Management of Challenging Cardiopulmonary Bypass Separation. / Monaco, Fabrizio; Prima, Ambra Licia Di; Kim, Jun Hyun et al.
In: Journal of Cardiothoracic and Vascular Anesthesia, Vol. 34, No. 6, 06.2020, p. 1622-1635.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - Management of Challenging Cardiopulmonary Bypass Separation
AU - Monaco, Fabrizio
AU - Prima, Ambra Licia Di
AU - Kim, Jun Hyun
AU - Plamondon, Marie Jo
AU - Yavorovskiy, Andrey
AU - Likhvantsev, Valery
AU - Lomivorotov, Vladimir
AU - Hajjar, Ludhmila Abrahão
AU - Landoni, Giovanni
AU - Riha, H.
AU - Farag, A. M.G.A.
AU - Gazivoda, G.
AU - Silva, F. S.
AU - Lei, C.
AU - Bradic, N.
AU - El-Tahan, M. R.
AU - Bukamal, N. A.R.
AU - Sun, L.
AU - Wang, C. Y.
N1 - Publisher Copyright: © 2020 Elsevier Inc. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/6
Y1 - 2020/6
N2 - SEPARATION from cardiopulmonary bypass (CPB) after cardiac surgery is a progressive transition from full mechanical circulatory and respiratory support to spontaneous mechanical activity of the lungs and heart. During the separation phase, measurements of cardiac performance with transesophageal echocardiography (TEE) provide the rationale behind the diagnostic and therapeutic decision-making process. In many cases, it is possible to predict a complex separation from CPB, such as when there is known preoperative left or right ventricular dysfunction, bleeding, hypovolemia, vasoplegia, pulmonary hypertension, or owing to technical complications related to the surgery. Prompt diagnosis and therapeutic decisions regarding mechanical or pharmacologic support have to be made within a few minutes. In fact, a complex separation from CPB if not adequately treated leads to a poor outcome in the vast majority of cases. Unfortunately, no specific criteria defining complex separation from CPB and no management guidelines for these patients currently exist. Taking into account the above considerations, the aim of the present review is to describe the most common scenarios associated with a complex CPB separation and to suggest strategies, pharmacologic agents, and para-corporeal mechanical devices that can be adopted to manage patients with complex separation from CPB. The routine management strategies of complex CPB separation of 17 large cardiac centers from 14 countries in 5 continents will also be described.
AB - SEPARATION from cardiopulmonary bypass (CPB) after cardiac surgery is a progressive transition from full mechanical circulatory and respiratory support to spontaneous mechanical activity of the lungs and heart. During the separation phase, measurements of cardiac performance with transesophageal echocardiography (TEE) provide the rationale behind the diagnostic and therapeutic decision-making process. In many cases, it is possible to predict a complex separation from CPB, such as when there is known preoperative left or right ventricular dysfunction, bleeding, hypovolemia, vasoplegia, pulmonary hypertension, or owing to technical complications related to the surgery. Prompt diagnosis and therapeutic decisions regarding mechanical or pharmacologic support have to be made within a few minutes. In fact, a complex separation from CPB if not adequately treated leads to a poor outcome in the vast majority of cases. Unfortunately, no specific criteria defining complex separation from CPB and no management guidelines for these patients currently exist. Taking into account the above considerations, the aim of the present review is to describe the most common scenarios associated with a complex CPB separation and to suggest strategies, pharmacologic agents, and para-corporeal mechanical devices that can be adopted to manage patients with complex separation from CPB. The routine management strategies of complex CPB separation of 17 large cardiac centers from 14 countries in 5 continents will also be described.
KW - anesthesia
KW - cardiopulmonary bypass
KW - discontinuation
KW - inotropes
KW - intensive care
KW - separation
KW - ventricular dysfunction
KW - weaning
KW - RANDOMIZED-CONTROLLED-TRIAL
KW - LOW EJECTION FRACTION
KW - PULMONARY-HYPERTENSION
KW - HEART-FAILURE
KW - TRANSESOPHAGEAL ECHOCARDIOGRAPHY
KW - INTRAAORTIC BALLOON PUMP
KW - CARDIOGENIC-SHOCK
KW - LOW CARDIAC-OUTPUT
KW - AMERICAN SOCIETY
KW - SYSTOLIC ANTERIOR MOTION
UR - http://www.scopus.com/inward/record.url?scp=85083062834&partnerID=8YFLogxK
U2 - 10.1053/j.jvca.2020.02.038
DO - 10.1053/j.jvca.2020.02.038
M3 - Review article
C2 - 32276758
AN - SCOPUS:85083062834
VL - 34
SP - 1622
EP - 1635
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
SN - 1053-0770
IS - 6
ER -
ID: 23985542