Isoforms of base excision repair enzymes produced by alternative splicing

Standard

Isoforms of base excision repair enzymes produced by alternative splicing. / Boldinova, Elizaveta O.; Khairullin, Rafil F.; Makarova, Alena V. et al.

In: International Journal of Molecular Sciences, Vol. 20, No. 13, 3279, 03.07.2019.

Research output: Contribution to journal › Review article › peer-review

Harvard

Boldinova, EO, Khairullin, RF, Makarova, AV & Zharkov, DO 2019, 'Isoforms of base excision repair enzymes produced by alternative splicing', International Journal of Molecular Sciences, vol. 20, no. 13, 3279. https://doi.org/10.3390/ijms20133279

APA

Boldinova, E. O., Khairullin, R. F., Makarova, A. V., & Zharkov, D. O. (2019). Isoforms of base excision repair enzymes produced by alternative splicing. International Journal of Molecular Sciences, 20(13), [3279]. https://doi.org/10.3390/ijms20133279

Vancouver

Boldinova EO, Khairullin RF, Makarova AV, Zharkov DO. Isoforms of base excision repair enzymes produced by alternative splicing. International Journal of Molecular Sciences. 2019 Jul 3;20(13):3279. doi: 10.3390/ijms20133279

Author

Boldinova, Elizaveta O. ; Khairullin, Rafil F. ; Makarova, Alena V. et al. / Isoforms of base excision repair enzymes produced by alternative splicing. In: International Journal of Molecular Sciences. 2019 ; Vol. 20, No. 13.

BibTeX

@article{5ea628266ea54db7ac836d044d2e59ad,

title = "Isoforms of base excision repair enzymes produced by alternative splicing",

abstract = "Transcripts of many enzymes involved in base excision repair (BER) undergo extensive alternative splicing, but functions of the corresponding alternative splice variants remain largely unexplored. In this review, we cover the studies describing the common alternatively spliced isoforms and disease-associated variants of DNA glycosylases, AP-endonuclease 1, and DNA polymerase beta. We also discuss the roles of alternative splicing in the regulation of their expression, catalytic activities, and intracellular transport.",

keywords = "Alternative splicing, Apurinic/apyrimidinic endonuclease, DNA glycosylases, DNA polymerase beta, apurinic, alternative splicing, DNA-POLYMERASE-BETA, APURINIC APYRIMIDINIC ENDONUCLEASE, DIFFERENTIAL INTRACELLULAR-LOCALIZATION, apyrimidinic endonuclease, DEOXYRIBOSE PHOSPHATE LYASE, MESSENGER-RNA, GLYCOSYLASE DOMAIN, MOLECULAR-CLONING, HUMAN URACIL, MUTY HOMOLOG HMYH, LONG-PATCH REPAIR",

author = "Boldinova, {Elizaveta O.} and Khairullin, {Rafil F.} and Makarova, {Alena V.} and Zharkov, {Dmitry O.}",

note = "Publisher Copyright: {\textcopyright} 2019 by the authors. Licensee MDPI, Basel, Switzerland. T.",

year = "2019",

month = jul,

day = "3",

doi = "10.3390/ijms20133279",

language = "English",

volume = "20",

journal = "International Journal of Molecular Sciences",

issn = "1661-6596",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "13",

}

RIS

TY - JOUR

T1 - Isoforms of base excision repair enzymes produced by alternative splicing

AU - Boldinova, Elizaveta O.

AU - Khairullin, Rafil F.

AU - Makarova, Alena V.

AU - Zharkov, Dmitry O.

PY - 2019/7/3

Y1 - 2019/7/3

N2 - Transcripts of many enzymes involved in base excision repair (BER) undergo extensive alternative splicing, but functions of the corresponding alternative splice variants remain largely unexplored. In this review, we cover the studies describing the common alternatively spliced isoforms and disease-associated variants of DNA glycosylases, AP-endonuclease 1, and DNA polymerase beta. We also discuss the roles of alternative splicing in the regulation of their expression, catalytic activities, and intracellular transport.

AB - Transcripts of many enzymes involved in base excision repair (BER) undergo extensive alternative splicing, but functions of the corresponding alternative splice variants remain largely unexplored. In this review, we cover the studies describing the common alternatively spliced isoforms and disease-associated variants of DNA glycosylases, AP-endonuclease 1, and DNA polymerase beta. We also discuss the roles of alternative splicing in the regulation of their expression, catalytic activities, and intracellular transport.

KW - Alternative splicing

KW - Apurinic/apyrimidinic endonuclease

KW - DNA glycosylases

KW - DNA polymerase beta

KW - apurinic

KW - alternative splicing

KW - DNA-POLYMERASE-BETA

KW - APURINIC APYRIMIDINIC ENDONUCLEASE

KW - DIFFERENTIAL INTRACELLULAR-LOCALIZATION

KW - apyrimidinic endonuclease

KW - DEOXYRIBOSE PHOSPHATE LYASE

KW - MESSENGER-RNA

KW - GLYCOSYLASE DOMAIN

KW - MOLECULAR-CLONING

KW - HUMAN URACIL

KW - MUTY HOMOLOG HMYH

KW - LONG-PATCH REPAIR

UR - http://www.scopus.com/inward/record.url?scp=85068681481&partnerID=8YFLogxK

U2 - 10.3390/ijms20133279

DO - 10.3390/ijms20133279

M3 - Review article

C2 - 31277343

AN - SCOPUS:85068681481

VL - 20

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

SN - 1661-6596

IS - 13

M1 - 3279

ER -

ID: 20850419