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Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. / Shkurupy, V. A.; Potapova, O. V.; Mezhevalova, A. S. et al.

In: Bulletin of Experimental Biology and Medicine, Vol. 166, No. 3, 15.01.2019, p. 358-363.

Research output: Contribution to journal › Article › peer-review

Harvard

Shkurupy, VA, Potapova, OV, Mezhevalova, AS, Cherdantseva, LA, Kovner, AV & Shestopalov, AM 2019, 'Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1', Bulletin of Experimental Biology and Medicine, vol. 166, no. 3, pp. 358-363. https://doi.org/10.1007/s10517-019-04350-1

APA

Shkurupy, V. A., Potapova, O. V., Mezhevalova, A. S., Cherdantseva, L. A., Kovner, A. V., & Shestopalov, A. M. (2019). Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. Bulletin of Experimental Biology and Medicine, 166(3), 358-363. https://doi.org/10.1007/s10517-019-04350-1

Vancouver

Shkurupy VA, Potapova OV, Mezhevalova AS, Cherdantseva LA, Kovner AV, Shestopalov AM. Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. Bulletin of Experimental Biology and Medicine. 2019 Jan 15;166(3):358-363. doi: 10.1007/s10517-019-04350-1

Author

Shkurupy, V. A. ; Potapova, O. V. ; Mezhevalova, A. S. et al. / Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. In: Bulletin of Experimental Biology and Medicine. 2019 ; Vol. 166, No. 3. pp. 358-363.

BibTeX

@article{1201c3b11de1406a834992e88e29678c,
title = "Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1",
abstract = "Changes in the kidney structure in outbred and inbred male BALB/c mice were analyzed in the acute period after infection with influenza viruses A/H5N1 (10 MLD50; 10 days) and A/H1N1 (1 MLD50; 30 days). Antibodies to influenza viruses of both strains were most often expressed by endothelial cells of the glomeruli and arterioles and were rarely expressed by mesangiocytes and tubule epithelial cells. In the kidney, destructive processes induced by viruses and by ischemia due to massive blood vessel thrombosis. Mesangiocytes expressed factors, indicating that they could be qualified as M1 and M2 macrophages. Kidney destruction was more significant after infection of mice with the A/H5N1 virus, but in both experiments cell infiltrates were actually absent, probably due to blood vessel thrombosis and limited possibility of migration of mononuclear phagocytes and lymphocytes to the kidney.",
keywords = "influenza A virus, kidney damage, M1/M2 macrophage polarization, mesangiocytes",
author = "Shkurupy, {V. A.} and Potapova, {O. V.} and Mezhevalova, {A. S.} and Cherdantseva, {L. A.} and Kovner, {A. V.} and Shestopalov, {A. M.}",
note = "Publisher Copyright: {\textcopyright} 2019, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2019",
month = jan,
day = "15",
doi = "10.1007/s10517-019-04350-1",
language = "English",
volume = "166",
pages = "358--363",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer New York",
number = "3",

}

RIS

TY - JOUR

T1 - Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1

AU - Shkurupy, V. A.

AU - Potapova, O. V.

AU - Mezhevalova, A. S.

AU - Cherdantseva, L. A.

AU - Kovner, A. V.

AU - Shestopalov, A. M.

N1 - Publisher Copyright: © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

PY - 2019/1/15

Y1 - 2019/1/15

N2 - Changes in the kidney structure in outbred and inbred male BALB/c mice were analyzed in the acute period after infection with influenza viruses A/H5N1 (10 MLD50; 10 days) and A/H1N1 (1 MLD50; 30 days). Antibodies to influenza viruses of both strains were most often expressed by endothelial cells of the glomeruli and arterioles and were rarely expressed by mesangiocytes and tubule epithelial cells. In the kidney, destructive processes induced by viruses and by ischemia due to massive blood vessel thrombosis. Mesangiocytes expressed factors, indicating that they could be qualified as M1 and M2 macrophages. Kidney destruction was more significant after infection of mice with the A/H5N1 virus, but in both experiments cell infiltrates were actually absent, probably due to blood vessel thrombosis and limited possibility of migration of mononuclear phagocytes and lymphocytes to the kidney.

AB - Changes in the kidney structure in outbred and inbred male BALB/c mice were analyzed in the acute period after infection with influenza viruses A/H5N1 (10 MLD50; 10 days) and A/H1N1 (1 MLD50; 30 days). Antibodies to influenza viruses of both strains were most often expressed by endothelial cells of the glomeruli and arterioles and were rarely expressed by mesangiocytes and tubule epithelial cells. In the kidney, destructive processes induced by viruses and by ischemia due to massive blood vessel thrombosis. Mesangiocytes expressed factors, indicating that they could be qualified as M1 and M2 macrophages. Kidney destruction was more significant after infection of mice with the A/H5N1 virus, but in both experiments cell infiltrates were actually absent, probably due to blood vessel thrombosis and limited possibility of migration of mononuclear phagocytes and lymphocytes to the kidney.

KW - influenza A virus

KW - kidney damage

KW - M1/M2 macrophage polarization

KW - mesangiocytes

UR - http://www.scopus.com/inward/record.url?scp=85059865310&partnerID=8YFLogxK

U2 - 10.1007/s10517-019-04350-1

DO - 10.1007/s10517-019-04350-1

M3 - Article

C2 - 30627911

AN - SCOPUS:85059865310

VL - 166

SP - 358

EP - 363

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 3

ER -

ID: 18143237