Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	32370-32379
Number of pages	10
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	117
Issue number	51
DOIs	https://doi.org/10.1073/pnas.2016158117
Publication status	Published - 22 Dec 2020

Antisense oligonucleotide, DNA modification, Mesyl oligonucleotide, Oncogenic microRNA, Phosphorothioate, HEPATOCYTES, oncogenic microRNA, TRAFFICKING, PROLIFERATION, TOXICITY, CELLULAR UPTAKE, NUCLEIC-ACIDS, DELIVERY, antisense oligonucleotide, phosphorothioate, SIGNALING PATHWAY, mesyl oligonucleotide, HEPATOTOXICITY, DERIVATIVES

ID: 27328879