Standard

Amorphous drugs: Benefits and challenges. / Rams-Baron, Marzena; Jachowicz, Renata; Boldyreva, Elena et al.

Springer International Publishing AG, 2018. 230 p.

Research output: Book/Report › Book › Research › peer-review

Harvard

Rams-Baron, M, Jachowicz, R, Boldyreva, E, Zhou, D, Jamroz, W & Paluch, M 2018, Amorphous drugs: Benefits and challenges. Springer International Publishing AG. https://doi.org/10.1007/978-3-319-72002-9

APA

Rams-Baron, M., Jachowicz, R., Boldyreva, E., Zhou, D., Jamroz, W., & Paluch, M. (2018). Amorphous drugs: Benefits and challenges. Springer International Publishing AG. https://doi.org/10.1007/978-3-319-72002-9

Vancouver

Rams-Baron M, Jachowicz R, Boldyreva E, Zhou D, Jamroz W, Paluch M. Amorphous drugs: Benefits and challenges. Springer International Publishing AG, 2018. 230 p. doi: 10.1007/978-3-319-72002-9

Author

Rams-Baron, Marzena ; Jachowicz, Renata ; Boldyreva, Elena et al. / Amorphous drugs: Benefits and challenges. Springer International Publishing AG, 2018. 230 p.

BibTeX

@book{7b723083429e4fcc90e1ddb62a27ceec,
title = "Amorphous drugs: Benefits and challenges",
abstract = "This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.",
keywords = "Absorption enhancement, Amorphous drug formulations, Amorphous pharmaceuticals, Drug solubility, Glass transition, Increasing bioavailability of drug compounds, Order and disorder in the solid state, Pharmaceutical amorphous solid dispersions, Recrystallization, Solubility enhancement",
author = "Marzena Rams-Baron and Renata Jachowicz and Elena Boldyreva and Deliang Zhou and Witold Jamroz and Marian Paluch",
year = "2018",
month = jan,
day = "1",
doi = "10.1007/978-3-319-72002-9",
language = "English",
isbn = "9783319720012",
publisher = "Springer International Publishing AG",
address = "Switzerland",

}

RIS

TY - BOOK

T1 - Amorphous drugs: Benefits and challenges

AU - Rams-Baron, Marzena

AU - Jachowicz, Renata

AU - Boldyreva, Elena

AU - Zhou, Deliang

AU - Jamroz, Witold

AU - Paluch, Marian

PY - 2018/1/1

Y1 - 2018/1/1

N2 - This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

AB - This book explains theoretical and technological aspects of amorphous drug formulations. It is intended for all those wishing to increase their knowledge in the field of amorphous pharmaceuticals. Conversion of crystalline material into the amorphous state, as described in this book, is a way to overcome limited water solubility of drug formulations, in this way enhancing the chemical activity and bioavailability inside the body. Written by experts from various fields and backgrounds, the book introduces to fundamental physical aspects (explaining differences between the ordered and the disordered solid states, the enhancement of solubility resulting from drugs amorphization, physical instability and how it can be overcome) as well as preparation and formulation procedures to produce and stabilize amorphous pharmaceuticals. Readers will thus gain a well-funded understanding and find a multi-faceted discussion of the properties and advantages of amorphous drugs and of the challenges in producing and stabilizing them. The book is an ideal source of information for researchers and students as well as professionals engaged in research and development of amorphous pharmaceutical products.

KW - Absorption enhancement

KW - Amorphous drug formulations

KW - Amorphous pharmaceuticals

KW - Drug solubility

KW - Glass transition

KW - Increasing bioavailability of drug compounds

KW - Order and disorder in the solid state

KW - Pharmaceutical amorphous solid dispersions

KW - Recrystallization

KW - Solubility enhancement

UR - http://www.scopus.com/inward/record.url?scp=85045983030&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-72002-9

DO - 10.1007/978-3-319-72002-9

M3 - Book

AN - SCOPUS:85045983030

SN - 9783319720012

BT - Amorphous drugs: Benefits and challenges

PB - Springer International Publishing AG

ER -

ID: 25438463