Biocatalytic Heterogeneous Processes of the Esterification of Saturated Fatty Acids with Aliphatic Alcohols

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Biocatalytic Heterogeneous Processes of the Esterification of Saturated Fatty Acids with Aliphatic Alcohols. / Kovalenko, G. A.; Perminova, L. V.; Beklemishev, A. B. et al.

In: Catalysis in Industry, Vol. 10, No. 1, 01.01.2018, p. 68-74.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{7e4e4c6740bc461ba858c3eb40f2aa9d,

title = "Biocatalytic Heterogeneous Processes of the Esterification of Saturated Fatty Acids with Aliphatic Alcohols",

abstract = "Heterogeneous biocatalysts prepared by immobilizing a recombinant lipase from Thermomyces lanuginosus on mesoporous inorganic supports—silica (SiO2), alumina (Al2O3), and titania (TiO2)—are comparatively studied in the esterification of fatty acids with aliphatic alcohols. It is found that the T. lanuginosus lipase adsorbed on silica has the highest esterifying activity, while the lipase adsorbed on titania is completely inactivated. SiO2-based catalysts have high activity and stability in the esterification of saturated fatty acids containing 4–18 carbon atoms (C4–C18) with aliphatic alcohols (C5–C16) in organic solvents (hexane and diethyl ether). The catalysts operate in this reaction for several tens of reaction cycles (>40) without loss of activity. The recombinant rPichia/lip lipase immobilized on silica exhibits the most pronounced specificity for its first substrate, a fatty acid. For instance, the rate of synthesis for esters of low molecular weight acids (С4–С6) is three to four times slower than for the esters of acids with more than seven carbon atoms. The catalyst has a relatively broad specificity for the second substrate, an aliphatic alcohol. It is found that the ester of enanthic acid (C7:0) and butanol (C4) is synthesized at the maximum rate.",

keywords = "aliphatic alcohols, biocatalysts, esterification, fatty acids, recombinant lipase, ESTERS, MEDIA, LIPASE, SILICA, SELECTIVITY",

author = "Kovalenko, {G. A.} and Perminova, {L. V.} and Beklemishev, {A. B.} and Mamaev, {A. L.} and Patrushev, {Yu V.}",

note = "Publisher Copyright: {\textcopyright} 2018, Pleiades Publishing, Ltd.",

year = "2018",

month = jan,

day = "1",

doi = "10.1134/S2070050418010075",

language = "English",

volume = "10",

pages = "68--74",

journal = "Catalysis in Industry",

issn = "2070-0504",

publisher = "Maik Nauka-Interperiodica Publishing",

number = "1",

}

RIS

TY - JOUR

T1 - Biocatalytic Heterogeneous Processes of the Esterification of Saturated Fatty Acids with Aliphatic Alcohols

AU - Kovalenko, G. A.

AU - Perminova, L. V.

AU - Beklemishev, A. B.

AU - Mamaev, A. L.

AU - Patrushev, Yu V.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Heterogeneous biocatalysts prepared by immobilizing a recombinant lipase from Thermomyces lanuginosus on mesoporous inorganic supports—silica (SiO2), alumina (Al2O3), and titania (TiO2)—are comparatively studied in the esterification of fatty acids with aliphatic alcohols. It is found that the T. lanuginosus lipase adsorbed on silica has the highest esterifying activity, while the lipase adsorbed on titania is completely inactivated. SiO2-based catalysts have high activity and stability in the esterification of saturated fatty acids containing 4–18 carbon atoms (C4–C18) with aliphatic alcohols (C5–C16) in organic solvents (hexane and diethyl ether). The catalysts operate in this reaction for several tens of reaction cycles (>40) without loss of activity. The recombinant rPichia/lip lipase immobilized on silica exhibits the most pronounced specificity for its first substrate, a fatty acid. For instance, the rate of synthesis for esters of low molecular weight acids (С4–С6) is three to four times slower than for the esters of acids with more than seven carbon atoms. The catalyst has a relatively broad specificity for the second substrate, an aliphatic alcohol. It is found that the ester of enanthic acid (C7:0) and butanol (C4) is synthesized at the maximum rate.

AB - Heterogeneous biocatalysts prepared by immobilizing a recombinant lipase from Thermomyces lanuginosus on mesoporous inorganic supports—silica (SiO2), alumina (Al2O3), and titania (TiO2)—are comparatively studied in the esterification of fatty acids with aliphatic alcohols. It is found that the T. lanuginosus lipase adsorbed on silica has the highest esterifying activity, while the lipase adsorbed on titania is completely inactivated. SiO2-based catalysts have high activity and stability in the esterification of saturated fatty acids containing 4–18 carbon atoms (C4–C18) with aliphatic alcohols (C5–C16) in organic solvents (hexane and diethyl ether). The catalysts operate in this reaction for several tens of reaction cycles (>40) without loss of activity. The recombinant rPichia/lip lipase immobilized on silica exhibits the most pronounced specificity for its first substrate, a fatty acid. For instance, the rate of synthesis for esters of low molecular weight acids (С4–С6) is three to four times slower than for the esters of acids with more than seven carbon atoms. The catalyst has a relatively broad specificity for the second substrate, an aliphatic alcohol. It is found that the ester of enanthic acid (C7:0) and butanol (C4) is synthesized at the maximum rate.

KW - aliphatic alcohols

KW - biocatalysts

KW - esterification

KW - fatty acids

KW - recombinant lipase

KW - ESTERS

KW - MEDIA

KW - LIPASE

KW - SILICA

KW - SELECTIVITY

UR - http://www.scopus.com/inward/record.url?scp=85045040104&partnerID=8YFLogxK

U2 - 10.1134/S2070050418010075

DO - 10.1134/S2070050418010075

M3 - Article

AN - SCOPUS:85045040104

VL - 10

SP - 68

EP - 74

JO - Catalysis in Industry

JF - Catalysis in Industry

SN - 2070-0504

IS - 1

ER -

ID: 12419420