New crystalline betulin-based materials

Standard

New crystalline betulin-based materials : improving betulin solubility via cocrystal formation. / Myz, Svetlana A.; Mikhailovskaya, Anastasiya V.; Mikhailenko, Mikhail A. et al.

In: Materials Today: Proceedings, Vol. 12, 01.01.2019, p. 82-85.

Research output: Contribution to journal › Conference article › peer-review

Harvard

Myz, SA, Mikhailovskaya, AV, Mikhailenko, MA, Bulina, NV, Kuznetsova, SA & Shakhtshneider, TP 2019, 'New crystalline betulin-based materials: improving betulin solubility via cocrystal formation', Materials Today: Proceedings, vol. 12, pp. 82-85. https://doi.org/10.1016/j.matpr.2019.03.069

APA

Myz, S. A., Mikhailovskaya, A. V., Mikhailenko, M. A., Bulina, N. V., Kuznetsova, S. A., & Shakhtshneider, T. P. (2019). New crystalline betulin-based materials: improving betulin solubility via cocrystal formation. Materials Today: Proceedings, 12, 82-85. https://doi.org/10.1016/j.matpr.2019.03.069

Vancouver

Myz SA, Mikhailovskaya AV, Mikhailenko MA, Bulina NV, Kuznetsova SA, Shakhtshneider TP. New crystalline betulin-based materials: improving betulin solubility via cocrystal formation. Materials Today: Proceedings. 2019 Jan 1;12:82-85. doi: 10.1016/j.matpr.2019.03.069

Author

Myz, Svetlana A. ; Mikhailovskaya, Anastasiya V. ; Mikhailenko, Mikhail A. et al. / New crystalline betulin-based materials : improving betulin solubility via cocrystal formation. In: Materials Today: Proceedings. 2019 ; Vol. 12. pp. 82-85.

BibTeX

@article{6fa210ccb1144a2a91153892a6061cf4,

title = "New crystalline betulin-based materials: improving betulin solubility via cocrystal formation",

abstract = "The cocrystal formation potential of betulin with aliphatic dicarboxylic acids was investigated. Carboxylic acids of varying carbon chain length, namely: adipic, succinic and suberic acids, were selected to explore the effect of the coformer structure on cocrystal formation when liquid-assisted grinding was used. Cocrystal formation was characterized by powder XRD and IR studies. Betulin cocrystals with adipic acid were successfully synthesized and HPLC analysis showed that solubility of the betulin cocrystal was significantly improved compared to the initial betulin and its mechanocomposite with polymer.",

keywords = "Betulin, dicarboxylic acids, co-grinding, cocrystals, solubility, Dicarboxylic acids, Solubility, Co-grinding, Cocrystals",

author = "Myz, {Svetlana A.} and Mikhailovskaya, {Anastasiya V.} and Mikhailenko, {Mikhail A.} and Bulina, {Natalia V.} and Kuznetsova, {Svetlana A.} and Shakhtshneider, {Tatyana P.}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd. All rights reserved.; 5th International Conference on Fundamental Bases of Mechanochemical Technologies (FBMT) ; Conference date: 25-06-2018 Through 28-06-2018",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/j.matpr.2019.03.069",

language = "English",

volume = "12",

pages = "82--85",

journal = "Materials Today: Proceedings",

issn = "2214-7853",

publisher = "Elsevier Science B.V.",

}

RIS

TY - JOUR

T1 - New crystalline betulin-based materials

T2 - 5th International Conference on Fundamental Bases of Mechanochemical Technologies (FBMT)

AU - Myz, Svetlana A.

AU - Mikhailovskaya, Anastasiya V.

AU - Mikhailenko, Mikhail A.

AU - Bulina, Natalia V.

AU - Kuznetsova, Svetlana A.

AU - Shakhtshneider, Tatyana P.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - The cocrystal formation potential of betulin with aliphatic dicarboxylic acids was investigated. Carboxylic acids of varying carbon chain length, namely: adipic, succinic and suberic acids, were selected to explore the effect of the coformer structure on cocrystal formation when liquid-assisted grinding was used. Cocrystal formation was characterized by powder XRD and IR studies. Betulin cocrystals with adipic acid were successfully synthesized and HPLC analysis showed that solubility of the betulin cocrystal was significantly improved compared to the initial betulin and its mechanocomposite with polymer.

AB - The cocrystal formation potential of betulin with aliphatic dicarboxylic acids was investigated. Carboxylic acids of varying carbon chain length, namely: adipic, succinic and suberic acids, were selected to explore the effect of the coformer structure on cocrystal formation when liquid-assisted grinding was used. Cocrystal formation was characterized by powder XRD and IR studies. Betulin cocrystals with adipic acid were successfully synthesized and HPLC analysis showed that solubility of the betulin cocrystal was significantly improved compared to the initial betulin and its mechanocomposite with polymer.

KW - Betulin

KW - dicarboxylic acids

KW - co-grinding

KW - cocrystals

KW - solubility

KW - Dicarboxylic acids

KW - Solubility

KW - Co-grinding

KW - Cocrystals

UR - http://www.scopus.com/inward/record.url?scp=85080144503&partnerID=8YFLogxK

U2 - 10.1016/j.matpr.2019.03.069

DO - 10.1016/j.matpr.2019.03.069

M3 - Conference article

VL - 12

SP - 82

EP - 85

JO - Materials Today: Proceedings

JF - Materials Today: Proceedings

SN - 2214-7853

Y2 - 25 June 2018 through 28 June 2018

ER -

ID: 23397271