Standard

Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus. / Tkachev, S. E.; Babkin, I. V.; Chicherina, G. S. et al.

In: Ticks and Tick-borne Diseases, Vol. 11, No. 2, 101327, 03.2020.

Research output: Contribution to journal › Article › peer-review

Harvard

Tkachev, SE, Babkin, IV, Chicherina, GS, Kozlova, IV, Verkhozina, MM, Demina, TV, Lisak, OV, Doroshchenko, EK, Dzhioev, YP, Suntsova, OV, Belokopytova, PS, Tikunov, AY, Savinova, YS, Paramonov, AI, Glupov, VV, Zlobin, VI & Tikunova, NV 2020, 'Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus', Ticks and Tick-borne Diseases, vol. 11, no. 2, 101327. https://doi.org/10.1016/j.ttbdis.2019.101327

APA

Tkachev, S. E., Babkin, I. V., Chicherina, G. S., Kozlova, I. V., Verkhozina, M. M., Demina, T. V., Lisak, O. V., Doroshchenko, E. K., Dzhioev, Y. P., Suntsova, O. V., Belokopytova, P. S., Tikunov, A. Y., Savinova, Y. S., Paramonov, A. I., Glupov, V. V., Zlobin, V. I., & Tikunova, N. V. (2020). Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus. Ticks and Tick-borne Diseases, 11(2), [101327]. https://doi.org/10.1016/j.ttbdis.2019.101327

Vancouver

Tkachev SE, Babkin IV, Chicherina GS, Kozlova IV, Verkhozina MM, Demina TV et al. Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus. Ticks and Tick-borne Diseases. 2020 Mar;11(2):101327. doi: 10.1016/j.ttbdis.2019.101327

Author

Tkachev, S. E. ; Babkin, I. V. ; Chicherina, G. S. et al. / Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus. In: Ticks and Tick-borne Diseases. 2020 ; Vol. 11, No. 2.

BibTeX

@article{22fd67b7a8014ebf9b32286b92da7068,
title = "Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus",
abstract = "The tick-borne encephalitis virus (TBEV), a member of the Flaviviridae family, is currently subdivided into three main subtypes—the European (TBEV-Eu), the Far-Eastern (TBEV-FE), and the Siberian (TBEV-Sib). The TBEV-Sib is the most common subtype and found in all regions where TBEV was detected, except for Central and Western Europe. Currently, four genetic lineages have been described within TBEV-Sib. In this study, detailed analysis of TBEV-Sib genetic diversity, geographic distribution, phylogeography and divergence time of different TBEV-Sib genetic lineages based on E gene fragments, complete genome sequences, and all currently available data in the GenBank database was performed. As a result, a novel Bosnia lineage within the TBEV-Sib was identified. It was demonstrated that the Zausaev lineage is the most widely distributed among the TBEV-Sib lineages, and was detected in all studied regions except the Far East. The Vasilchenko lineage was found from Western Siberia to the Far East. The Baltic lineage is presented from Europe to Western Siberia. The Obskaya lineage was found only in Western Siberia. TBEV strains from a newly described Bosnia lineage were detected in Bosnia, the Crimean peninsula, Kyrgyzstan and Kazakhstan. The greatest divergence of the TBEV-Sib genetic variants was observed in Western Siberia. Within the TBEV-Sib, the Obskaya lineage diverged from the common ancestor the earliest, after that the Bosnia lineage was separated, then the Baltic lineage, and the Zausaev and Vasilchenko lineages diverged most recently.",
keywords = "Genetic diversity, Genetic lineages, Phylogeography, Siberian subtype, Tick-borne encephalitis virus",
author = "Tkachev, {S. E.} and Babkin, {I. V.} and Chicherina, {G. S.} and Kozlova, {I. V.} and Verkhozina, {M. M.} and Demina, {T. V.} and Lisak, {O. V.} and Doroshchenko, {E. K.} and Dzhioev, {Yu P.} and Suntsova, {O. V.} and Belokopytova, {P. S.} and Tikunov, {A. Yu} and Savinova, {Yu S.} and Paramonov, {A. I.} and Glupov, {V. V.} and Zlobin, {V. I.} and Tikunova, {N. V.}",
note = "Funding Information: This study was carried out with the partial financial support of the Russian State funded budget project #АААА-А17-117020210027-9, research work № 01201282421 (0542-2014-0006), and RFBR and the Government of the Novosibirsk region research project № 18-44-540021. Appendix A Publisher Copyright: {\textcopyright} 2019 Elsevier GmbH",
year = "2020",
month = mar,
doi = "10.1016/j.ttbdis.2019.101327",
language = "English",
volume = "11",
journal = "Ticks and Tick-borne Diseases",
issn = "1877-959X",
publisher = "Elsevier GmbH",
number = "2",

}

RIS

TY - JOUR

T1 - Genetic diversity and geographical distribution of the Siberian subtype of the tick-borne encephalitis virus

AU - Tkachev, S. E.

