Research output: Contribution to journal › Article › peer-review
Hypothetical Mechanism of Skin Argyria. / Burmistrov, Vasily; Burmistrov, Alexander; Odegova, Galina et al.
In: Coatings, Vol. 12, No. 4, 532, 04.2022.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Hypothetical Mechanism of Skin Argyria
AU - Burmistrov, Vasily
AU - Burmistrov, Alexander
AU - Odegova, Galina
AU - Pestryakov, Alexey
AU - Luna-Vázquez-gómez, Roberto
AU - Bogdanchikova, Nina
N1 - Funding Information: The authors acknowledge Tomsk Polytechnic University Development Program Priority 2030. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/4
Y1 - 2022/4
N2 - Introduction. Argyria is an acquired skin condition that appears after the exposure or consumption of silver, leading to blue or grey coloration of the skin and mucosa. The aim of the present work was to draw researchers’ attention to two aspects of the argyria that until now have not received enough consideration. They are: (1) the process of delivering silver compound from the gastrointestinal tract to the skin and (2) the possibility for silver chloride to participate in this process along with the silver proteinates. Methodology. Illustrative experiments included the observation of color change (visual and using UV-Vis spectrometry) under different light exposure conditions of silver chloride sol in a sweat-simulating solution, in vials and under pig skin (in direct contact). Results and Discussion. A hypothetical mechanism based on a perspiration system for delivering the silver compounds from the gastrointestinal tract to the skin for argyria was proposed. It was also proposed not to completely exclude the partial participation of silver chloride along with the silver proteinates in this process.
AB - Introduction. Argyria is an acquired skin condition that appears after the exposure or consumption of silver, leading to blue or grey coloration of the skin and mucosa. The aim of the present work was to draw researchers’ attention to two aspects of the argyria that until now have not received enough consideration. They are: (1) the process of delivering silver compound from the gastrointestinal tract to the skin and (2) the possibility for silver chloride to participate in this process along with the silver proteinates. Methodology. Illustrative experiments included the observation of color change (visual and using UV-Vis spectrometry) under different light exposure conditions of silver chloride sol in a sweat-simulating solution, in vials and under pig skin (in direct contact). Results and Discussion. A hypothetical mechanism based on a perspiration system for delivering the silver compounds from the gastrointestinal tract to the skin for argyria was proposed. It was also proposed not to completely exclude the partial participation of silver chloride along with the silver proteinates in this process.
KW - argyrosis
KW - hypothetical mechanism
KW - perspiration system
KW - silver skin pigmentation
KW - skin argyria
UR - http://www.scopus.com/inward/record.url?scp=85129041564&partnerID=8YFLogxK
U2 - 10.3390/coatings12040532
DO - 10.3390/coatings12040532
M3 - Article
AN - SCOPUS:85129041564
VL - 12
JO - Coatings
JF - Coatings
SN - 2079-6412
IS - 4
M1 - 532
ER -
ID: 36048147