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Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. / Abramova, T. O.; Ryazanova, M. A.; Antonov, E. V. et al.

In: Molekuliarnaia biologiia, Vol. 51, No. 3, 01.05.2017, p. 442-446.

Research output: Contribution to journal › Article › peer-review

Harvard

Abramova, TO, Ryazanova, MA, Antonov, EV, Redina, OE & Markel, AL 2017, 'Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension', Molekuliarnaia biologiia, vol. 51, no. 3, pp. 442-446. https://doi.org/10.7868/S0026898417020021

APA

Abramova, T. O., Ryazanova, M. A., Antonov, E. V., Redina, O. E., & Markel, A. L. (2017). Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. Molekuliarnaia biologiia, 51(3), 442-446. https://doi.org/10.7868/S0026898417020021

Vancouver

Abramova TO, Ryazanova MA, Antonov EV, Redina OE, Markel AL. Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. Molekuliarnaia biologiia. 2017 May 1;51(3):442-446. doi: 10.7868/S0026898417020021

Author

Abramova, T. O. ; Ryazanova, M. A. ; Antonov, E. V. et al. / Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension. In: Molekuliarnaia biologiia. 2017 ; Vol. 51, No. 3. pp. 442-446.

BibTeX

@article{65c6b384d0a2428eb76d17e29c7034cf,
title = "Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension",
abstract = "The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.",
keywords = "arterial hypertension, ELISA, ISIAH rat strain, real time PCR, renal medulla, soluble epoxide hydrolase, Animals, Blood Pressure, Disease Models, Animal, Epoxide Hydrolases/biosynthesis, Humans, Hypertension/enzymology, Kidney Medulla/enzymology, Male, Nitric Oxide Synthase/genetics, Nitrogen Oxides/metabolism, Oxidative Stress/genetics, Rats, Stress, Physiological/genetics",
author = "Abramova, {T. O.} and Ryazanova, {M. A.} and Antonov, {E. V.} and Redina, {O. E.} and Markel, {A. L.}",
year = "2017",
month = may,
day = "1",
doi = "10.7868/S0026898417020021",
language = "English",
volume = "51",
pages = "442--446",
journal = "Molekulyarnaya Biologiya",
issn = "0026-8984",
publisher = "Russian Academy of Sciences",
number = "3",

}

RIS

TY - JOUR

T1 - Increase in the concentration of sEH protein in renal medulla of ISIAH rats with inherited stress-induced arterial hypertension

AU - Abramova, T. O.

AU - Ryazanova, M. A.

AU - Antonov, E. V.

AU - Redina, O. E.

AU - Markel, A. L.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.

AB - The concentration of soluble epoxide hydrolase (sEH) protein was studied in renal medulla of adult rats from hypertensive ISIAH strain and normotensive WAG strain. The sEH is a key enzyme in metabolism of epoxyeicosatrienoic acids capable of activating endothelial NO-synthase and nitrogen oxide formation, and therefore being vasodilators. An increase in the sEH protein concentration (that we found) allows one to assume that the oxidative stress is increased in the renal medulla of hypertensive rats, and the bloodflow is decreased.

KW - arterial hypertension

KW - ELISA

KW - ISIAH rat strain

KW - real time PCR

KW - renal medulla

KW - soluble epoxide hydrolase

KW - Animals

KW - Blood Pressure

KW - Disease Models, Animal

KW - Epoxide Hydrolases/biosynthesis

KW - Humans

KW - Hypertension/enzymology

KW - Kidney Medulla/enzymology

KW - Male

KW - Nitric Oxide Synthase/genetics

KW - Nitrogen Oxides/metabolism

KW - Oxidative Stress/genetics

KW - Rats

KW - Stress, Physiological/genetics

UR - http://www.scopus.com/inward/record.url?scp=85032638711&partnerID=8YFLogxK

U2 - 10.7868/S0026898417020021

DO - 10.7868/S0026898417020021

M3 - Article

C2 - 28707660

AN - SCOPUS:85032638711

VL - 51

SP - 442

EP - 446

JO - Molekulyarnaya Biologiya

JF - Molekulyarnaya Biologiya

SN - 0026-8984

IS - 3

ER -

ID: 8674971