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Mathematical modeling of the tumor markers network. / Voropaeva, O. F.; Shokin, Yu I.; Nepomnyaschchikh, L. M. et al.

Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 225-229 7361888 (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Harvard

Voropaeva, OF, Shokin, YI, Nepomnyaschchikh, LM & Senchukova, SR 2015, Mathematical modeling of the tumor markers network. in Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015., 7361888, Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015, Institute of Electrical and Electronics Engineers Inc., pp. 225-229, International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015, Novosibirsk, Russian Federation, 28.10.2015. https://doi.org/10.1109/SIBIRCON.2015.7361888

APA

Voropaeva, O. F., Shokin, Y. I., Nepomnyaschchikh, L. M., & Senchukova, S. R. (2015). Mathematical modeling of the tumor markers network. In Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015 (pp. 225-229). [7361888] (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SIBIRCON.2015.7361888

Vancouver

Voropaeva OF, Shokin YI, Nepomnyaschchikh LM, Senchukova SR. Mathematical modeling of the tumor markers network. In Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 225-229. 7361888. (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015). doi: 10.1109/SIBIRCON.2015.7361888

Author

Voropaeva, O. F. ; Shokin, Yu I. ; Nepomnyaschchikh, L. M. et al. / Mathematical modeling of the tumor markers network. Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 225-229 (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015).

BibTeX

@inproceedings{b4ad21a9b9154ec59fd5ead2048132a6,
title = "Mathematical modeling of the tumor markers network",
abstract = "This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.",
keywords = "numerical modeling, p53-Mdm2-network, time delay equations, tumor markers",
author = "Voropaeva, {O. F.} and Shokin, {Yu I.} and Nepomnyaschchikh, {L. M.} and Senchukova, {S. R.}",
year = "2015",
month = dec,
day = "21",
doi = "10.1109/SIBIRCON.2015.7361888",
language = "English",
series = "Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "225--229",
booktitle = "Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015",
address = "United States",
note = "International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015 ; Conference date: 28-10-2015 Through 30-10-2015",

}

RIS

TY - GEN

T1 - Mathematical modeling of the tumor markers network

AU - Voropaeva, O. F.

AU - Shokin, Yu I.

AU - Nepomnyaschchikh, L. M.

AU - Senchukova, S. R.

PY - 2015/12/21

Y1 - 2015/12/21

N2 - This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.

AB - This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.

KW - numerical modeling

KW - p53-Mdm2-network

KW - time delay equations

KW - tumor markers

UR - http://www.scopus.com/inward/record.url?scp=84969232905&partnerID=8YFLogxK

U2 - 10.1109/SIBIRCON.2015.7361888

DO - 10.1109/SIBIRCON.2015.7361888

M3 - Conference contribution

AN - SCOPUS:84969232905

T3 - Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015

SP - 225

EP - 229

BT - Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015

Y2 - 28 October 2015 through 30 October 2015

ER -

ID: 25324766