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Deconstructing age reprogramming. / Singh, Prim B.; Laktionov, Petr P.; Newman, Andrew G.

In: Journal of Biosciences, Vol. 44, No. 4, 106, 01.09.2019.

Research output: Contribution to journal › Review article › peer-review

Harvard

Singh, PB, Laktionov, PP & Newman, AG 2019, 'Deconstructing age reprogramming', Journal of Biosciences, vol. 44, no. 4, 106. https://doi.org/10.1007/s12038-019-9923-1

APA

Singh, P. B., Laktionov, P. P., & Newman, A. G. (2019). Deconstructing age reprogramming. Journal of Biosciences, 44(4), [106]. https://doi.org/10.1007/s12038-019-9923-1

Vancouver

Singh PB, Laktionov PP, Newman AG. Deconstructing age reprogramming. Journal of Biosciences. 2019 Sept 1;44(4):106. doi: 10.1007/s12038-019-9923-1

Author

Singh, Prim B. ; Laktionov, Petr P. ; Newman, Andrew G. / Deconstructing age reprogramming. In: Journal of Biosciences. 2019 ; Vol. 44, No. 4.

BibTeX

@article{305eeb5437dc4a40bb05eb3e3f7bf0df,
title = "Deconstructing age reprogramming",
abstract = "It has been proposed that age reprogramming enables old cells to be rejuvenated without passage through an embryonic stage (Singh and Zacouto in J Biosci 35:315–319, 2010). As such, age reprogramming stands apart from the induced pluripotent stem (iPS) and nuclear transfer-embryonic stem (NT-ES) cell therapies where histo-compatible cells are produced only after passage through an embryonic stage. It avoids many of the disadvantages associated with iPS and NT-ES cell therapies. Experimental evidence in support of age reprogramming is burgeoning. Here, we discuss possible new approaches to enhance age reprogramming, which will have considerable benefits for regenerative therapies.",
keywords = "Age reprogramming, eAge, Epigenetic clock, Epigenetic rejuvenation, iPS cells, reprogramming factors, CELLS, SENESCENT, CONVERSION, NEURONS, HALLMARKS, FIBROBLASTS",
author = "Singh, {Prim B.} and Laktionov, {Petr P.} and Newman, {Andrew G.}",
year = "2019",
month = sep,
day = "1",
doi = "10.1007/s12038-019-9923-1",
language = "English",
volume = "44",
journal = "Journal of Biosciences",
issn = "0250-5991",
publisher = "Springer India",
number = "4",

}

RIS

TY - JOUR

T1 - Deconstructing age reprogramming

AU - Singh, Prim B.

AU - Laktionov, Petr P.

AU - Newman, Andrew G.

PY - 2019/9/1

Y1 - 2019/9/1

N2 - It has been proposed that age reprogramming enables old cells to be rejuvenated without passage through an embryonic stage (Singh and Zacouto in J Biosci 35:315–319, 2010). As such, age reprogramming stands apart from the induced pluripotent stem (iPS) and nuclear transfer-embryonic stem (NT-ES) cell therapies where histo-compatible cells are produced only after passage through an embryonic stage. It avoids many of the disadvantages associated with iPS and NT-ES cell therapies. Experimental evidence in support of age reprogramming is burgeoning. Here, we discuss possible new approaches to enhance age reprogramming, which will have considerable benefits for regenerative therapies.

AB - It has been proposed that age reprogramming enables old cells to be rejuvenated without passage through an embryonic stage (Singh and Zacouto in J Biosci 35:315–319, 2010). As such, age reprogramming stands apart from the induced pluripotent stem (iPS) and nuclear transfer-embryonic stem (NT-ES) cell therapies where histo-compatible cells are produced only after passage through an embryonic stage. It avoids many of the disadvantages associated with iPS and NT-ES cell therapies. Experimental evidence in support of age reprogramming is burgeoning. Here, we discuss possible new approaches to enhance age reprogramming, which will have considerable benefits for regenerative therapies.

KW - Age reprogramming

KW - eAge

KW - Epigenetic clock

KW - Epigenetic rejuvenation

KW - iPS cells

KW - reprogramming factors

KW - CELLS

KW - SENESCENT

KW - CONVERSION

KW - NEURONS

KW - HALLMARKS

KW - FIBROBLASTS

UR - http://www.scopus.com/inward/record.url?scp=85070771586&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/de1ee469-de91-356a-b30c-332789bac2e1/

U2 - 10.1007/s12038-019-9923-1

DO - 10.1007/s12038-019-9923-1

M3 - Review article

AN - SCOPUS:85070771586

VL - 44

JO - Journal of Biosciences

JF - Journal of Biosciences

SN - 0250-5991

IS - 4

M1 - 106

ER -

ID: 21257011