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Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress. / Idova, G. V.; Cheido, M. A.; Zhukova, E. N. et al.

In: Neuroscience and Behavioral Physiology, Vol. 48, No. 4, 01.05.2018, p. 506-510.

Research output: Contribution to journal › Article › peer-review

Harvard

Idova, GV, Cheido, MA, Zhukova, EN & Al’perina, EL 2018, 'Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress', Neuroscience and Behavioral Physiology, vol. 48, no. 4, pp. 506-510. https://doi.org/10.1007/s11055-018-0592-6

APA

Idova, G. V., Cheido, M. A., Zhukova, E. N., & Al’perina, E. L. (2018). Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress. Neuroscience and Behavioral Physiology, 48(4), 506-510. https://doi.org/10.1007/s11055-018-0592-6

Vancouver

Idova GV, Cheido MA, Zhukova EN, Al’perina EL. Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress. Neuroscience and Behavioral Physiology. 2018 May 1;48(4):506-510. doi: 10.1007/s11055-018-0592-6

Author

Idova, G. V. ; Cheido, M. A. ; Zhukova, E. N. et al. / Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress. In: Neuroscience and Behavioral Physiology. 2018 ; Vol. 48, No. 4. pp. 506-510.

BibTeX

@article{92177fc1388f4b8f911698c54cdf3437,
title = "Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress",
abstract = "Chronic (10 days)administration of the atypical antipsychotic quetiapine (3.75 mg/kg) induced significant suppression of the IgM immune response in mice with aggressive behavior formed as a result of prolonged (14 days in CBA mice, 20 days in C57BL/6J mice) confrontations and in animals with unaltered psychoemotional status. The immunosuppressive action of quetiapine was independent of the genotype of the mice and the route (i.p. or p.o.) and scheme (single or repeated) of administration. Possible serotonin (5-HT) and dopamine (DA) receptor mechanisms of the immunomodulatory effects of quetiapine are discussed.",
keywords = "5-HT receptors, aggressive behavior, IgM immune response, quetiapine, social stress",
author = "Idova, {G. V.} and Cheido, {M. A.} and Zhukova, {E. N.} and Al{\textquoteright}perina, {E. L.}",
year = "2018",
month = may,
day = "1",
doi = "10.1007/s11055-018-0592-6",
language = "English",
volume = "48",
pages = "506--510",
journal = "Neuroscience and Behavioral Physiology",
issn = "0097-0549",
publisher = "Springer New York",
number = "4",

}

RIS

TY - JOUR

T1 - Effects of the Atypical Antipsychotic Quetiapine on the Immune Response in Aggressive Mice in a Model of Social Stress

AU - Idova, G. V.

AU - Cheido, M. A.

AU - Zhukova, E. N.

AU - Al’perina, E. L.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Chronic (10 days)administration of the atypical antipsychotic quetiapine (3.75 mg/kg) induced significant suppression of the IgM immune response in mice with aggressive behavior formed as a result of prolonged (14 days in CBA mice, 20 days in C57BL/6J mice) confrontations and in animals with unaltered psychoemotional status. The immunosuppressive action of quetiapine was independent of the genotype of the mice and the route (i.p. or p.o.) and scheme (single or repeated) of administration. Possible serotonin (5-HT) and dopamine (DA) receptor mechanisms of the immunomodulatory effects of quetiapine are discussed.

AB - Chronic (10 days)administration of the atypical antipsychotic quetiapine (3.75 mg/kg) induced significant suppression of the IgM immune response in mice with aggressive behavior formed as a result of prolonged (14 days in CBA mice, 20 days in C57BL/6J mice) confrontations and in animals with unaltered psychoemotional status. The immunosuppressive action of quetiapine was independent of the genotype of the mice and the route (i.p. or p.o.) and scheme (single or repeated) of administration. Possible serotonin (5-HT) and dopamine (DA) receptor mechanisms of the immunomodulatory effects of quetiapine are discussed.

KW - 5-HT receptors

KW - aggressive behavior

KW - IgM immune response

KW - quetiapine

KW - social stress

UR - http://www.scopus.com/inward/record.url?scp=85045906059&partnerID=8YFLogxK

U2 - 10.1007/s11055-018-0592-6

DO - 10.1007/s11055-018-0592-6

M3 - Article

AN - SCOPUS:85045906059

VL - 48

SP - 506

EP - 510

JO - Neuroscience and Behavioral Physiology

JF - Neuroscience and Behavioral Physiology

SN - 0097-0549

IS - 4

ER -

ID: 12819762