Research output: Contribution to journal › Article › peer-review
In vitro photodynamic inactivation of Mycobacterium tuberculosis by methylene blue. / Bredikhin, D.; Nikonov, S. D.; Cherednichenko, A. G. et al.
In: Tuberculosis and Lung Diseases, Vol. 97, No. 7, 01.01.2019, p. 28-33.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - In vitro photodynamic inactivation of Mycobacterium tuberculosis by methylene blue
AU - Bredikhin, D.
AU - Nikonov, S. D.
AU - Cherednichenko, A. G.
AU - Petrenko, T. I.
AU - Korbut, A. I.
N1 - Бредихин Д.А., Никонов С.Д., Чередниченко А.Г., Петренко Т.И., Корбут А.И. Фотодинамическая инактивация Mycobacterium tuberculosis метиленовым синим in vitro // Туберкулез и болезни легких. - 2019. - Т. 97. - № 7. - С. 28-33
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The objective: to investigate the anti-tuberculosis effect of laser photodynamic inactivation (PDI) of M. tuberculosis H37Rv in vitro by methylene blue (MB) in the minimum concentration (1 μg/ml) with laser radiation of 662 nm. Subjects and methods. A comparative analysis of the intensity of growth of Mycobacterium tuberculosis H37Rv after laser irradiation and laser FDI by MB with different doses of light energy was carried out. Results. Laser radiation with a wavelength of 662 nm was found to have an inhibitory effect on the growth of M. tuberculosis H37Rv. FDI of Mycobacterium tuberculosis was first registered in the presence of a minimum concentration of MB (1 µg/ml) which suppressed colony growth by 97 and 93% when they were processed by radiation with a wavelength of 662 nm with the lowest density of doses of light energy (46.9 and 93.75 J/cm2).
AB - The objective: to investigate the anti-tuberculosis effect of laser photodynamic inactivation (PDI) of M. tuberculosis H37Rv in vitro by methylene blue (MB) in the minimum concentration (1 μg/ml) with laser radiation of 662 nm. Subjects and methods. A comparative analysis of the intensity of growth of Mycobacterium tuberculosis H37Rv after laser irradiation and laser FDI by MB with different doses of light energy was carried out. Results. Laser radiation with a wavelength of 662 nm was found to have an inhibitory effect on the growth of M. tuberculosis H37Rv. FDI of Mycobacterium tuberculosis was first registered in the presence of a minimum concentration of MB (1 µg/ml) which suppressed colony growth by 97 and 93% when they were processed by radiation with a wavelength of 662 nm with the lowest density of doses of light energy (46.9 and 93.75 J/cm2).
KW - Anti-microbial photodynamic therapy
KW - Methylene blue
KW - Mycobacterium tuberculosis HRv
KW - Tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=85071657621&partnerID=8YFLogxK
UR - https://elibrary.ru/item.asp?id=39147991
U2 - 10.21292/2075-1230-2019-97-7-28-33
DO - 10.21292/2075-1230-2019-97-7-28-33
M3 - Article
AN - SCOPUS:85071657621
VL - 97
SP - 28
EP - 33
JO - Tuberculosis and Lung Diseases
JF - Tuberculosis and Lung Diseases
SN - 2075-1230
IS - 7
ER -
ID: 21443607