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Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats. / Igonina, Tatyana N.; Ragaeva, Diana S.; Petrova, Olga M. et al.

In: Hypertension in pregnancy, Vol. 38, No. 4, 02.10.2019, p. 208-216.

Research output: Contribution to journalArticlepeer-review

Harvard

Igonina, TN, Ragaeva, DS, Petrova, OM, Rozkova, IN, Brusentsev, EY & Amstislavsky, SY 2019, 'Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats', Hypertension in pregnancy, vol. 38, no. 4, pp. 208-216. https://doi.org/10.1080/10641955.2019.1647232

APA

Igonina, T. N., Ragaeva, D. S., Petrova, O. M., Rozkova, I. N., Brusentsev, E. Y., & Amstislavsky, S. Y. (2019). Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats. Hypertension in pregnancy, 38(4), 208-216. https://doi.org/10.1080/10641955.2019.1647232

Vancouver

Igonina TN, Ragaeva DS, Petrova OM, Rozkova IN, Brusentsev EY, Amstislavsky SY. Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats. Hypertension in pregnancy. 2019 Oct 2;38(4):208-216. doi: 10.1080/10641955.2019.1647232

Author

Igonina, Tatyana N. ; Ragaeva, Diana S. ; Petrova, Olga M. et al. / Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats. In: Hypertension in pregnancy. 2019 ; Vol. 38, No. 4. pp. 208-216.

BibTeX

@article{e1a6d7370cf64a3792ede2ee4756ebc4,
title = "Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats",
abstract = "Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female offspring. When ET was accompanied with in vitro culture in R1ECM, not only the female offspring, but also males demonstrated alleviation of hypertension. Conclusions: IVC at the preimplantation embryo stage affected the manifestation of hypertension in the adult ISIAH offspring.",
keywords = "culture, blood pressure, embryo transfer, hypertensive rats, offspring neurodevelopment, In vitro culture, SEX, VASCULAR DYSFUNCTION, BOVINE EMBRYOS, FOLLOW-UP, PRENATAL STRESS, BLOOD-PRESSURE, ASSISTED REPRODUCTION, GENE-EXPRESSION, REPRODUCTIVE TECHNOLOGIES, GENDER-DIFFERENCES",
author = "Igonina, {Tatyana N.} and Ragaeva, {Diana S.} and Petrova, {Olga M.} and Rozkova, {Irina N.} and Brusentsev, {Eugeny Yu} and Amstislavsky, {Sergey Ya}",
year = "2019",
month = oct,
day = "2",
doi = "10.1080/10641955.2019.1647232",
language = "English",
volume = "38",
pages = "208--216",
journal = "Hypertension in pregnancy",
issn = "1525-6065",
publisher = "Informa Healthcare",
number = "4",

}

RIS

TY - JOUR

T1 - Effects of in vitro culture at the preimplantation embryo stage on early development and hypertension in ISIAH rats

AU - Igonina, Tatyana N.

AU - Ragaeva, Diana S.

AU - Petrova, Olga M.

AU - Rozkova, Irina N.

AU - Brusentsev, Eugeny Yu

AU - Amstislavsky, Sergey Ya

PY - 2019/10/2

Y1 - 2019/10/2

N2 - Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female offspring. When ET was accompanied with in vitro culture in R1ECM, not only the female offspring, but also males demonstrated alleviation of hypertension. Conclusions: IVC at the preimplantation embryo stage affected the manifestation of hypertension in the adult ISIAH offspring.

AB - Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female offspring. When ET was accompanied with in vitro culture in R1ECM, not only the female offspring, but also males demonstrated alleviation of hypertension. Conclusions: IVC at the preimplantation embryo stage affected the manifestation of hypertension in the adult ISIAH offspring.

KW - culture

KW - blood pressure

KW - embryo transfer

KW - hypertensive rats

KW - offspring neurodevelopment

KW - In vitro culture

KW - SEX

KW - VASCULAR DYSFUNCTION

KW - BOVINE EMBRYOS

KW - FOLLOW-UP

KW - PRENATAL STRESS

KW - BLOOD-PRESSURE

KW - ASSISTED REPRODUCTION

KW - GENE-EXPRESSION

KW - REPRODUCTIVE TECHNOLOGIES

KW - GENDER-DIFFERENCES

UR - http://www.scopus.com/inward/record.url?scp=85072992693&partnerID=8YFLogxK

U2 - 10.1080/10641955.2019.1647232

DO - 10.1080/10641955.2019.1647232

M3 - Article

C2 - 31364410

AN - SCOPUS:85072992693

VL - 38

SP - 208

EP - 216

JO - Hypertension in pregnancy

JF - Hypertension in pregnancy

SN - 1525-6065

IS - 4

ER -

ID: 21859491