Standard

Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics : Effect of filler and polymer crystallinity. / Demina, Varvara A.; Krasheninnikov, Sergei V.; Buzin, Alexander I. et al.

In: Materials Science and Engineering C, Vol. 112, 110813, 07.2020.

Research output: Contribution to journal › Article › peer-review

Harvard

Demina, VA, Krasheninnikov, SV, Buzin, AI, Kamyshinsky, RA, Sadovskaya, NV, Goncharov, EN, Zhukova, NA, Khvostov, MV, Pavlova, AV, Tolstikova, TG, Sedush, NG & Chvalun, SN 2020, 'Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics: Effect of filler and polymer crystallinity', Materials Science and Engineering C, vol. 112, 110813. https://doi.org/10.1016/j.msec.2020.110813

APA

Demina, V. A., Krasheninnikov, S. V., Buzin, A. I., Kamyshinsky, R. A., Sadovskaya, N. V., Goncharov, E. N., Zhukova, N. A., Khvostov, M. V., Pavlova, A. V., Tolstikova, T. G., Sedush, N. G., & Chvalun, S. N. (2020). Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics: Effect of filler and polymer crystallinity. Materials Science and Engineering C, 112, [110813]. https://doi.org/10.1016/j.msec.2020.110813

Vancouver

Demina VA, Krasheninnikov SV, Buzin AI, Kamyshinsky RA, Sadovskaya NV, Goncharov EN et al. Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics: Effect of filler and polymer crystallinity. Materials Science and Engineering C. 2020 Jul;112:110813. doi: 10.1016/j.msec.2020.110813

Author

Demina, Varvara A. ; Krasheninnikov, Sergei V. ; Buzin, Alexander I. et al. / Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics : Effect of filler and polymer crystallinity. In: Materials Science and Engineering C. 2020 ; Vol. 112.

BibTeX

@article{9b79ee9ea31248968c4fc1a65fa80d56,
title = "Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics: Effect of filler and polymer crystallinity",
abstract = "Biodegradable poly(L-lactide)/calcium phosphate composites are promising materials for fabrication of bone fixation implants with improved properties. Multistage compounding was proposed as an efficient method for the preparation of biodegradable poly(L-lactide)/calcium phosphate composites with submicron filler dispersion and mechanical characteristics similar to native bone. The improvement of the characteristics is caused both by the filler itself and by the increase of polymer crystallinity due to the nucleation effect. The technique allows to fabricate biodegradable composites with controlled properties by varying concentration and type of the filler as well as degree of PLLA matrix crystallinity. Animal studies revealed that all the composites were biocompatible and non-toxic.",
keywords = "Biodegradable polymers, Bone tissue engineering, Hydroxyapatite, Polylactide, Polymer composites, SURFACE-MODIFIED HYDROXYAPATITE, TRICALCIUM PHOSPHATE, IMPLANTS, MECHANICAL-PROPERTIES, PHASE, DEGRADATION, BONE, SCAFFOLDS, NANOTECHNOLOGY",
author = "Demina, {Varvara A.} and Krasheninnikov, {Sergei V.} and Buzin, {Alexander I.} and Kamyshinsky, {Roman A.} and Sadovskaya, {Natalya V.} and Goncharov, {Evgeny N.} and Zhukova, {Natalya A.} and Khvostov, {Mikhail V.} and Pavlova, {Alla V.} and Tolstikova, {Tatjana G.} and Sedush, {Nikita G.} and Chvalun, {Sergei N.}",
note = "Copyright {\textcopyright} 2020. Published by Elsevier B.V.",
year = "2020",
month = jul,
doi = "10.1016/j.msec.2020.110813",
language = "English",
volume = "112",
journal = "Materials Science and Engineering C",
issn = "0928-4931",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Biodegradable poly(L-lactide)/calcium phosphate composites with improved properties for orthopedics

T2 - Effect of filler and polymer crystallinity

AU - Demina, Varvara A.

AU - Krasheninnikov, Sergei V.

AU - Buzin, Alexander I.

AU - Kamyshinsky, Roman A.

AU - Sadovskaya, Natalya V.

AU - Goncharov, Evgeny N.

AU - Zhukova, Natalya A.

AU - Khvostov, Mikhail V.

AU - Pavlova, Alla V.

AU - Tolstikova, Tatjana G.

AU - Sedush, Nikita G.

AU - Chvalun, Sergei N.

N1 - Copyright © 2020. Published by Elsevier B.V.

PY - 2020/7

Y1 - 2020/7

N2 - Biodegradable poly(L-lactide)/calcium phosphate composites are promising materials for fabrication of bone fixation implants with improved properties. Multistage compounding was proposed as an efficient method for the preparation of biodegradable poly(L-lactide)/calcium phosphate composites with submicron filler dispersion and mechanical characteristics similar to native bone. The improvement of the characteristics is caused both by the filler itself and by the increase of polymer crystallinity due to the nucleation effect. The technique allows to fabricate biodegradable composites with controlled properties by varying concentration and type of the filler as well as degree of PLLA matrix crystallinity. Animal studies revealed that all the composites were biocompatible and non-toxic.

AB - Biodegradable poly(L-lactide)/calcium phosphate composites are promising materials for fabrication of bone fixation implants with improved properties. Multistage compounding was proposed as an efficient method for the preparation of biodegradable poly(L-lactide)/calcium phosphate composites with submicron filler dispersion and mechanical characteristics similar to native bone. The improvement of the characteristics is caused both by the filler itself and by the increase of polymer crystallinity due to the nucleation effect. The technique allows to fabricate biodegradable composites with controlled properties by varying concentration and type of the filler as well as degree of PLLA matrix crystallinity. Animal studies revealed that all the composites were biocompatible and non-toxic.

KW - Biodegradable polymers

KW - Bone tissue engineering

KW - Hydroxyapatite

KW - Polylactide

KW - Polymer composites

KW - SURFACE-MODIFIED HYDROXYAPATITE

KW - TRICALCIUM PHOSPHATE

KW - IMPLANTS

KW - MECHANICAL-PROPERTIES

KW - PHASE

KW - DEGRADATION

KW - BONE

KW - SCAFFOLDS

KW - NANOTECHNOLOGY

UR - http://www.scopus.com/inward/record.url?scp=85083000529&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2020.110813

DO - 10.1016/j.msec.2020.110813

M3 - Article

C2 - 32409026

AN - SCOPUS:85083000529

VL - 112

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

M1 - 110813

ER -

ID: 23995894