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DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections. / Aliev, T. I.; Imatdinov, I. R.

In: Molecular Genetics, Microbiology and Virology, Vol. 40, No. 3, 1, 09.2025, p. 155-159.

Research output: Contribution to journalArticlepeer-review

Harvard

Aliev, TI & Imatdinov, IR 2025, 'DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections', Molecular Genetics, Microbiology and Virology, vol. 40, no. 3, 1, pp. 155-159. https://doi.org/10.3103/S089141682570017X

APA

Aliev, T. I., & Imatdinov, I. R. (2025). DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections. Molecular Genetics, Microbiology and Virology, 40(3), 155-159. [1]. https://doi.org/10.3103/S089141682570017X

Vancouver

Aliev TI, Imatdinov IR. DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections. Molecular Genetics, Microbiology and Virology. 2025 Sept;40(3):155-159. 1. doi: 10.3103/S089141682570017X

Author

Aliev, T. I. ; Imatdinov, I. R. / DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections. In: Molecular Genetics, Microbiology and Virology. 2025 ; Vol. 40, No. 3. pp. 155-159.

BibTeX

@article{a8005384c5ff40fdbdf7e2da096863ee,
title = "DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections",
abstract = "The use of base editors has been a significant achievement in the field of genomic editing. This approach involves the point-by-point editing of nitrogenous bases in the DNA of living cells. Since such an editing method does not involve the introduction of double-stranded breaks, such as the widespread CRISPR-Cas method, base editors are a promising tool in gene therapy by temporarily altering RNA bases or permanently altering DNA bases. Recent advances in the specificity, effectiveness, accuracy, and delivery of base editors open up new therapeutic possibilities for these technologies. It is assumed that the correction of single nucleotide mutations will become one of the directions of future precision medicine.",
keywords = "adenine base editor, cytosine base editor, gene therapy, review, viral infections, ОБЗОР, РЕДАКТОР ОСНОВАНИЙ ЦИТОЗИНА, РЕДАКТОР ОСНОВАНИЙ АДЕНИНА, ГЕННАЯ ТЕРАПИЯ, ВИРУСНЫЕ ИНФЕКЦИИ",
author = "Aliev, {T. I.} and Imatdinov, {I. R.}",
note = "DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections / T. I. Aliev, I. R. Imatdinov // Molecular Genetics, Microbiology and Virology. – 2025. – Vol. 40. - No. 3. – P. 155-159. – DOI 10.3103/S089141682570017X. – EDN QQJDPI. This study was supported by the Ministry of Science and Higher Education of the Russian Federation, “Federal Science and Technical Program for the Development of Genetic Technology (2019—2030),” agreement no. 075-15-2025-526.",
year = "2025",
month = sep,
doi = "10.3103/S089141682570017X",
language = "English",
volume = "40",
pages = "155--159",
journal = "Molecular Genetics, Microbiology and Virology",
issn = "0891-4168",
publisher = "Allerton Press Inc.",
number = "3",

}

RIS

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T1 - DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections

AU - Aliev, T. I.

AU - Imatdinov, I. R.

N1 - DNA Base Editors Are a Promising Tool for Gene Therapy of Human Viral Infections / T. I. Aliev, I. R. Imatdinov // Molecular Genetics, Microbiology and Virology. – 2025. – Vol. 40. - No. 3. – P. 155-159. – DOI 10.3103/S089141682570017X. – EDN QQJDPI. This study was supported by the Ministry of Science and Higher Education of the Russian Federation, “Federal Science and Technical Program for the Development of Genetic Technology (2019—2030),” agreement no. 075-15-2025-526.

PY - 2025/9

Y1 - 2025/9

N2 - The use of base editors has been a significant achievement in the field of genomic editing. This approach involves the point-by-point editing of nitrogenous bases in the DNA of living cells. Since such an editing method does not involve the introduction of double-stranded breaks, such as the widespread CRISPR-Cas method, base editors are a promising tool in gene therapy by temporarily altering RNA bases or permanently altering DNA bases. Recent advances in the specificity, effectiveness, accuracy, and delivery of base editors open up new therapeutic possibilities for these technologies. It is assumed that the correction of single nucleotide mutations will become one of the directions of future precision medicine.

AB - The use of base editors has been a significant achievement in the field of genomic editing. This approach involves the point-by-point editing of nitrogenous bases in the DNA of living cells. Since such an editing method does not involve the introduction of double-stranded breaks, such as the widespread CRISPR-Cas method, base editors are a promising tool in gene therapy by temporarily altering RNA bases or permanently altering DNA bases. Recent advances in the specificity, effectiveness, accuracy, and delivery of base editors open up new therapeutic possibilities for these technologies. It is assumed that the correction of single nucleotide mutations will become one of the directions of future precision medicine.

KW - adenine base editor

KW - cytosine base editor

KW - gene therapy

KW - review

KW - viral infections

KW - ОБЗОР

KW - РЕДАКТОР ОСНОВАНИЙ ЦИТОЗИНА

KW - РЕДАКТОР ОСНОВАНИЙ АДЕНИНА

KW - ГЕННАЯ ТЕРАПИЯ

KW - ВИРУСНЫЕ ИНФЕКЦИИ

UR - https://www.scopus.com/pages/publications/105026045605

UR - https://www.elibrary.ru/item.asp?id=87368354

UR - https://www.elibrary.ru/item.asp?id=82972004

UR - https://www.mendeley.com/catalogue/a77c7b5b-a75f-30fe-9951-c5c36475e7b9/

U2 - 10.3103/S089141682570017X

DO - 10.3103/S089141682570017X

M3 - Article

VL - 40

SP - 155

EP - 159

JO - Molecular Genetics, Microbiology and Virology

JF - Molecular Genetics, Microbiology and Virology

SN - 0891-4168

IS - 3

M1 - 1

ER -

ID: 75443806