Improving Stability and Specificity of CRISPR/Cas9 System by Selective Modification of Guide RNAs with 2'-fluoro and Locked Nucleic Acid Nucleotides

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	13460
Journal	International Journal of Molecular Sciences
Volume	23
Issue number	21
DOIs	https://doi.org/10.3390/ijms232113460
Publication status	Published - 3 Nov 2022

2’-fluoro RNA, 2’-modification, 2’-O-methyl RNA, CRISPR, crRNA, gene editing, LNA, off-target effect, sgRNA, tracrRNA

ID: 39330720