Research output: Contribution to journal › Review article › peer-review
Bioinspired Non-Heme Mn Catalysts for Regio- and Stereoselective Oxyfunctionalizations with H2O2. / Ottenbacher, Roman V; Bryliakova, Anna A; Kurganskii, Vladimir I et al.
In: Chemistry - A European Journal, Vol. 29, No. 66, e202302772, 24.11.2023, p. 1-16.Research output: Contribution to journal › Review article › peer-review
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TY - JOUR
T1 - Bioinspired Non-Heme Mn Catalysts for Regio- and Stereoselective Oxyfunctionalizations with H2O2
AU - Ottenbacher, Roman V
AU - Bryliakova, Anna A
AU - Kurganskii, Vladimir I
AU - Prikhodchenko, Petr V
AU - Medvedev, Alexander G
AU - Bryliakov, Konstantin Petrovich
N1 - Acknowledgments RVO, AAB, VIK, KPB thank the Russian Science Foundation (grant 20-13-00032) for financial support. The authors thank Dr. O. Y. Lyakin for providing the ligand for the synthesis of complex 17. AAB thanks the access to the supercomputer facilities of the Computing Centre of Novosibirsk State University. © 2023 Wiley-VCH GmbH.
PY - 2023/11/24
Y1 - 2023/11/24
N2 - In recent years, metalloenzymes-mediated highly selective oxidations of organic substrates under mild conditions have been inspiration for developing synthetic bioinspired catalyst systems, capable of conducting such processes in the laboratory (and, in the future, in industry), relying on easy-to-handle and environmentally benign oxidants such as H2O2. To date, non-heme manganese complexes with chiral bis-amino-bis-pyridylmethyl and structurally related ligands are considered as possessing the highest synthetic potential, having demonstrated the ability to mediate a variety of chemo- and stereoselective oxidative transformations, such as epoxidations, C(sp3)-H hydroxylations and ketonizations, oxidative desymmetrizations, kinetic resolutions, etc. Furthermore, in the past few years non-heme Mn based catalysts have become the major platform for studies focused on getting insight into the molecular mechanisms of oxidant activation and (stereo)selective oxygen transfer, testing non-traditional hydroperoxide oxidants, engineering catalytic sites with enzyme-like substrate recognition-based selectivity, exploration of catalytic regioselectivity trends in the oxidation of biologically active substrates of natural origin. This contribution summarizes the progress in manganese catalyzed C-H oxygenative transformations of organic substrates, achieved essentially in the past 5 years (late 2018-2023).
AB - In recent years, metalloenzymes-mediated highly selective oxidations of organic substrates under mild conditions have been inspiration for developing synthetic bioinspired catalyst systems, capable of conducting such processes in the laboratory (and, in the future, in industry), relying on easy-to-handle and environmentally benign oxidants such as H2O2. To date, non-heme manganese complexes with chiral bis-amino-bis-pyridylmethyl and structurally related ligands are considered as possessing the highest synthetic potential, having demonstrated the ability to mediate a variety of chemo- and stereoselective oxidative transformations, such as epoxidations, C(sp3)-H hydroxylations and ketonizations, oxidative desymmetrizations, kinetic resolutions, etc. Furthermore, in the past few years non-heme Mn based catalysts have become the major platform for studies focused on getting insight into the molecular mechanisms of oxidant activation and (stereo)selective oxygen transfer, testing non-traditional hydroperoxide oxidants, engineering catalytic sites with enzyme-like substrate recognition-based selectivity, exploration of catalytic regioselectivity trends in the oxidation of biologically active substrates of natural origin. This contribution summarizes the progress in manganese catalyzed C-H oxygenative transformations of organic substrates, achieved essentially in the past 5 years (late 2018-2023).
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85174191155&origin=inward&txGid=b958cf734ca488f5ed375422255ec59f
UR - https://www.mendeley.com/catalogue/d2b65bd7-a4af-3927-87ea-fb10b5dbed2a/
U2 - 10.1002/chem.202302772
DO - 10.1002/chem.202302772
M3 - Review article
C2 - 37642264
VL - 29
SP - 1
EP - 16
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
IS - 66
M1 - e202302772
ER -
ID: 55271129