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Lymph nodes morphology as predictor natural and premature aging. / Gorchakova, Olga; Gorchakov, Vladimir; Demchenko, Georgy.

Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020. Institute of Electrical and Electronics Engineers Inc., 2020. p. 170-173 9214771 (Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Harvard

Gorchakova, O, Gorchakov, V & Demchenko, G 2020, Lymph nodes morphology as predictor natural and premature aging. in Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020., 9214771, Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020, Institute of Electrical and Electronics Engineers Inc., pp. 170-173, 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020, Novosibirsk, Russian Federation, 06.07.2020. https://doi.org/10.1109/CSGB51356.2020.9214771

APA

Gorchakova, O., Gorchakov, V., & Demchenko, G. (2020). Lymph nodes morphology as predictor natural and premature aging. In Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020 (pp. 170-173). [9214771] (Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CSGB51356.2020.9214771

Vancouver

Gorchakova O, Gorchakov V, Demchenko G. Lymph nodes morphology as predictor natural and premature aging. In Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020. Institute of Electrical and Electronics Engineers Inc. 2020. p. 170-173. 9214771. (Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020). doi: 10.1109/CSGB51356.2020.9214771

Author

Gorchakova, Olga ; Gorchakov, Vladimir ; Demchenko, Georgy. / Lymph nodes morphology as predictor natural and premature aging. Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020. Institute of Electrical and Electronics Engineers Inc., 2020. pp. 170-173 (Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020).

BibTeX

@inproceedings{59b2a80781f14b03a16fe79b0d8c0161,
title = "Lymph nodes morphology as predictor natural and premature aging",
abstract = "The research purpose is a comparative characteristic of lymph nodes structure at natural (physiological) aging of Wistar rats and premature of OXYS rats. We used a morphological method of a research. Age changes of lymph nodes structure differ at rats of OXYS and Wistar. The age-induced changes of lymphoid tissue of Wistar and OXYS rats differ with type of the immune response and morphological variant of lymph nodes structure. The immune response on humoral type is formed in mesenteric and inguinal lymph nodes, and the immune response on cellular type is formed in the tracheobronchial lymph node. The sizes of compartments of lymph nodes reach the greatest development at three-months age of Wistar rats, but it is not observed at OXYS rats. Lymph nodes compartments undergo involution when aging. We noted reduction of structures of cortical substance, especially lymphoid follicles and a paracortex, and expansion of medullary substance in lymph nodes. Lymph nodes are subject big morphological changes at OXYS rats, than at old rats of Wistar. Observed changes of structure of lymph nodes have the region-dependent character and can be considered as aging predictors with the indication on weakening of a drainage and immune function of lymph nodes.",
keywords = "gerontology, lymph node, OXYS and Wistar rats, premature aging",
author = "Olga Gorchakova and Vladimir Gorchakov and Georgy Demchenko",
note = "Publisher Copyright: {\textcopyright} 2020 IEEE. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.; 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020 ; Conference date: 06-07-2020 Through 10-07-2020",
year = "2020",
month = jul,
doi = "10.1109/CSGB51356.2020.9214771",
language = "English",
series = "Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "170--173",
booktitle = "Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020",
address = "United States",

}

RIS

TY - GEN

T1 - Lymph nodes morphology as predictor natural and premature aging

AU - Gorchakova, Olga

AU - Gorchakov, Vladimir

AU - Demchenko, Georgy

N1 - Publisher Copyright: © 2020 IEEE. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/7

Y1 - 2020/7

N2 - The research purpose is a comparative characteristic of lymph nodes structure at natural (physiological) aging of Wistar rats and premature of OXYS rats. We used a morphological method of a research. Age changes of lymph nodes structure differ at rats of OXYS and Wistar. The age-induced changes of lymphoid tissue of Wistar and OXYS rats differ with type of the immune response and morphological variant of lymph nodes structure. The immune response on humoral type is formed in mesenteric and inguinal lymph nodes, and the immune response on cellular type is formed in the tracheobronchial lymph node. The sizes of compartments of lymph nodes reach the greatest development at three-months age of Wistar rats, but it is not observed at OXYS rats. Lymph nodes compartments undergo involution when aging. We noted reduction of structures of cortical substance, especially lymphoid follicles and a paracortex, and expansion of medullary substance in lymph nodes. Lymph nodes are subject big morphological changes at OXYS rats, than at old rats of Wistar. Observed changes of structure of lymph nodes have the region-dependent character and can be considered as aging predictors with the indication on weakening of a drainage and immune function of lymph nodes.

AB - The research purpose is a comparative characteristic of lymph nodes structure at natural (physiological) aging of Wistar rats and premature of OXYS rats. We used a morphological method of a research. Age changes of lymph nodes structure differ at rats of OXYS and Wistar. The age-induced changes of lymphoid tissue of Wistar and OXYS rats differ with type of the immune response and morphological variant of lymph nodes structure. The immune response on humoral type is formed in mesenteric and inguinal lymph nodes, and the immune response on cellular type is formed in the tracheobronchial lymph node. The sizes of compartments of lymph nodes reach the greatest development at three-months age of Wistar rats, but it is not observed at OXYS rats. Lymph nodes compartments undergo involution when aging. We noted reduction of structures of cortical substance, especially lymphoid follicles and a paracortex, and expansion of medullary substance in lymph nodes. Lymph nodes are subject big morphological changes at OXYS rats, than at old rats of Wistar. Observed changes of structure of lymph nodes have the region-dependent character and can be considered as aging predictors with the indication on weakening of a drainage and immune function of lymph nodes.

KW - gerontology

KW - lymph node

KW - OXYS and Wistar rats

KW - premature aging

UR - http://www.scopus.com/inward/record.url?scp=85094818512&partnerID=8YFLogxK

UR - https://elibrary.ru/item.asp?id=45205805

U2 - 10.1109/CSGB51356.2020.9214771

DO - 10.1109/CSGB51356.2020.9214771

M3 - Conference contribution

AN - SCOPUS:85094818512

T3 - Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020

SP - 170

EP - 173

BT - Proceedings - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2020 Cognitive Sciences, Genomics and Bioinformatics, CSGB 2020

Y2 - 6 July 2020 through 10 July 2020

ER -

ID: 26001540