Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
HBsAg Prevalence among Conditionally Healthy Population of Russia in 1982–2023: An Attempt to Systematic Review and Forecasting the Trend. / Мануйлов, Виктор Александрович; Нетёсов, Сергей Викторович.
Hepatitis - Recent Advances in 2025. ed. / Xingshun Qi; Chengwei Tang. 2025.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review
}
TY - CHAP
T1 - HBsAg Prevalence among Conditionally Healthy Population of Russia in 1982–2023: An Attempt to Systematic Review and Forecasting the Trend
AU - Мануйлов, Виктор Александрович
AU - Нетёсов, Сергей Викторович
N1 - This study was funded by the state assignment for research at Novosibirsk State University, project No. FSUS-2020-0035.
PY - 2025/11/19
Y1 - 2025/11/19
N2 - Data on the dynamics of HBsAg carriers as well as acute and chronic hepatitis Bcases in Russia over the past 30 years were collected. An analysis of the quality of these data is presented, revealing methodology issues in recruiting and screening volunteers. Possible mistakes in analyzing these data are discussed. Analysis of published data in 58 groups of conditionally healthy individuals in Russia showed a rapid decrease in HBsAg prevalence, following the dynamics of hepatitis B incidence. In the 1990s, HBsAg prevalence ranged from 2 to 5% to 10–17% (in different regions), and by 2020, this parameter had decreased to levels from 0.2–0.8% to 2–4%. The incidence of acute hepatitis B during this period decreased from 42 to 0.3 new cases per 100 k/year, while chronic hepatitis B cases decreased from 100 to 20 per 100 k/year. Further measures to propose hepatitis B virus (HBV) eradication are discussed, along with current problems related to declining vaccination.
AB - Data on the dynamics of HBsAg carriers as well as acute and chronic hepatitis Bcases in Russia over the past 30 years were collected. An analysis of the quality of these data is presented, revealing methodology issues in recruiting and screening volunteers. Possible mistakes in analyzing these data are discussed. Analysis of published data in 58 groups of conditionally healthy individuals in Russia showed a rapid decrease in HBsAg prevalence, following the dynamics of hepatitis B incidence. In the 1990s, HBsAg prevalence ranged from 2 to 5% to 10–17% (in different regions), and by 2020, this parameter had decreased to levels from 0.2–0.8% to 2–4%. The incidence of acute hepatitis B during this period decreased from 42 to 0.3 new cases per 100 k/year, while chronic hepatitis B cases decreased from 100 to 20 per 100 k/year. Further measures to propose hepatitis B virus (HBV) eradication are discussed, along with current problems related to declining vaccination.
KW - viral hepatitis
KW - hepatitis B virus
KW - prevalence
KW - chronic HBV carriers
KW - HBsAg
KW - Russian federation
U2 - 10.5772/intechopen.1007787
DO - 10.5772/intechopen.1007787
M3 - Chapter
SN - 978-1-83634-341-7
SN - 978-1-83634-340-0
BT - Hepatitis - Recent Advances in 2025
A2 - Qi, Xingshun
A2 - Tang, Chengwei
ER -
ID: 76587329