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Cocrystals of betulin with adipic acid: preparation and thermal behavior. / Myz, S. A.; Mikhailenko, M. A.; Mikhailovskaya, A. V. et al.

In: Journal of Thermal Analysis and Calorimetry, Vol. 147, No. 15, 08.2022, p. 8235-8242.

Research output: Contribution to journal › Article › peer-review

Harvard

Myz, SA, Mikhailenko, MA, Mikhailovskaya, AV, Bulina, NV, Gerasimov, KB, Politov, AA, Kuznetsova, SA & Shakhtshneider, TP 2022, 'Cocrystals of betulin with adipic acid: preparation and thermal behavior', Journal of Thermal Analysis and Calorimetry, vol. 147, no. 15, pp. 8235-8242. https://doi.org/10.1007/s10973-021-11107-4

APA

Myz, S. A., Mikhailenko, M. A., Mikhailovskaya, A. V., Bulina, N. V., Gerasimov, K. B., Politov, A. A., Kuznetsova, S. A., & Shakhtshneider, T. P. (2022). Cocrystals of betulin with adipic acid: preparation and thermal behavior. Journal of Thermal Analysis and Calorimetry, 147(15), 8235-8242. https://doi.org/10.1007/s10973-021-11107-4

Vancouver

Myz SA, Mikhailenko MA, Mikhailovskaya AV, Bulina NV, Gerasimov KB, Politov AA et al. Cocrystals of betulin with adipic acid: preparation and thermal behavior. Journal of Thermal Analysis and Calorimetry. 2022 Aug;147(15):8235-8242. doi: 10.1007/s10973-021-11107-4

Author

Myz, S. A. ; Mikhailenko, M. A. ; Mikhailovskaya, A. V. et al. / Cocrystals of betulin with adipic acid: preparation and thermal behavior. In: Journal of Thermal Analysis and Calorimetry. 2022 ; Vol. 147, No. 15. pp. 8235-8242.

BibTeX

@article{27177aba54214c0b8280180096d7e76a,
title = "Cocrystals of betulin with adipic acid: preparation and thermal behavior",
abstract = "The cocrystal of betulin (BE) with adipic acid (AA) was prepared using a liquid-assisted grinding method. The formation of BE-AA cocrystal was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. It was assumed that 1:1 BE-AA cocrystal hydrate was formed when liquid-assisted grinding was carried out using water-miscible liquids in which the solubility of adipic acid was higher than in others. The cocrystal hydrate was stable under room temperature and rather high relative humidity. Nevertheless, the betulin–adipic acid cocrystal was found to decompose under heating after the loss of water molecules, followed by phase transformation. An anhydrous BE-AA cocrystal was also prepared by the BE-AA physical mixture heating up to the point of adipic acid melting.",
keywords = "Adipic acid, Betulin, Co-grinding, Cocrystal hydrate, Cocrystal stability",
author = "Myz, {S. A.} and Mikhailenko, {M. A.} and Mikhailovskaya, {A. V.} and Bulina, {N. V.} and Gerasimov, {K. B.} and Politov, {A. A.} and Kuznetsova, {S. A.} and Shakhtshneider, {T. P.}",
note = "Funding Information: The research was carried out within the State Assignments to ISSCM SB RAS (project No. FWUS-2021-0009) and ICCT SB RAS (Project No. 0287-2021-0017). The authors are grateful to E. Losev for recording the FTIR spectra. Publisher Copyright: {\textcopyright} 2021, Akad{\'e}miai Kiad{\'o}, Budapest, Hungary.",
year = "2022",
month = aug,
doi = "10.1007/s10973-021-11107-4",
language = "English",
volume = "147",
pages = "8235--8242",
journal = "Journal of Thermal Analysis and Calorimetry",
issn = "1388-6150",
publisher = "Springer Nature",
number = "15",

}

RIS

TY - JOUR

T1 - Cocrystals of betulin with adipic acid: preparation and thermal behavior

AU - Myz, S. A.

AU - Mikhailenko, M. A.

AU - Mikhailovskaya, A. V.

AU - Bulina, N. V.

AU - Gerasimov, K. B.

AU - Politov, A. A.

AU - Kuznetsova, S. A.

AU - Shakhtshneider, T. P.

N1 - Funding Information: The research was carried out within the State Assignments to ISSCM SB RAS (project No. FWUS-2021-0009) and ICCT SB RAS (Project No. 0287-2021-0017). The authors are grateful to E. Losev for recording the FTIR spectra. Publisher Copyright: © 2021, Akadémiai Kiadó, Budapest, Hungary.

PY - 2022/8

Y1 - 2022/8

N2 - The cocrystal of betulin (BE) with adipic acid (AA) was prepared using a liquid-assisted grinding method. The formation of BE-AA cocrystal was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. It was assumed that 1:1 BE-AA cocrystal hydrate was formed when liquid-assisted grinding was carried out using water-miscible liquids in which the solubility of adipic acid was higher than in others. The cocrystal hydrate was stable under room temperature and rather high relative humidity. Nevertheless, the betulin–adipic acid cocrystal was found to decompose under heating after the loss of water molecules, followed by phase transformation. An anhydrous BE-AA cocrystal was also prepared by the BE-AA physical mixture heating up to the point of adipic acid melting.

AB - The cocrystal of betulin (BE) with adipic acid (AA) was prepared using a liquid-assisted grinding method. The formation of BE-AA cocrystal was confirmed by powder X-ray diffraction, IR spectroscopy and thermal analysis methods. It was assumed that 1:1 BE-AA cocrystal hydrate was formed when liquid-assisted grinding was carried out using water-miscible liquids in which the solubility of adipic acid was higher than in others. The cocrystal hydrate was stable under room temperature and rather high relative humidity. Nevertheless, the betulin–adipic acid cocrystal was found to decompose under heating after the loss of water molecules, followed by phase transformation. An anhydrous BE-AA cocrystal was also prepared by the BE-AA physical mixture heating up to the point of adipic acid melting.

KW - Adipic acid

KW - Betulin

KW - Co-grinding

KW - Cocrystal hydrate

KW - Cocrystal stability

UR - http://www.scopus.com/inward/record.url?scp=85119507735&partnerID=8YFLogxK

U2 - 10.1007/s10973-021-11107-4

DO - 10.1007/s10973-021-11107-4

M3 - Article

AN - SCOPUS:85119507735

VL - 147

SP - 8235

EP - 8242

JO - Journal of Thermal Analysis and Calorimetry

JF - Journal of Thermal Analysis and Calorimetry

SN - 1388-6150

IS - 15

ER -

ID: 34707247