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Dominant subtype switch in avian influenza viruses during 2016–2019 in China. / Bi, Yuhai; Li, Juan; Li, Shanqin et al.

In: Nature Communications, Vol. 11, No. 1, 5909, 12.2020.

Research output: Contribution to journal › Article › peer-review

Harvard

Bi, Y, Li, J, Li, S, Fu, G, Jin, T, Zhang, C, Yang, Y, Ma, Z, Tian, W, Li, J, Xiao, S, Li, L, Yin, R, Zhang, Y, Wang, L, Qin, Y, Yao, Z, Meng, F, Hu, D, Li, D, Wong, G, Liu, F, Lv, N, Wang, L, Fu, L, Yang, Y, Peng, Y, Ma, J, Sharshov, K, Shestopalov, A, Gulyaeva, M, Gao, GF, Chen, J, Shi, Y, Liu, WJ, Chu, D, Huang, Y, Liu, Y, Liu, L, Liu, W, Chen, Q & Shi, W 2020, 'Dominant subtype switch in avian influenza viruses during 2016–2019 in China', Nature Communications, vol. 11, no. 1, 5909. https://doi.org/10.1038/s41467-020-19671-3

APA

Bi, Y., Li, J., Li, S., Fu, G., Jin, T., Zhang, C., Yang, Y., Ma, Z., Tian, W., Li, J., Xiao, S., Li, L., Yin, R., Zhang, Y., Wang, L., Qin, Y., Yao, Z., Meng, F., Hu, D., ... Shi, W. (2020). Dominant subtype switch in avian influenza viruses during 2016–2019 in China. Nature Communications, 11(1), [5909]. https://doi.org/10.1038/s41467-020-19671-3

Vancouver

Bi Y, Li J, Li S, Fu G, Jin T, Zhang C et al. Dominant subtype switch in avian influenza viruses during 2016–2019 in China. Nature Communications. 2020 Dec;11(1):5909. doi: 10.1038/s41467-020-19671-3

Author

Bi, Yuhai ; Li, Juan ; Li, Shanqin et al. / Dominant subtype switch in avian influenza viruses during 2016–2019 in China. In: Nature Communications. 2020 ; Vol. 11, No. 1.

BibTeX

@article{caee5c5ce1ea4383bc4ca53746fc9fef,
title = "Dominant subtype switch in avian influenza viruses during 2016–2019 in China",
abstract = "We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were collected from May 2016 to February 2019 in 23 provinces and municipalities in China. We identify 2048 AIV-positive samples and perform next generation sequencing. AIV-positive rates (12.73%) from samples had decreased substantially since 2016, compared to that during 2014–2016 (26.90%). Additionally, H9N2 has replaced H5N6 and H7N9 as the dominant AIV subtype in both chickens and ducks. Notably, novel reassortants and variants continually emerged and disseminated in avian populations, including H7N3, H9N9, H9N6 and H5N6 variants. Importantly, almost all of the H9 AIVs and many H7N9 and H6N2 strains prefer human-type receptors, posing an increased risk for human infections. In summary, our nation-wide surveillance highlights substantial changes in the circulation of AIVs since 2016, which greatly impacts the prevention and control of AIVs in China and worldwide.",
keywords = "RECEPTOR-BINDING SPECIFICITY, LIVE POULTRY MARKETS, A H7N9 VIRUS, HUMAN INFECTION, A(H7N9) VIRUS, HEMAGGLUTININ, EVOLUTION, H9N2, PATHOGENICITY, ADAPTATION",
author = "Yuhai Bi and Juan Li and Shanqin Li and Guanghua Fu and Tao Jin and Cheng Zhang and Yongchun Yang and Zhenghai Ma and Wenxia Tian and Jida Li and Shuqi Xiao and Liqiang Li and Renfu Yin and Yi Zhang and Lixin Wang and Yantao Qin and Zhongzi Yao and Fanyu Meng and Dongfang Hu and Delong Li and Gary Wong and Fei Liu and Na Lv and Liang Wang and Lifeng Fu and Yang Yang and Yun Peng and Jinmin Ma and Kirill Sharshov and Alexander Shestopalov and Marina Gulyaeva and Gao, {George F.} and Jianjun Chen and Yi Shi and Liu, {William J.} and Dong Chu and Yu Huang and Yingxia Liu and Lei Liu and Wenjun Liu and Quanjiao Chen and Weifeng Shi",
note = "Funding Information: This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (CAS; Grant No. XDB29010102), National Science and Technology Major Project (Grant No. 2018ZX10101004, 2018ZX10201001, 2018ZX10733403, and 2020ZX10001-016), Second Tibetan Plateau Scientific Expedition and Research Program (STEP; Grant No. 2019QZKK0304), National Key Research and Development Project of China (Grant No. 2016YFE0205800), National Natural Science Foundation of China (NSFC; Grant No. 31870163 and 32061123001), Shenzhen Science and Technology Research and Development Project (Grant No. JCYJ20180504165549581), RFBR Research Project (Grant No. 19-54-55004), Earmarked Fund for Modern Agro-industry Technology Research System (CARS-42) from the Ministry of Agriculture of P. R. China, Cooperative Innovation Project (The Shanghai Cooperation Organization Science and Technology Partnership Program; Grant No. 2017E01022), China-U.S. Collaborative Program on Emerging and Re-emerging Infectious Diseases (Grant No. 5U01IP001106-01), and Academic Promotion Programme of Shandong First Medical University (Grant No. 2019QL006 and 2019PT008). W.S. is supported by the Taishan Scholars program of Shandong Province (ts201511056). Y.B. is supported by the NSFC Outstanding Young Scholars (Grant No. 31822055), and Youth Innovation Promotion Association of CAS (Grant No. 2017122). Publisher Copyright: {\textcopyright} 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",
year = "2020",
month = dec,
doi = "10.1038/s41467-020-19671-3",
language = "English",
volume = "11",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Dominant subtype switch in avian influenza viruses during 2016–2019 in China

