Research output: Contribution to journal › Article › peer-review
Assessment of polygenic risk of hypertension. / Limonova, A. S.; Ershova, A. I.; Kiseleva, A. V. et al.
In: Cardiovascular Therapy and Prevention (Russian Federation), Vol. 21, No. 12, 3464, 2022.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Assessment of polygenic risk of hypertension
AU - Limonova, A. S.
AU - Ershova, A. I.
AU - Kiseleva, A. V.
AU - Ramensky, V. E.
AU - Vyatkin, Yu V.
AU - Kutsenko, V. A.
AU - Meshkov, A. N.
AU - Drapkina, O. M.
N1 - Публикация для корректировки.
PY - 2022
Y1 - 2022
N2 - Hypertension (HTN) is a leading risk factor for the development of cardiovascular diseases. In recent decades, the rapid development of genetic tests, in particular genome-wide association study (GWAS), has made it possible to identify hundreds of nucleotide sequence variants associated with the development of HTN. One approach to improve the predictive power of genetic testing is to combine information about many nucleotide sequence variants into a single risk assessment system, often referred to as a genetic risk score. Within the framework of this review, the most significant publications on the study of the genetic risk score for HTN will be considered, and the features of their development and application will be discussed.
AB - Hypertension (HTN) is a leading risk factor for the development of cardiovascular diseases. In recent decades, the rapid development of genetic tests, in particular genome-wide association study (GWAS), has made it possible to identify hundreds of nucleotide sequence variants associated with the development of HTN. One approach to improve the predictive power of genetic testing is to combine information about many nucleotide sequence variants into a single risk assessment system, often referred to as a genetic risk score. Within the framework of this review, the most significant publications on the study of the genetic risk score for HTN will be considered, and the features of their development and application will be discussed.
KW - genetic risk score
KW - hypertension
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85168156270&origin=inward&txGid=426b7a2fac220fc16b32f26f6e9d8f3d
UR - https://www.mendeley.com/catalogue/6f0e5a4c-68a0-3222-8ade-145147683b7b/
U2 - 10.15829/1728-8800-2022-3464
DO - 10.15829/1728-8800-2022-3464
M3 - Article
VL - 21
JO - Cardiovascular Therapy and Prevention (Russian Federation)
JF - Cardiovascular Therapy and Prevention (Russian Federation)
SN - 1728-8800
IS - 12
M1 - 3464
ER -
ID: 55721356