Inhibitors of nuclease and redox activity of apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1)

Original language	English
Pages (from-to)	2531-2544
Number of pages	14
Journal	Bioorganic and Medicinal Chemistry
Volume	25
Issue number	9
DOIs	https://doi.org/10.1016/j.bmc.2017.01.028
Publication status	Published - 1 May 2017

Apurinic/apyrimidinic (AP) site, Apurinic/apyrimidinic endonuclease 1/redox effector factor 1 (APE1/Ref-1), Base excision repair (BER), DNA repair, E3330, Inhibitors, Lucanthone, Methoxyamine, BASE-EXCISION-REPAIR, APURINIC-APYRIMIDINIC ENDONUCLEASE, FACTOR-I, SIGNALING PROTEIN APE1/REF-1, ABASIC ENDONUCLEASE, SMALL-MOLECULE INHIBITOR, DNA-BINDING ACTIVITY, CELL LUNG-CANCER, HUMAN AP ENDONUCLEASE-1, NF-KAPPA-B, Humans, DNA Repair/drug effects, Enzyme Inhibitors/chemistry, Oxidation-Reduction, Neoplasms/drug therapy, DNA-(Apurinic or Apyrimidinic Site) Lyase/antagonists & inhibitors, Antineoplastic Agents/chemistry, Animals, Cell Line, Tumor

ID: 8681089