hyperpolarization Techniques of Gases. / Barskiy, Danila A.; Coffey, Aaron M.; Nikolaou, Panayiotis et al.
In: Chemistry - A European Journal, Vol. 23, No. 4, 18.01.2017, p. 725-751.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - NMR Hyperpolarization Techniques of Gases
AU - Barskiy, Danila A.
AU - Coffey, Aaron M.
AU - Nikolaou, Panayiotis
AU - Mikhaylov, Dmitry M.
AU - Goodson, Boyd M.
AU - Branca, Rosa T.
AU - Lu, George J.
AU - Shapiro, Mikhail G.
AU - Telkki, Ville Veikko
AU - Zhivonitko, Vladimir V.
AU - Koptyug, Igor V.
AU - Salnikov, Oleg G.
AU - Kovtunov, Kirill V.
AU - Bukhtiyarov, Valerii I.
AU - Rosen, Matthew S.
AU - Barlow, Michael J.
AU - Safavi, Shahideh
AU - Hall, Ian P.
AU - Schröder, Leif
AU - Chekmenev, Eduard Y.
N1 - Publisher Copyright: © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
PY - 2017/1/18
Y1 - 2017/1/18
N2 - Nuclear spin polarization can be significantly increased through the process of hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance (NMR) experiments by 4–8 orders of magnitude. Hyperpolarized gases, unlike liquids and solids, can often be readily separated and purified from the compounds used to mediate the hyperpolarization processes. These pure hyperpolarized gases enabled many novel MRI applications including the visualization of void spaces, imaging of lung function, and remote detection. Additionally, hyperpolarized gases can be dissolved in liquids and can be used as sensitive molecular probes and reporters. This Minireview covers the fundamentals of the preparation of hyperpolarized gases and focuses on selected applications of interest to biomedicine and materials science.
AB - Nuclear spin polarization can be significantly increased through the process of hyperpolarization, leading to an increase in the sensitivity of nuclear magnetic resonance (NMR) experiments by 4–8 orders of magnitude. Hyperpolarized gases, unlike liquids and solids, can often be readily separated and purified from the compounds used to mediate the hyperpolarization processes. These pure hyperpolarized gases enabled many novel MRI applications including the visualization of void spaces, imaging of lung function, and remote detection. Additionally, hyperpolarized gases can be dissolved in liquids and can be used as sensitive molecular probes and reporters. This Minireview covers the fundamentals of the preparation of hyperpolarized gases and focuses on selected applications of interest to biomedicine and materials science.
KW - gas
KW - hyperpolarization
KW - MRI
KW - NMR
KW - propane
KW - Xe-129
KW - WATER-SOLUBLE CRYPTOPHANES
KW - LASER-POLARIZED XENON
KW - SOURCE XE-129 HYPERPOLARIZER
KW - MESOPOROUS MOLECULAR-SIEVES
KW - NUCLEAR-MAGNETIC-RESONANCE
KW - BROWN ADIPOSE-TISSUE
KW - HYDROGEN-INDUCED POLARIZATION
KW - PARAHYDROGEN-INDUCED POLARIZATION
KW - CONTINUOUSLY CIRCULATING FLOW
KW - MULTIDIMENSIONAL LAPLACE NMR
UR - http://www.scopus.com/inward/record.url?scp=85008247459&partnerID=8YFLogxK
U2 - 10.1002/chem.201603884
DO - 10.1002/chem.201603884
M3 - Review article
C2 - 27711999
AN - SCOPUS:85008247459
VL - 23
SP - 725
EP - 751
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
IS - 4
ER -
ID: 10316490