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Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. / Tambets, Kristiina; Yunusbayev, Bayazit; Hudjashov, Georgi et al.

In: Genome Biology, Vol. 19, No. 1, 139, 21.09.2018, p. 139.

Research output: Contribution to journalArticlepeer-review

Harvard

Tambets, K, Yunusbayev, B, Hudjashov, G, Ilumäe, AM, Rootsi, S, Honkola, T, Vesakoski, O, Atkinson, Q, Skoglund, P, Kushniarevich, A, Litvinov, S, Reidla, M, Metspalu, E, Saag, L, Rantanen, T, Karmin, M, Parik, J, Zhadanov, SI, Gubina, M, Damba, LD, Bermisheva, M, Reisberg, T, Dibirova, K, Evseeva, I, Nelis, M, Klovins, J, Metspalu, A, Esko, T, Balanovsky, O, Balanovska, E, Khusnutdinova, EK, Osipova, LP, Voevoda, M, Villems, R, Kivisild, T & Metspalu, M 2018, 'Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations', Genome Biology, vol. 19, no. 1, 139, pp. 139. https://doi.org/10.1186/s13059-018-1522-1

APA

Tambets, K., Yunusbayev, B., Hudjashov, G., Ilumäe, A. M., Rootsi, S., Honkola, T., Vesakoski, O., Atkinson, Q., Skoglund, P., Kushniarevich, A., Litvinov, S., Reidla, M., Metspalu, E., Saag, L., Rantanen, T., Karmin, M., Parik, J., Zhadanov, S. I., Gubina, M., ... Metspalu, M. (2018). Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. Genome Biology, 19(1), 139. [139]. https://doi.org/10.1186/s13059-018-1522-1

Vancouver

Tambets K, Yunusbayev B, Hudjashov G, Ilumäe AM, Rootsi S, Honkola T et al. Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. Genome Biology. 2018 Sept 21;19(1):139. 139. doi: 10.1186/s13059-018-1522-1

Author

Tambets, Kristiina ; Yunusbayev, Bayazit ; Hudjashov, Georgi et al. / Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations. In: Genome Biology. 2018 ; Vol. 19, No. 1. pp. 139.

BibTeX

@article{7bc02bd8677c4f729055791a22d61cd5,
title = "Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations",
abstract = "Background: The genetic origins of Uralic speakers from across a vast territory in the temperate zone of North Eurasia have remained elusive. Previous studies have shown contrasting proportions of Eastern and Western Eurasian ancestry in their mitochondrial and Y chromosomal gene pools. While the maternal lineages reflect by and large the geographic background of a given Uralic-speaking population, the frequency of Y chromosomes of Eastern Eurasian origin is distinctively high among European Uralic speakers. The autosomal variation of Uralic speakers, however, has not yet been studied comprehensively. Results: Here, we present a genome-wide analysis of 15 Uralic-speaking populations which cover all main groups of the linguistic family. We show that contemporary Uralic speakers are genetically very similar to their local geographical neighbours. However, when studying relationships among geographically distant populations, we find that most of the Uralic speakers and some of their neighbours share a genetic component of possibly Siberian origin. Additionally, we show that most Uralic speakers share significantly more genomic segments identity-by-descent with each other than with geographically equidistant speakers of other languages. We find that correlated genome-wide genetic and lexical distances among Uralic speakers suggest co-dispersion of genes and languages. Yet, we do not find long-range genetic ties between Estonians and Hungarians with their linguistic sisters that would distinguish them from their non-Uralic-speaking neighbours. Conclusions: We show that most Uralic speakers share a distinct ancestry component of likely Siberian origin, which suggests that the spread of Uralic languages involved at least some demic component.",
keywords = "Genome-wide analysis, Haplotype analysis, IBD-segments, Population genetics, Uralic languages, European Continental Ancestry Group/genetics, Demography, Genes, Humans, Genetic Variation, Asian Continental Ancestry Group/genetics, Linguistics, Genome, Human, Population Dynamics, REGRESSION, WEST, PATTERNS, ADMIXTURE, INFERENCE, MITOCHONDRIAL-DNA, ANCESTRY, CHROMOSOME HAPLOGROUP-N, DIVERSITY, SELECTION",
author = "Kristiina Tambets and Bayazit Yunusbayev and Georgi Hudjashov and Ilum{\"a}e, {Anne Mai} and Siiri Rootsi and Terhi Honkola and Outi Vesakoski and Quentin Atkinson and Pontus Skoglund and Alena Kushniarevich and Sergey Litvinov and Maere Reidla and Ene Metspalu and Lehti Saag and Timo Rantanen and Monika Karmin and J{\"u}ri Parik and Zhadanov, {Sergey I.} and Marina Gubina and Damba, {Larisa D.} and Marina Bermisheva and Tuuli Reisberg and Khadizhat Dibirova and Irina Evseeva and Mari Nelis and Janis Klovins and Andres Metspalu and T{\~o}nu Esko and Oleg Balanovsky and Elena Balanovska and Khusnutdinova, {Elza K.} and Osipova, {Ludmila P.} and Mikhail Voevoda and Richard Villems and Toomas Kivisild and Mait Metspalu",
note = "Publisher Copyright: {\textcopyright} 2018 The Author(s).",
year = "2018",
month = sep,
day = "21",
doi = "10.1186/s13059-018-1522-1",
language = "English",
volume = "19",
pages = "139",
journal = "Genome Biology",
issn = "1474-7596",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Genes reveal traces of common recent demographic history for most of the Uralic-speaking populations

AU - Tambets, Kristiina

AU - Yunusbayev, Bayazit

AU - Hudjashov, Georgi

AU - Ilumäe, Anne Mai

AU - Rootsi, Siiri

AU - Honkola, Terhi

AU - Vesakoski, Outi

AU - Atkinson, Quentin

AU - Skoglund, Pontus

AU - Kushniarevich, Alena

AU - Litvinov, Sergey

AU - Reidla, Maere

AU - Metspalu, Ene

AU - Saag, Lehti

AU - Rantanen, Timo

AU - Karmin, Monika

AU - Parik, Jüri

AU - Zhadanov, Sergey I.