AU - Bi, Yuhai

AU - Li, Juan

AU - Li, Shanqin

AU - Fu, Guanghua

AU - Jin, Tao

AU - Zhang, Cheng

AU - Yang, Yongchun

AU - Ma, Zhenghai

AU - Tian, Wenxia

AU - Li, Jida

AU - Xiao, Shuqi

AU - Li, Liqiang

AU - Yin, Renfu

AU - Zhang, Yi

AU - Wang, Lixin

AU - Qin, Yantao

AU - Yao, Zhongzi

AU - Meng, Fanyu

AU - Hu, Dongfang

AU - Li, Delong

AU - Wong, Gary

AU - Liu, Fei

AU - Lv, Na

AU - Wang, Liang

AU - Fu, Lifeng

AU - Yang, Yang

AU - Peng, Yun

AU - Ma, Jinmin

AU - Sharshov, Kirill

AU - Shestopalov, Alexander

AU - Gulyaeva, Marina

AU - Gao, George F.

AU - Chen, Jianjun

AU - Shi, Yi

AU - Liu, William J.

AU - Chu, Dong

AU - Huang, Yu

AU - Liu, Yingxia

AU - Liu, Lei

AU - Liu, Wenjun

AU - Chen, Quanjiao

AU - Shi, Weifeng

N1 - Funding Information: This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (CAS; Grant No. XDB29010102), National Science and Technology Major Project (Grant No. 2018ZX10101004, 2018ZX10201001, 2018ZX10733403, and 2020ZX10001-016), Second Tibetan Plateau Scientific Expedition and Research Program (STEP; Grant No. 2019QZKK0304), National Key Research and Development Project of China (Grant No. 2016YFE0205800), National Natural Science Foundation of China (NSFC; Grant No. 31870163 and 32061123001), Shenzhen Science and Technology Research and Development Project (Grant No. JCYJ20180504165549581), RFBR Research Project (Grant No. 19-54-55004), Earmarked Fund for Modern Agro-industry Technology Research System (CARS-42) from the Ministry of Agriculture of P. R. China, Cooperative Innovation Project (The Shanghai Cooperation Organization Science and Technology Partnership Program; Grant No. 2017E01022), China-U.S. Collaborative Program on Emerging and Re-emerging Infectious Diseases (Grant No. 5U01IP001106-01), and Academic Promotion Programme of Shandong First Medical University (Grant No. 2019QL006 and 2019PT008). W.S. is supported by the Taishan Scholars program of Shandong Province (ts201511056). Y.B. is supported by the NSFC Outstanding Young Scholars (Grant No. 31822055), and Youth Innovation Promotion Association of CAS (Grant No. 2017122). Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/12

Y1 - 2020/12

N2 - We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were collected from May 2016 to February 2019 in 23 provinces and municipalities in China. We identify 2048 AIV-positive samples and perform next generation sequencing. AIV-positive rates (12.73%) from samples had decreased substantially since 2016, compared to that during 2014–2016 (26.90%). Additionally, H9N2 has replaced H5N6 and H7N9 as the dominant AIV subtype in both chickens and ducks. Notably, novel reassortants and variants continually emerged and disseminated in avian populations, including H7N3, H9N9, H9N6 and H5N6 variants. Importantly, almost all of the H9 AIVs and many H7N9 and H6N2 strains prefer human-type receptors, posing an increased risk for human infections. In summary, our nation-wide surveillance highlights substantial changes in the circulation of AIVs since 2016, which greatly impacts the prevention and control of AIVs in China and worldwide.

AB - We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were collected from May 2016 to February 2019 in 23 provinces and municipalities in China. We identify 2048 AIV-positive samples and perform next generation sequencing. AIV-positive rates (12.73%) from samples had decreased substantially since 2016, compared to that during 2014–2016 (26.90%). Additionally, H9N2 has replaced H5N6 and H7N9 as the dominant AIV subtype in both chickens and ducks. Notably, novel reassortants and variants continually emerged and disseminated in avian populations, including H7N3, H9N9, H9N6 and H5N6 variants. Importantly, almost all of the H9 AIVs and many H7N9 and H6N2 strains prefer human-type receptors, posing an increased risk for human infections. In summary, our nation-wide surveillance highlights substantial changes in the circulation of AIVs since 2016, which greatly impacts the prevention and control of AIVs in China and worldwide.

KW - RECEPTOR-BINDING SPECIFICITY

KW - LIVE POULTRY MARKETS

KW - A H7N9 VIRUS

KW - HUMAN INFECTION

KW - A(H7N9) VIRUS

KW - HEMAGGLUTININ

KW - EVOLUTION

KW - H9N2

KW - PATHOGENICITY

KW - ADAPTATION

UR - http://www.scopus.com/inward/record.url?scp=85096335550&partnerID=8YFLogxK

U2 - 10.1038/s41467-020-19671-3

DO - 10.1038/s41467-020-19671-3

M3 - Article

C2 - 33219213

AN - SCOPUS:85096335550

VL - 11

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 5909

ER -

ID: 26065501