A New Look at Structural Changes in the Aortic Root in Aortic Valve Stenosis. / Kobelev, E.; Bergen, T. A.; Tarkova, A. R. et al.
In: Sovremennye Tehnologii v Medicine, Vol. 14, No. 2, 5, 2022, p. 51-56.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - A New Look at Structural Changes in the Aortic Root in Aortic Valve Stenosis
AU - Kobelev, E.
AU - Bergen, T. A.
AU - Tarkova, A. R.
AU - Krestyaninov, O. V.
AU - Bobrikova, E. E.
AU - Safro, I. K.
AU - Chernyavsky, A. M.
AU - Zhuravleva, I. Yu
N1 - Kobelev E., Bergen T.A., Tarkova A.R., Krestyaninov O.V., Bobrikova E.E., Safro I.K., Chernyavsky A.M., Zhuravleva I.Yu. A new look at structural changes in the aortic root in aortic valve stenosis. Sovremennye tehnologii v medicine 2022; 14(2):51. Publisher Copyright: © 2022, Privolzhsky Research Medical University. All rights reserved.
PY - 2022
Y1 - 2022
N2 - The aim of the study was to identify new anatomical landmarks of the aortic root and the relationship between the sizes of anatomical structures using the method of computed tomography angiography to improve models of heart valves and the methods for their selection in clinical practice. Materials and Methods. The dataset of computed tomography angiography prior to aortic valve replacement in 262 patients was analyzed. The mean age was 75.0±5.9 years. 99 (37.8±3.0%) men and 163 (62.2±3.0%) women took part in the study. The annulus fibrosus, sinotubular junction, and height of the sinuses of Valsalva were measured. Results. In the tricuspid aortic valve group (n=251), in more than 50% of the cases, the diameter of the annulus fibrosus ranged from 23 to 26 mm. No significant association between the diameter of the annulus fibrosus and patient height (r=0.35; p=0.01) or body surface area (r=0.25; p=0.01) and the height of the sinuses of Valsalva (r=0.34; p=0.01) were revealed. Based on the ratio of the height of the sinuses of Valsalva and the diameter of the annulus fibrosus, three variants of the structure of the aortic root were identified: Type A — K>1.05; type B — 0.95≤K≤1.05; type C — K<0.95Type C of the aortic root was found to predominate in most cases, namely, in 98.0±0.9% (n=246). In the bicuspid aortic valve group (n=11), 2 patients had a type A valve, 1 patient had a type B valve, and 8 patients had a type C valve. Conclusion. A classification of variants of the aortic root structure has been proposed, which will be useful not only for practitioners when choosing a treatment method, but also for researchers to understand the structural characteristics of the aortic root in patients with its pathology.
AB - The aim of the study was to identify new anatomical landmarks of the aortic root and the relationship between the sizes of anatomical structures using the method of computed tomography angiography to improve models of heart valves and the methods for their selection in clinical practice. Materials and Methods. The dataset of computed tomography angiography prior to aortic valve replacement in 262 patients was analyzed. The mean age was 75.0±5.9 years. 99 (37.8±3.0%) men and 163 (62.2±3.0%) women took part in the study. The annulus fibrosus, sinotubular junction, and height of the sinuses of Valsalva were measured. Results. In the tricuspid aortic valve group (n=251), in more than 50% of the cases, the diameter of the annulus fibrosus ranged from 23 to 26 mm. No significant association between the diameter of the annulus fibrosus and patient height (r=0.35; p=0.01) or body surface area (r=0.25; p=0.01) and the height of the sinuses of Valsalva (r=0.34; p=0.01) were revealed. Based on the ratio of the height of the sinuses of Valsalva and the diameter of the annulus fibrosus, three variants of the structure of the aortic root were identified: Type A — K>1.05; type B — 0.95≤K≤1.05; type C — K<0.95Type C of the aortic root was found to predominate in most cases, namely, in 98.0±0.9% (n=246). In the bicuspid aortic valve group (n=11), 2 patients had a type A valve, 1 patient had a type B valve, and 8 patients had a type C valve. Conclusion. A classification of variants of the aortic root structure has been proposed, which will be useful not only for practitioners when choosing a treatment method, but also for researchers to understand the structural characteristics of the aortic root in patients with its pathology.
KW - 3D modeling of the aortic root
KW - Aortic stenosis
KW - Aortic valve
KW - Computed tomography
KW - Transcatheter aortic valve implantation
KW - Tomography, X-Ray Computed/methods
KW - Humans
KW - Male
KW - Aorta, Thoracic/pathology
KW - Aortic Valve Stenosis/diagnostic imaging
KW - Aorta/diagnostic imaging
KW - Aged, 80 and over
KW - Female
KW - Aged
KW - Aortic Valve/diagnostic imaging
UR - http://www.scopus.com/inward/record.url?scp=85133183189&partnerID=8YFLogxK
UR - https://www.elibrary.ru/item.asp?id=48504442
UR - https://www.mendeley.com/catalogue/759aa69e-ca19-353d-900e-797d6fb169c5/
U2 - 10.17691/stm2022.14.2.05
DO - 10.17691/stm2022.14.2.05
M3 - Article
C2 - 37065425
AN - SCOPUS:85133183189
VL - 14
SP - 51
EP - 56
JO - Современные технологии в медицине
JF - Современные технологии в медицине
SN - 2076-4243
IS - 2
M1 - 5
ER -
ID: 36541153