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Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico. / Klyshnikov, K. U.; Ovcharenko, E. A.; Borisov, V. G. et al.

In: Mathematical Biology and Bioinformatics, Vol. 12, No. 2, 2017, p. 559-569.

Research output: Contribution to journalArticlepeer-review

Harvard

Klyshnikov, KU, Ovcharenko, EA, Borisov, VG, Sizova, IN, Burkov, NN, Batranin, AV, Kudryavtseva, YA, Zaharov, YN & Shokin, YI 2017, 'Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico', Mathematical Biology and Bioinformatics, vol. 12, no. 2, pp. 559-569. https://doi.org/10.17537/2017.12.559

APA

Klyshnikov, K. U., Ovcharenko, E. A., Borisov, V. G., Sizova, I. N., Burkov, N. N., Batranin, A. V., Kudryavtseva, Y. A., Zaharov, Y. N., & Shokin, Y. I. (2017). Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico. Mathematical Biology and Bioinformatics, 12(2), 559-569. https://doi.org/10.17537/2017.12.559

Vancouver

Klyshnikov KU, Ovcharenko EA, Borisov VG, Sizova IN, Burkov NN, Batranin AV et al. Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico. Mathematical Biology and Bioinformatics. 2017;12(2):559-569. doi: 10.17537/2017.12.559

Author

Klyshnikov, K. U. ; Ovcharenko, E. A. ; Borisov, V. G. et al. / Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico. In: Mathematical Biology and Bioinformatics. 2017 ; Vol. 12, No. 2. pp. 559-569.

BibTeX

@article{0f4fbd599e7e437f9ce476a7def56d3c,
title = "Modeling of the hemodynamics of vascular prostheses {"}Kemangiprotez{"} in Silico",
abstract = "The paper describes aspects of the application of numerical simulation of fluid flows in clinical medicine with interventions on the human vascular system. The modeling method used in the study is verified using the data of the doppler sonography of the patient underwent vascular replacement. It was shown that the deviation between the numerical experiment and the clinical data - pressure curves at the inlet and outlet of the studied vessel, is 20%. The obtained quantitative characteristics of the flow: peak systolic velocity, final diastolic velocity, minimum diastolic velocity, resistivity index, pulsatility index, systole/diastole index are comparable between verification and experimental data. Thus, for the proximal site of the clinical vessel the corresponding indices were 96.5 cm/s; 4.5 cm/s; 36.2 cm/s; 1.05; 11.5; 21.3. For simulation, 107.9 cm/s; 4.44 cm/s; 43.9 cm/s; 1.05; 12.0; 24.3. In addition, the work describes the application of tested method in two clinical vascular prostheses {"}KemAngioprotez{"} for the assessment of zones of increased shear stress and, thus, the risk of thrombus formation. It is shown that the distribution of critical zones corresponds to zones of anastomosis between prosthesis segments, which may be a potential location for optimization of the device.",
keywords = "Computer modeling, Doppler sonography, Hydrodynamics, Prosthesis",
author = "Klyshnikov, {K. U.} and Ovcharenko, {E. A.} and Borisov, {V. G.} and Sizova, {I. N.} and Burkov, {N. N.} and Batranin, {A. V.} and Kudryavtseva, {Yu A.} and Zaharov, {Yu N.} and Shokin, {Yu I.}",
year = "2017",
doi = "10.17537/2017.12.559",
language = "English",
volume = "12",
pages = "559--569",
journal = "Mathematical Biology and Bioinformatics",
issn = "1994-6538",
publisher = "Institute of Mathematical Problems of Biology",
number = "2",

}

RIS

TY - JOUR

T1 - Modeling of the hemodynamics of vascular prostheses "Kemangiprotez" in Silico

AU - Klyshnikov, K. U.

AU - Ovcharenko, E. A.

AU - Borisov, V. G.

AU - Sizova, I. N.

AU - Burkov, N. N.

AU - Batranin, A. V.

AU - Kudryavtseva, Yu A.

AU - Zaharov, Yu N.

AU - Shokin, Yu I.

PY - 2017

Y1 - 2017

N2 - The paper describes aspects of the application of numerical simulation of fluid flows in clinical medicine with interventions on the human vascular system. The modeling method used in the study is verified using the data of the doppler sonography of the patient underwent vascular replacement. It was shown that the deviation between the numerical experiment and the clinical data - pressure curves at the inlet and outlet of the studied vessel, is 20%. The obtained quantitative characteristics of the flow: peak systolic velocity, final diastolic velocity, minimum diastolic velocity, resistivity index, pulsatility index, systole/diastole index are comparable between verification and experimental data. Thus, for the proximal site of the clinical vessel the corresponding indices were 96.5 cm/s; 4.5 cm/s; 36.2 cm/s; 1.05; 11.5; 21.3. For simulation, 107.9 cm/s; 4.44 cm/s; 43.9 cm/s; 1.05; 12.0; 24.3. In addition, the work describes the application of tested method in two clinical vascular prostheses "KemAngioprotez" for the assessment of zones of increased shear stress and, thus, the risk of thrombus formation. It is shown that the distribution of critical zones corresponds to zones of anastomosis between prosthesis segments, which may be a potential location for optimization of the device.

AB - The paper describes aspects of the application of numerical simulation of fluid flows in clinical medicine with interventions on the human vascular system. The modeling method used in the study is verified using the data of the doppler sonography of the patient underwent vascular replacement. It was shown that the deviation between the numerical experiment and the clinical data - pressure curves at the inlet and outlet of the studied vessel, is 20%. The obtained quantitative characteristics of the flow: peak systolic velocity, final diastolic velocity, minimum diastolic velocity, resistivity index, pulsatility index, systole/diastole index are comparable between verification and experimental data. Thus, for the proximal site of the clinical vessel the corresponding indices were 96.5 cm/s; 4.5 cm/s; 36.2 cm/s; 1.05; 11.5; 21.3. For simulation, 107.9 cm/s; 4.44 cm/s; 43.9 cm/s; 1.05; 12.0; 24.3. In addition, the work describes the application of tested method in two clinical vascular prostheses "KemAngioprotez" for the assessment of zones of increased shear stress and, thus, the risk of thrombus formation. It is shown that the distribution of critical zones corresponds to zones of anastomosis between prosthesis segments, which may be a potential location for optimization of the device.

KW - Computer modeling

KW - Doppler sonography

KW - Hydrodynamics

KW - Prosthesis

UR - http://www.scopus.com/inward/record.url?scp=85046542549&partnerID=8YFLogxK

U2 - 10.17537/2017.12.559

DO - 10.17537/2017.12.559

M3 - Article

AN - SCOPUS:85046542549

VL - 12

SP - 559

EP - 569

JO - Mathematical Biology and Bioinformatics

JF - Mathematical Biology and Bioinformatics

SN - 1994-6538

IS - 2

ER -

ID: 25314550