Research output: Contribution to journal › Article › peer-review
Isolation and characterization of exosomes from blood plasma of breast cancer and colorectal cancer patients. / Tamkovich, S. N.; Yunusova, N. V.; Stakheeva, M. N. et al.
In: Biomeditsinskaya Khimiya, Vol. 63, No. 2, 03.2017, p. 165-169.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Isolation and characterization of exosomes from blood plasma of breast cancer and colorectal cancer patients
AU - Tamkovich, S. N.
AU - Yunusova, N. V.
AU - Stakheeva, M. N.
AU - Somov, A. K.
AU - Frolova, A. Y.
AU - Kirushina, N. A.
AU - Afanasyev, S. G.
AU - Grigoryeva, A. E.
AU - Laktionov, P. P.
AU - Kondakova, I. V.
PY - 2017/3
Y1 - 2017/3
N2 - A simple approach for isolation of exosomes from the blood plasma, which allows to obtain highly purified preparations of microvesicles no larger than 100 nm has been proposed. The presence of different subpopulations of exosomes in the blood plasma of healthy donors and cancer patients has been recognized. We found the presence of the universal markers CD9, CD24 and CD81 on exosomes isolated from blood plasma that can be used to their routine typing.
AB - A simple approach for isolation of exosomes from the blood plasma, which allows to obtain highly purified preparations of microvesicles no larger than 100 nm has been proposed. The presence of different subpopulations of exosomes in the blood plasma of healthy donors and cancer patients has been recognized. We found the presence of the universal markers CD9, CD24 and CD81 on exosomes isolated from blood plasma that can be used to their routine typing.
KW - Breast cancer
KW - Colorectal cancer
KW - Exosomes
KW - Flow cytometry
KW - Transmission electron microscopy
KW - Biomarkers/blood
KW - Breast Neoplasms/blood
KW - CD24 Antigen/blood
KW - Case-Control Studies
KW - Colorectal Neoplasms/blood
KW - Exosomes/chemistry
KW - Female
KW - Gene Expression
KW - Humans
KW - Male
KW - Middle Aged
KW - Tetraspanin 28/blood
KW - Tetraspanin 29/blood
UR - http://www.scopus.com/inward/record.url?scp=85027036050&partnerID=8YFLogxK
U2 - 10.18097/PBMC20176302165
DO - 10.18097/PBMC20176302165
M3 - Article
C2 - 28414289
AN - SCOPUS:85027036050
VL - 63
SP - 165
EP - 169
JO - Biomeditsinskaya Khimiya
JF - Biomeditsinskaya Khimiya
SN - 2310-6905
IS - 2
ER -
ID: 9966722