Standard

Crystalline form of betulin : polymorphism or pseudopolymorphism? / Drebushchak, T. N.; Mikhailovskaya, A. V.; Drebushchak, V. A. et al.

In: Journal of Structural Chemistry, Vol. 61, No. 8, 01.08.2020, p. 1260-1266.

Research output: Contribution to journal › Article › peer-review

Harvard

Drebushchak, TN, Mikhailovskaya, AV, Drebushchak, VA, Mikhailenko, MA, Myz’, SA, Shakhtshneider, TP & Kuznetsova, SA 2020, 'Crystalline form of betulin: polymorphism or pseudopolymorphism?', Journal of Structural Chemistry, vol. 61, no. 8, pp. 1260-1266. https://doi.org/10.1134/S0022476620080119

APA

Drebushchak, T. N., Mikhailovskaya, A. V., Drebushchak, V. A., Mikhailenko, M. A., Myz’, S. A., Shakhtshneider, T. P., & Kuznetsova, S. A. (2020). Crystalline form of betulin: polymorphism or pseudopolymorphism? Journal of Structural Chemistry, 61(8), 1260-1266. https://doi.org/10.1134/S0022476620080119

Vancouver

Drebushchak TN, Mikhailovskaya AV, Drebushchak VA, Mikhailenko MA, Myz’ SA, Shakhtshneider TP et al. Crystalline form of betulin: polymorphism or pseudopolymorphism? Journal of Structural Chemistry. 2020 Aug 1;61(8):1260-1266. doi: 10.1134/S0022476620080119

Author

Drebushchak, T. N. ; Mikhailovskaya, A. V. ; Drebushchak, V. A. et al. / Crystalline form of betulin : polymorphism or pseudopolymorphism?. In: Journal of Structural Chemistry. 2020 ; Vol. 61, No. 8. pp. 1260-1266.

BibTeX

@article{9867e7a464b14119a4b0fe26a06a7ead,
title = "Crystalline form of betulin: polymorphism or pseudopolymorphism?",
abstract = "By recrystallization with different solvents as well as decomposition of betulin ethanol solvate at room temperature a new crystalline form of the biologically active compound betulin, namely hemihydrate of betulin, is obtained. By single crystal X-ray diffraction data the crystal structure of hemihydrate of betulin is determined. By powder X-ray thermodiffraction and differential scanning calorimetry it is found that when hemihydrate of betulin is heated to melting, Н2О molecules are removed and solid-phase transformations occur, which are related to the formation of an intermediate crystalline form andan orthorhombic modification of betulin.",
keywords = "betulin, polymorphism, pseudopolymorphism, solid-phase transformations, SOLVATOMORPHS, ISOSTRUCTURALITY, X-RAY",
author = "Drebushchak, {T. N.} and Mikhailovskaya, {A. V.} and Drebushchak, {V. A.} and Mikhailenko, {M. A.} and Myz{\textquoteright}, {S. A.} and Shakhtshneider, {T. P.} and Kuznetsova, {S. A.}",
year = "2020",
month = aug,
day = "1",
doi = "10.1134/S0022476620080119",
language = "English",
volume = "61",
pages = "1260--1266",
journal = "Journal of Structural Chemistry",
issn = "0022-4766",
publisher = "Springer GmbH & Co, Auslieferungs-Gesellschaf",
number = "8",

}

RIS

TY - JOUR

T1 - Crystalline form of betulin

T2 - polymorphism or pseudopolymorphism?

AU - Drebushchak, T. N.

AU - Mikhailovskaya, A. V.

AU - Drebushchak, V. A.

AU - Mikhailenko, M. A.

AU - Myz’, S. A.

AU - Shakhtshneider, T. P.

AU - Kuznetsova, S. A.

PY - 2020/8/1

Y1 - 2020/8/1

N2 - By recrystallization with different solvents as well as decomposition of betulin ethanol solvate at room temperature a new crystalline form of the biologically active compound betulin, namely hemihydrate of betulin, is obtained. By single crystal X-ray diffraction data the crystal structure of hemihydrate of betulin is determined. By powder X-ray thermodiffraction and differential scanning calorimetry it is found that when hemihydrate of betulin is heated to melting, Н2О molecules are removed and solid-phase transformations occur, which are related to the formation of an intermediate crystalline form andan orthorhombic modification of betulin.

AB - By recrystallization with different solvents as well as decomposition of betulin ethanol solvate at room temperature a new crystalline form of the biologically active compound betulin, namely hemihydrate of betulin, is obtained. By single crystal X-ray diffraction data the crystal structure of hemihydrate of betulin is determined. By powder X-ray thermodiffraction and differential scanning calorimetry it is found that when hemihydrate of betulin is heated to melting, Н2О molecules are removed and solid-phase transformations occur, which are related to the formation of an intermediate crystalline form andan orthorhombic modification of betulin.

KW - betulin

KW - polymorphism

KW - pseudopolymorphism

KW - solid-phase transformations

KW - SOLVATOMORPHS

KW - ISOSTRUCTURALITY

KW - X-RAY

UR - http://www.scopus.com/inward/record.url?scp=85091281374&partnerID=8YFLogxK

U2 - 10.1134/S0022476620080119

DO - 10.1134/S0022476620080119

M3 - Article

AN - SCOPUS:85091281374

VL - 61

SP - 1260

EP - 1266

JO - Journal of Structural Chemistry

JF - Journal of Structural Chemistry

SN - 0022-4766

IS - 8

ER -

ID: 25312584