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Diagnostic potential of cell-free DNA as a liquid biopsy marker. / Filipenko, M. L.

In: Bulletin of Russian State Medical University, Vol. 6, No. 4, 01.07.2017, p. 5-12.

Research output: Contribution to journal › Review article › peer-review

Harvard

Filipenko, ML 2017, 'Diagnostic potential of cell-free DNA as a liquid biopsy marker', Bulletin of Russian State Medical University, vol. 6, no. 4, pp. 5-12. https://doi.org/10.24075/brsmu.2017-04-01

APA

Filipenko, M. L. (2017). Diagnostic potential of cell-free DNA as a liquid biopsy marker. Bulletin of Russian State Medical University, 6(4), 5-12. https://doi.org/10.24075/brsmu.2017-04-01

Vancouver

Filipenko ML. Diagnostic potential of cell-free DNA as a liquid biopsy marker. Bulletin of Russian State Medical University. 2017 Jul 1;6(4):5-12. doi: 10.24075/brsmu.2017-04-01

Author

Filipenko, M. L. / Diagnostic potential of cell-free DNA as a liquid biopsy marker. In: Bulletin of Russian State Medical University. 2017 ; Vol. 6, No. 4. pp. 5-12.

BibTeX

@article{7e46c1bab53d43788a04eb3788863098,
title = "Diagnostic potential of cell-free DNA as a liquid biopsy marker",
abstract = "Cell-free DNA (cfDNA) was discovered in human blood plasma as early as the middle of the 20th century, but it was not until a few decades ago that knowledge of human genome and epigenome in health and pathology became sufficient and methods of nucleic acid analysis became more advanced to encourage active research of the diagnostic potential of cfDNA. The use of cfDNA as a diagnostic biomarker is conventionally referred to as liquid biopsy. The following review tells a story of cfDNA discovery, summarizes contemporary views on cfDNA sources inside the body and touches upon possible prognostic and diagnostic applications of cfDNA analysis in medicine, specifically in cancer and prenatal screening, prediction of implant failure and sepsis development.",
keywords = "Cancer screening, Cell-free DNA, CfDNA, Circulating DNA, Fetal DNA, Liquid biopsy, Prenatal screening",
author = "Filipenko, {M. L.}",
year = "2017",
month = jul,
day = "1",
doi = "10.24075/brsmu.2017-04-01",
language = "English",
volume = "6",
pages = "5--12",
journal = "Bulletin of Russian State Medical University",
issn = "2500-1094",
publisher = "Pirogov Russian National Research Medical University",
number = "4",

}

RIS

TY - JOUR

T1 - Diagnostic potential of cell-free DNA as a liquid biopsy marker

AU - Filipenko, M. L.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Cell-free DNA (cfDNA) was discovered in human blood plasma as early as the middle of the 20th century, but it was not until a few decades ago that knowledge of human genome and epigenome in health and pathology became sufficient and methods of nucleic acid analysis became more advanced to encourage active research of the diagnostic potential of cfDNA. The use of cfDNA as a diagnostic biomarker is conventionally referred to as liquid biopsy. The following review tells a story of cfDNA discovery, summarizes contemporary views on cfDNA sources inside the body and touches upon possible prognostic and diagnostic applications of cfDNA analysis in medicine, specifically in cancer and prenatal screening, prediction of implant failure and sepsis development.

AB - Cell-free DNA (cfDNA) was discovered in human blood plasma as early as the middle of the 20th century, but it was not until a few decades ago that knowledge of human genome and epigenome in health and pathology became sufficient and methods of nucleic acid analysis became more advanced to encourage active research of the diagnostic potential of cfDNA. The use of cfDNA as a diagnostic biomarker is conventionally referred to as liquid biopsy. The following review tells a story of cfDNA discovery, summarizes contemporary views on cfDNA sources inside the body and touches upon possible prognostic and diagnostic applications of cfDNA analysis in medicine, specifically in cancer and prenatal screening, prediction of implant failure and sepsis development.

KW - Cancer screening

KW - Cell-free DNA

KW - CfDNA

KW - Circulating DNA

KW - Fetal DNA

KW - Liquid biopsy

KW - Prenatal screening

UR - http://www.scopus.com/inward/record.url?scp=85032793922&partnerID=8YFLogxK

U2 - 10.24075/brsmu.2017-04-01

DO - 10.24075/brsmu.2017-04-01

M3 - Review article

AN - SCOPUS:85032793922

VL - 6

SP - 5

EP - 12

JO - Bulletin of Russian State Medical University

JF - Bulletin of Russian State Medical University

SN - 2500-1094

IS - 4

ER -

ID: 9722113