AU - Babkin, I. V.

AU - Chicherina, G. S.

AU - Kozlova, I. V.

AU - Verkhozina, M. M.

AU - Demina, T. V.

AU - Lisak, O. V.

AU - Doroshchenko, E. K.

AU - Dzhioev, Yu P.

AU - Suntsova, O. V.

AU - Belokopytova, P. S.

AU - Tikunov, A. Yu

AU - Savinova, Yu S.

AU - Paramonov, A. I.

AU - Glupov, V. V.

AU - Zlobin, V. I.

AU - Tikunova, N. V.

N1 - Funding Information: This study was carried out with the partial financial support of the Russian State funded budget project #АААА-А17-117020210027-9, research work № 01201282421 (0542-2014-0006), and RFBR and the Government of the Novosibirsk region research project № 18-44-540021. Appendix A Publisher Copyright: © 2019 Elsevier GmbH

PY - 2020/3

Y1 - 2020/3

N2 - The tick-borne encephalitis virus (TBEV), a member of the Flaviviridae family, is currently subdivided into three main subtypes—the European (TBEV-Eu), the Far-Eastern (TBEV-FE), and the Siberian (TBEV-Sib). The TBEV-Sib is the most common subtype and found in all regions where TBEV was detected, except for Central and Western Europe. Currently, four genetic lineages have been described within TBEV-Sib. In this study, detailed analysis of TBEV-Sib genetic diversity, geographic distribution, phylogeography and divergence time of different TBEV-Sib genetic lineages based on E gene fragments, complete genome sequences, and all currently available data in the GenBank database was performed. As a result, a novel Bosnia lineage within the TBEV-Sib was identified. It was demonstrated that the Zausaev lineage is the most widely distributed among the TBEV-Sib lineages, and was detected in all studied regions except the Far East. The Vasilchenko lineage was found from Western Siberia to the Far East. The Baltic lineage is presented from Europe to Western Siberia. The Obskaya lineage was found only in Western Siberia. TBEV strains from a newly described Bosnia lineage were detected in Bosnia, the Crimean peninsula, Kyrgyzstan and Kazakhstan. The greatest divergence of the TBEV-Sib genetic variants was observed in Western Siberia. Within the TBEV-Sib, the Obskaya lineage diverged from the common ancestor the earliest, after that the Bosnia lineage was separated, then the Baltic lineage, and the Zausaev and Vasilchenko lineages diverged most recently.

AB - The tick-borne encephalitis virus (TBEV), a member of the Flaviviridae family, is currently subdivided into three main subtypes—the European (TBEV-Eu), the Far-Eastern (TBEV-FE), and the Siberian (TBEV-Sib). The TBEV-Sib is the most common subtype and found in all regions where TBEV was detected, except for Central and Western Europe. Currently, four genetic lineages have been described within TBEV-Sib. In this study, detailed analysis of TBEV-Sib genetic diversity, geographic distribution, phylogeography and divergence time of different TBEV-Sib genetic lineages based on E gene fragments, complete genome sequences, and all currently available data in the GenBank database was performed. As a result, a novel Bosnia lineage within the TBEV-Sib was identified. It was demonstrated that the Zausaev lineage is the most widely distributed among the TBEV-Sib lineages, and was detected in all studied regions except the Far East. The Vasilchenko lineage was found from Western Siberia to the Far East. The Baltic lineage is presented from Europe to Western Siberia. The Obskaya lineage was found only in Western Siberia. TBEV strains from a newly described Bosnia lineage were detected in Bosnia, the Crimean peninsula, Kyrgyzstan and Kazakhstan. The greatest divergence of the TBEV-Sib genetic variants was observed in Western Siberia. Within the TBEV-Sib, the Obskaya lineage diverged from the common ancestor the earliest, after that the Bosnia lineage was separated, then the Baltic lineage, and the Zausaev and Vasilchenko lineages diverged most recently.

KW - Genetic diversity

KW - Genetic lineages

KW - Phylogeography

KW - Siberian subtype

KW - Tick-borne encephalitis virus

UR - http://www.scopus.com/inward/record.url?scp=85075909886&partnerID=8YFLogxK

U2 - 10.1016/j.ttbdis.2019.101327

DO - 10.1016/j.ttbdis.2019.101327

M3 - Article

C2 - 31767494

AN - SCOPUS:85075909886

VL - 11

JO - Ticks and Tick-borne Diseases

JF - Ticks and Tick-borne Diseases

SN - 1877-959X

IS - 2

M1 - 101327

ER -

ID: 27698826