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Mathematical modeling of the tumor markers network. / Voropaeva, O. F.; Shokin, Yu I.; Nepomnyaschchikh, L. M. et al.
Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 225-229 7361888 (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015).
Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
Harvard
Voropaeva, OF, Shokin, YI, Nepomnyaschchikh, LM & Senchukova, SR 2015,
Mathematical modeling of the tumor markers network. in
Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015., 7361888, Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015, Institute of Electrical and Electronics Engineers Inc., pp. 225-229, International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015, Novosibirsk, Russian Federation,
28.10.2015.
https://doi.org/10.1109/SIBIRCON.2015.7361888
APA
Vancouver
Voropaeva OF, Shokin YI, Nepomnyaschchikh LM, Senchukova SR.
Mathematical modeling of the tumor markers network. In Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 225-229. 7361888. (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015). doi: 10.1109/SIBIRCON.2015.7361888
Author
Voropaeva, O. F. ; Shokin, Yu I. ; Nepomnyaschchikh, L. M. et al. /
Mathematical modeling of the tumor markers network. Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 225-229 (Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015).
BibTeX
@inproceedings{b4ad21a9b9154ec59fd5ead2048132a6,
title = "Mathematical modeling of the tumor markers network",
abstract = "This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.",
keywords = "numerical modeling, p53-Mdm2-network, time delay equations, tumor markers",
author = "Voropaeva, {O. F.} and Shokin, {Yu I.} and Nepomnyaschchikh, {L. M.} and Senchukova, {S. R.}",
year = "2015",
month = dec,
day = "21",
doi = "10.1109/SIBIRCON.2015.7361888",
language = "English",
series = "Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "225--229",
booktitle = "Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015",
address = "United States",
note = "International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015 ; Conference date: 28-10-2015 Through 30-10-2015",
}
RIS
TY - GEN
T1 - Mathematical modeling of the tumor markers network
AU - Voropaeva, O. F.
AU - Shokin, Yu I.
AU - Nepomnyaschchikh, L. M.
AU - Senchukova, S. R.
PY - 2015/12/21
Y1 - 2015/12/21
N2 - This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.
AB - This paper is devoted to a numerical analysis of the solutions of the equations system describing the dynamics of the concentration of p53 and Mdm2 proteins in their interaction. A detailed study of the solutions was made when the mathematical model parameters deviated from the basal values. Within the numerical experiments, the states of the system, such as threat by the uncontrolled apoptotic death of cellules, accelerating the aging processes of organisms and of the excessive suppression of p53-induced apoptosis, which increases the risk of tumors, have been investigated. The mechanism of managing the system under stress conditions has been studied in detail.
KW - numerical modeling
KW - p53-Mdm2-network
KW - time delay equations
KW - tumor markers
UR - http://www.scopus.com/inward/record.url?scp=84969232905&partnerID=8YFLogxK
U2 - 10.1109/SIBIRCON.2015.7361888
DO - 10.1109/SIBIRCON.2015.7361888
M3 - Conference contribution
AN - SCOPUS:84969232905
T3 - Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015
SP - 225
EP - 229
BT - Proceedings - 2015 International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - International Conference on Biomedical Engineering and Computational Technologies, SIBIRCON 2015
Y2 - 28 October 2015 through 30 October 2015
ER -