AU - Gubina, Marina

AU - Damba, Larisa D.

AU - Bermisheva, Marina

AU - Reisberg, Tuuli

AU - Dibirova, Khadizhat

AU - Evseeva, Irina

AU - Nelis, Mari

AU - Klovins, Janis

AU - Metspalu, Andres

AU - Esko, Tõnu

AU - Balanovsky, Oleg

AU - Balanovska, Elena

AU - Khusnutdinova, Elza K.

AU - Osipova, Ludmila P.

AU - Voevoda, Mikhail

AU - Villems, Richard

AU - Kivisild, Toomas

AU - Metspalu, Mait

N1 - Publisher Copyright: © 2018 The Author(s).

PY - 2018/9/21

Y1 - 2018/9/21

N2 - Background: The genetic origins of Uralic speakers from across a vast territory in the temperate zone of North Eurasia have remained elusive. Previous studies have shown contrasting proportions of Eastern and Western Eurasian ancestry in their mitochondrial and Y chromosomal gene pools. While the maternal lineages reflect by and large the geographic background of a given Uralic-speaking population, the frequency of Y chromosomes of Eastern Eurasian origin is distinctively high among European Uralic speakers. The autosomal variation of Uralic speakers, however, has not yet been studied comprehensively. Results: Here, we present a genome-wide analysis of 15 Uralic-speaking populations which cover all main groups of the linguistic family. We show that contemporary Uralic speakers are genetically very similar to their local geographical neighbours. However, when studying relationships among geographically distant populations, we find that most of the Uralic speakers and some of their neighbours share a genetic component of possibly Siberian origin. Additionally, we show that most Uralic speakers share significantly more genomic segments identity-by-descent with each other than with geographically equidistant speakers of other languages. We find that correlated genome-wide genetic and lexical distances among Uralic speakers suggest co-dispersion of genes and languages. Yet, we do not find long-range genetic ties between Estonians and Hungarians with their linguistic sisters that would distinguish them from their non-Uralic-speaking neighbours. Conclusions: We show that most Uralic speakers share a distinct ancestry component of likely Siberian origin, which suggests that the spread of Uralic languages involved at least some demic component.

AB - Background: The genetic origins of Uralic speakers from across a vast territory in the temperate zone of North Eurasia have remained elusive. Previous studies have shown contrasting proportions of Eastern and Western Eurasian ancestry in their mitochondrial and Y chromosomal gene pools. While the maternal lineages reflect by and large the geographic background of a given Uralic-speaking population, the frequency of Y chromosomes of Eastern Eurasian origin is distinctively high among European Uralic speakers. The autosomal variation of Uralic speakers, however, has not yet been studied comprehensively. Results: Here, we present a genome-wide analysis of 15 Uralic-speaking populations which cover all main groups of the linguistic family. We show that contemporary Uralic speakers are genetically very similar to their local geographical neighbours. However, when studying relationships among geographically distant populations, we find that most of the Uralic speakers and some of their neighbours share a genetic component of possibly Siberian origin. Additionally, we show that most Uralic speakers share significantly more genomic segments identity-by-descent with each other than with geographically equidistant speakers of other languages. We find that correlated genome-wide genetic and lexical distances among Uralic speakers suggest co-dispersion of genes and languages. Yet, we do not find long-range genetic ties between Estonians and Hungarians with their linguistic sisters that would distinguish them from their non-Uralic-speaking neighbours. Conclusions: We show that most Uralic speakers share a distinct ancestry component of likely Siberian origin, which suggests that the spread of Uralic languages involved at least some demic component.

KW - Genome-wide analysis

KW - Haplotype analysis

KW - IBD-segments

KW - Population genetics

KW - Uralic languages

KW - European Continental Ancestry Group/genetics

KW - Demography

KW - Genes

KW - Humans

KW - Genetic Variation

KW - Asian Continental Ancestry Group/genetics

KW - Linguistics

KW - Genome, Human

KW - Population Dynamics

KW - REGRESSION

KW - WEST

KW - PATTERNS

KW - ADMIXTURE

KW - INFERENCE

KW - MITOCHONDRIAL-DNA

KW - ANCESTRY

KW - CHROMOSOME HAPLOGROUP-N

KW - DIVERSITY

KW - SELECTION

UR - http://www.scopus.com/inward/record.url?scp=85053601969&partnerID=8YFLogxK

U2 - 10.1186/s13059-018-1522-1

DO - 10.1186/s13059-018-1522-1

M3 - Article

C2 - 30241495

AN - SCOPUS:85053601969

VL - 19

SP - 139

JO - Genome Biology

JF - Genome Biology

SN - 1474-7596

IS - 1

M1 - 139

ER -

ID: 16632522