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Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation. / Grigor'eva, Elena V.; Drozdova, Elena S.; Sorogina, Diana A. et al.

In: Stem Cell Research, Vol. 59, 102651, 03.2022.

Research output: Contribution to journal › Article › peer-review

Harvard

Grigor'eva, EV, Drozdova, ES, Sorogina, DA, Malakhova, AA, Pavlova, SV, Vyatkin, YV, Khabarova, EA, Rzaev, JA, Medvedev, SP & Zakian, SM 2022, 'Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation', Stem Cell Research, vol. 59, 102651. https://doi.org/10.1016/j.scr.2021.102651

APA

Grigor'eva, E. V., Drozdova, E. S., Sorogina, D. A., Malakhova, A. A., Pavlova, S. V., Vyatkin, Y. V., Khabarova, E. A., Rzaev, J. A., Medvedev, S. P., & Zakian, S. M. (2022). Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation. Stem Cell Research, 59, [102651]. https://doi.org/10.1016/j.scr.2021.102651

Vancouver

Grigor'eva EV, Drozdova ES, Sorogina DA, Malakhova AA, Pavlova SV, Vyatkin YV et al. Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation. Stem Cell Research. 2022 Mar;59:102651. Epub 2021 Dec 31. doi: 10.1016/j.scr.2021.102651

Author

Grigor'eva, Elena V. ; Drozdova, Elena S. ; Sorogina, Diana A. et al. / Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation. In: Stem Cell Research. 2022 ; Vol. 59.

BibTeX

@article{e2b3bb6e4f8f4994bdbda9ead28c9641,
title = "Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation",
abstract = "Mutation in the glucocerebrosidase encoding gene (GBA) is one of the most frequent genetic cause of Parkinson's disease. ICGi034-A induced pluripotent stem cell (iPSC) line obtained by reprogramming peripheral blood mononuclear cells (PBMCs) of a patient with heterozygous c.1226A > G (p.N370S) mutation in the GBA gene can be used for studying the fundamental mechanisms of the pathogenesis of GBA-associated Parkinson's disease, and for potential drug screening. The iPSCs express pluripotency markers (NANOG, SSEA4, TRA-1-60, OCT4, SOX2), have a normal karyotype, and are capable of producing derivatives of three germ layers.",
author = "Grigor'eva, {Elena V.} and Drozdova, {Elena S.} and Sorogina, {Diana A.} and Malakhova, {Anastasia A.} and Pavlova, {Sofia V.} and Vyatkin, {Yuri V.} and Khabarova, {Elena A.} and Rzaev, {Jamil A.} and Medvedev, {Sergey P.} and Zakian, {Suren M.}",
note = "Funding Information: This study was supported by the Russian Science Foundation , grant № 19-75-20063 . FSBI Federal Neurosurgical Center provided PBMCs of Parkinson{\textquoteright}s disease patient. Clinical exome sequencing was analysed in Novosibirsk State University. The mouse embryonic fibroblasts were obtained at the Common Facilities Centre “SPF-vivarium of the ICG SB RAS” (https://ckp.icgen.ru/spf/). The immunofluorescent imaging was performed using resources of the Common Facilities Center of Microscopic Analysis of Biological Objects, ICG SB RAS (https://ckp.icgen.ru/ckpmabo/), supported by the State project of the Institute of Cytology and Genetics (# 0259-2021-0011). Publisher Copyright: {\textcopyright} 2022 The Authors",
year = "2022",
month = mar,
doi = "10.1016/j.scr.2021.102651",
language = "English",
volume = "59",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Generation of induced pluripotent stem cell line, ICGi034-A, by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease associated with GBA mutation

AU - Grigor'eva, Elena V.

AU - Drozdova, Elena S.

AU - Sorogina, Diana A.

AU - Malakhova, Anastasia A.

AU - Pavlova, Sofia V.

AU - Vyatkin, Yuri V.

AU - Khabarova, Elena A.

AU - Rzaev, Jamil A.

AU - Medvedev, Sergey P.

AU - Zakian, Suren M.

N1 - Funding Information: This study was supported by the Russian Science Foundation , grant № 19-75-20063 . FSBI Federal Neurosurgical Center provided PBMCs of Parkinson’s disease patient. Clinical exome sequencing was analysed in Novosibirsk State University. The mouse embryonic fibroblasts were obtained at the Common Facilities Centre “SPF-vivarium of the ICG SB RAS” (https://ckp.icgen.ru/spf/). The immunofluorescent imaging was performed using resources of the Common Facilities Center of Microscopic Analysis of Biological Objects, ICG SB RAS (https://ckp.icgen.ru/ckpmabo/), supported by the State project of the Institute of Cytology and Genetics (# 0259-2021-0011). Publisher Copyright: © 2022 The Authors

PY - 2022/3

Y1 - 2022/3

N2 - Mutation in the glucocerebrosidase encoding gene (GBA) is one of the most frequent genetic cause of Parkinson's disease. ICGi034-A induced pluripotent stem cell (iPSC) line obtained by reprogramming peripheral blood mononuclear cells (PBMCs) of a patient with heterozygous c.1226A > G (p.N370S) mutation in the GBA gene can be used for studying the fundamental mechanisms of the pathogenesis of GBA-associated Parkinson's disease, and for potential drug screening. The iPSCs express pluripotency markers (NANOG, SSEA4, TRA-1-60, OCT4, SOX2), have a normal karyotype, and are capable of producing derivatives of three germ layers.

AB - Mutation in the glucocerebrosidase encoding gene (GBA) is one of the most frequent genetic cause of Parkinson's disease. ICGi034-A induced pluripotent stem cell (iPSC) line obtained by reprogramming peripheral blood mononuclear cells (PBMCs) of a patient with heterozygous c.1226A > G (p.N370S) mutation in the GBA gene can be used for studying the fundamental mechanisms of the pathogenesis of GBA-associated Parkinson's disease, and for potential drug screening. The iPSCs express pluripotency markers (NANOG, SSEA4, TRA-1-60, OCT4, SOX2), have a normal karyotype, and are capable of producing derivatives of three germ layers.

UR - http://www.scopus.com/inward/record.url?scp=85122427805&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2021.102651

DO - 10.1016/j.scr.2021.102651

M3 - Article

C2 - 35007918

AN - SCOPUS:85122427805

VL - 59

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

M1 - 102651

ER -

ID: 35197808