TY - GEN

T1 - Breath signatures of cerebral palsy patients revealed with mid-infrared FTIR spectroscopy

AU - Maiti, Kiran Sankar

AU - Roy, Susmita

AU - Lampe, Renée

AU - Apolonski, Alexander

PY - 2019/6

Y1 - 2019/6

N2 - In the absence of 'broadband' objective medical diagnostics, photonics technologies are now considered as a promising way to establish it. For example, being applied to human breath, under right conditions they should allow for unambiguous identification of metabolites circulating in blood and released in lungs alveoli as volatile organic compounds (VOCs). Nowadays, tremendous progress is achieved in developing laser-based mid-infrared spectrometers highly sensitive to VOCs [1,2]. Still, the spectral range covered by the laser spectrometers demonstrated so far, and signal-to-nose ratio (SNR) are not superior to conventional FTIR spectrometers based on thermal source. A significant amount of water vapour in breath is another, though general for all techniques, severe problem for VOCs detection. In addition to the detection, data analysis should be advanced in order to accurately compare healthy and diseased cohorts under study.

AB - In the absence of 'broadband' objective medical diagnostics, photonics technologies are now considered as a promising way to establish it. For example, being applied to human breath, under right conditions they should allow for unambiguous identification of metabolites circulating in blood and released in lungs alveoli as volatile organic compounds (VOCs). Nowadays, tremendous progress is achieved in developing laser-based mid-infrared spectrometers highly sensitive to VOCs [1,2]. Still, the spectral range covered by the laser spectrometers demonstrated so far, and signal-to-nose ratio (SNR) are not superior to conventional FTIR spectrometers based on thermal source. A significant amount of water vapour in breath is another, though general for all techniques, severe problem for VOCs detection. In addition to the detection, data analysis should be advanced in order to accurately compare healthy and diseased cohorts under study.

UR - http://www.scopus.com/inward/record.url?scp=85074633642&partnerID=8YFLogxK

U2 - 10.1109/CLEOE-EQEC.2019.8872309

DO - 10.1109/CLEOE-EQEC.2019.8872309

M3 - Conference contribution

AN - SCOPUS:85074633642

T3 - 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

BT - 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019

Y2 - 23 June 2019 through 27 June 2019

ER -