Research output: Contribution to journal › Article › peer-review
A study of plant coumarins 16*. Synthesis and transformations of 7-alkynylcoumarins. / Lipeeva, Alla V.; Shults, Elvira E.
In: Chemistry of Heterocyclic Compounds, Vol. 53, No. 12, 01.12.2017, p. 1302-1309.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A study of plant coumarins 16*. Synthesis and transformations of 7-alkynylcoumarins
AU - Lipeeva, Alla V.
AU - Shults, Elvira E.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - 7-Alkynyl-substituted coumarins were synthesized by a Sonogashira reaction of 6-substituted 7-(trifluoromethylsulfonyloxy)coumarins with terminal acetylenes. The reaction of 7-ethynyl-substituted coumarins with azidobenzoic acids in the presence of copper(II) sulfate and sodium ascorbate was used to synthesize the respective 7-[(1-carboxyphenyl)-1H-1,2,3-triazol-4-yl]coumarins.
AB - 7-Alkynyl-substituted coumarins were synthesized by a Sonogashira reaction of 6-substituted 7-(trifluoromethylsulfonyloxy)coumarins with terminal acetylenes. The reaction of 7-ethynyl-substituted coumarins with azidobenzoic acids in the presence of copper(II) sulfate and sodium ascorbate was used to synthesize the respective 7-[(1-carboxyphenyl)-1H-1,2,3-triazol-4-yl]coumarins.
KW - 1,2,3-triazoles
KW - arylalkynes
KW - coumarins
KW - CuААС reaction
KW - Sonogashira reaction
KW - Cu reaction
KW - METABOLITES
KW - HECK
KW - MEDICINAL CHEMISTRY
KW - CROSS-COUPLING REACTIONS
KW - CuAAC reaction
KW - ANTICANCER
KW - AGENTS
KW - HYBRIDS
UR - http://www.scopus.com/inward/record.url?scp=85040926210&partnerID=8YFLogxK
U2 - 10.1007/s10593-018-2210-5
DO - 10.1007/s10593-018-2210-5
M3 - Article
AN - SCOPUS:85040926210
VL - 53
SP - 1302
EP - 1309
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 12
ER -
ID: 9265482